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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Lesopitron
Molecular formula	C15H21ClN6
IUPAC name	2-[4-[4-(4-chloropyrazol-1-yl)butyl]piperazin-1-yl]pyrimidine
Molecular weight	320.825
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	1.8
Synonyms	PDSP2_000055 2-[4-[4-(4-chloropyrazol-1-yl)butyl]piperazin-1-yl]pyrimidine CAS_132449-46-8 Lesopitran Lesopitron dihydrochloride < Rec INNM > ZINC1547604 NSC_60813 132449-46-8 AHCPKWJUALHOPH-UHFFFAOYSA-N H1CGM4755H SCHEMBL246589 2-[4-[4-(4-chloropyrazol-1-yl)butyl]piperazin-1-yl]pyrimidine dihydrochloride CHEMBL2105051 Lesopitran) Lesopitron [INN] AC1L1TZ2 DB04970 PDSP1_000055 2-(4-(4-(4-Chloropyrazol-1-yl)butyl)-1-piperazinyl)pyrimidine BDBM82365 L001393 UNII-H1CGM4755H 2-{4- [4- (4-chloro-1-pyrazolyl)-butyl]-1-piperazinyl}pyrimidine D0G5TU lesopitron[inn] AC1Q3PNJ DTXSID40157587 [ Show all ]
Inchi Key	AHCPKWJUALHOPH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H21ClN6/c16-14-12-19-22(13-14)7-2-1-6-20-8-10-21(11-9-20)15-17-4-3-5-18-15/h3-5,12-13H,1-2,6-11H2
PubChem CID	60813
ChEMBL	N/A
IUPHAR	N/A
BindingDB	82365
DrugBank	DB04970
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5439	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422

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