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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1783868
Molecular formula	C20H18N4OS
IUPAC name	5-(4-methylphenyl)-13-(2-methylprop-2-enylamino)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,9,11-pentaen-6-one
Molecular weight	362.451
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.7
Synonyms	SCHEMBL8244563 9-(2-Methyl-allylamino)-3-p-tolyl-3H-pyrido[3'',2'':4,5]thieno[3,2-d]pyrimidin-4-one BDBM50345941
Inchi Key	AFKSTFXIAKZKBK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H18N4OS/c1-12(2)10-22-15-8-9-21-19-16(15)17-18(26-19)20(25)24(11-23-17)14-6-4-13(3)5-7-14/h4-9,11H,1,10H2,2-3H3,(H,21,22)
PubChem CID	54585405
ChEMBL	CHEMBL1783868
IUPHAR	N/A
BindingDB	50345941
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4246	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
4247	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
4245	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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