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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3927136
Molecular formula	C30H42N2O5
IUPAC name	[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11-hydroxy-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]methyl (2S,3S)-2-amino-3-methylpentanoate
Molecular weight	510.675
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	4.4
Synonyms	BDBM199419 SCHEMBL15485950 US9221831, 85
Inchi Key	AGUKEFSLHJXTQC-WLQXWTRFSA-N
Inchi ID	InChI=1S/C30H42N2O5/c1-4-17(2)24(31)26(34)36-16-20-14-28-9-10-30(20,35-3)27-29(28)11-12-32(15-18-5-6-18)22(28)13-19-7-8-21(33)25(37-27)23(19)29/h7-8,17-18,20,22,24,27,33H,4-6,9-16,31H2,1-3H3/t17-,20+,22+,24-,27+,28+,29-,30+/m0/s1
PubChem CID	89978732
ChEMBL	CHEMBL3927136
IUPHAR	N/A
BindingDB	199419
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
536068	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
536067	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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