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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL376920
Molecular formula	C19H15N3
IUPAC name	2-amino-4-(4-methylphenyl)-6-phenylpyridine-3-carbonitrile
Molecular weight	285.35
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.4
Synonyms	2-amino-4-(4-methylphenyl)-6-phenyl-3-pyridyl cyanide BAS 00789881 SR-01000520248-1 2-amino-6-phenyl-4-p-tolylnicotinonitrile ZINC19818501 2-amino-3-cyano-4-(4-methylphenyl)-6-phenylpyridine AC1LEZMJ MolPort-000-994-656 2-amino-4-(4-methylphenyl)-6-phenylpyridine-3-carbonitrile BDBM50194811 ST4039142 D06NQD 2-Amino-4-(4-methylphenyl)-6-phenyl-3-pyridinecarbonitrile AKOS000286711 SR-01000520248 2-Amino-6-phenyl-4-p-tolyl-nicotinonitrile STK696423 A1811/0076551 MCULE-7406561707 [ Show all ]
Inchi Key	ADSZRHDJWBZORK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H15N3/c1-13-7-9-14(10-8-13)16-11-18(15-5-3-2-4-6-15)22-19(21)17(16)12-20/h2-11H,1H3,(H2,21,22)
PubChem CID	695136
ChEMBL	CHEMBL376920
IUPHAR	N/A
BindingDB	50194811
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3060	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
3059	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412

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