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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL26790
Molecular formula	C33H36Cl2N4O2
IUPAC name	3-[1-[3-[1-benzyl-3-(3,4-dichlorophenyl)-6-oxopiperidin-3-yl]propyl]piperidin-4-yl]-1H-benzimidazol-2-one
Molecular weight	591.577
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	6.1
Synonyms	BDBM50070353 SCHEMBL7842031 1-(1-{3-[1-Benzyl-3-(3,4-dichloro-phenyl)-6-oxo-piperidin-3-yl]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one
Inchi Key	ADXFJIYJEFFOSY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C33H36Cl2N4O2/c34-27-12-11-25(21-28(27)35)33(17-13-31(40)38(23-33)22-24-7-2-1-3-8-24)16-6-18-37-19-14-26(15-20-37)39-30-10-5-4-9-29(30)36-32(39)41/h1-5,7-12,21,26H,6,13-20,22-23H2,(H,36,41)
PubChem CID	23294208
ChEMBL	CHEMBL26790
IUPHAR	N/A
BindingDB	50070353
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3202	C-C chemokine receptor type 5	P51681	CCR5	Homo sapiens (Human)	352
3201	Neuromedin-K receptor	P29371	TACR3	Homo sapiens (Human)	465
3199	Substance-K receptor	P21452	TACR2	Homo sapiens (Human)	398
3200	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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