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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL504349
Molecular formula	C34H42FN5O4
IUPAC name	(2S)-2-[(3S)-4-[(2R)-3-(4-fluorophenyl)-2-[[(2S)-2-(methylamino)propanoyl]amino]propanoyl]-2-oxo-3-propylpiperazin-1-yl]-N-methyl-3-naphthalen-2-ylpropanamide
Molecular weight	603.739
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	4.3
Synonyms	(2S)-N-Methyl-2-[(3S)-4-(N-methyl-L-alanyl-4-fluoro-D-phenylalanyl)-2-oxo-3-propyl-1-piperazinyl]-3-(2-naphthalenyl)propanamide BDBM50253746
Inchi Key	AHYGIWNTGDKMRR-SUAIOLNFSA-N
Inchi ID	InChI=1S/C34H42FN5O4/c1-5-8-29-34(44)40(30(32(42)37-4)21-24-11-14-25-9-6-7-10-26(25)19-24)18-17-39(29)33(43)28(38-31(41)22(2)36-3)20-23-12-15-27(35)16-13-23/h6-7,9-16,19,22,28-30,36H,5,8,17-18,20-21H2,1-4H3,(H,37,42)(H,38,41)/t22-,28+,29-,30-/m0/s1
PubChem CID	25129109
ChEMBL	CHEMBL504349
IUPHAR	N/A
BindingDB	50253746
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5982	Melanocortin receptor 3	P41968	MC3R	Homo sapiens (Human)	323
5980	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332
5981	Melanocyte-stimulating hormone receptor	Q01726	MC1R	Homo sapiens (Human)	317

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