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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000557830
Molecular formula	C24H23N3O
IUPAC name	2-(3,4-dihydro-1H-isoquinolin-2-yl)-7-(4-methylphenyl)-7,8-dihydro-6H-quinazolin-5-one
Molecular weight	369.468
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.1
Synonyms	CHEMBL1400890 STK211304 7-(4-methylphenyl)-2-(2-1,2,3,4-tetrahydroisoquinolyl)-6,7,8-trihydroquinazoli n-5-one AKOS000613900 MCULE-9014633166 2-(3,4-dihydro-1H-isoquinolin-2-yl)-7-(4-methylphenyl)-7,8-dihydro-6H-quinazolin-5-one CCG-123939 SMR000148546 2-(3,4-dihydroisoquinolin-2(1H)-yl)-7-(4-methylphenyl)-7,8-dihydroquinazolin-5(6H)-one 842957-38-4 cid_4563710 AKOS016163892 2-(3,4-dihydro-1H-isoquinolin-2-yl)-7-(p-tolyl)-7,8-dihydro-6H-quinazolin-5-one ST50162082 AC1NCRV7 HMS2416G23 BDBM41674 MolPort-000-413-795 2-(3,4-Dihydro-1H-isoquinolin-2-yl)-7-p-tolyl-7,8-dihydro-6H-quinazolin-5-one [ Show all ]
Inchi Key	AEKWYFFLXFCONP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H23N3O/c1-16-6-8-18(9-7-16)20-12-22-21(23(28)13-20)14-25-24(26-22)27-11-10-17-4-2-3-5-19(17)15-27/h2-9,14,20H,10-13,15H2,1H3
PubChem CID	4563710
ChEMBL	CHEMBL1400890
IUPHAR	N/A
BindingDB	41674
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3583	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
3582	Sphingosine 1-phosphate receptor 2	O95136	S1PR2	Homo sapiens (Human)	353

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