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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL279729
Molecular formula	C19H28ClN3O2
IUPAC name	N-[[(2R)-1-butylpyrrolidin-2-yl]methyl]-6-chloro-4-methyl-2,3-dihydro-1,4-benzoxazine-8-carboxamide
Molecular weight	365.902
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.5
Synonyms	6-Chloro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((R)-1-butyl-pyrrolidin-2-ylmethyl)-amide BDBM50086863 N-[[(2R)-1-Butyl-2-pyrrolidinyl]methyl]-4-methyl-6-chloro-3,4-dihydro-2H-1,4-benzoxazine-8-carboxamide SCHEMBL7269304
Inchi Key	AHCLBNDBOQTPGQ-OAHLLOKOSA-N
Inchi ID	InChI=1S/C19H28ClN3O2/c1-3-4-7-23-8-5-6-15(23)13-21-19(24)16-11-14(20)12-17-18(16)25-10-9-22(17)2/h11-12,15H,3-10,13H2,1-2H3,(H,21,24)/t15-/m1/s1
PubChem CID	44457584
ChEMBL	CHEMBL279729
IUPHAR	N/A
BindingDB	50086863
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5436	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
5437	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
5438	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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