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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL317532
Molecular formula	C26H28FNO4
IUPAC name	6-fluoro-8-[2-[4-(4-methoxynaphthalen-1-yl)butylamino]ethoxy]-2,3-dihydrochromen-4-one
Molecular weight	437.511
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.9
Synonyms	8-[2-[[4-(4-Methoxy-1-naphthyl)butyl]amino]ethoxy]-6-fluoro-2,3-dihydro-4H-1-benzopyran-4-one BDBM50065574 6-Fluoro-8-{2-[4-(4-methoxy-naphthalen-1-yl)-butylamino]-ethoxy}-chroman-4-one
Inchi Key	ADQOQGKIFXKTKW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H28FNO4/c1-30-24-10-9-18(20-7-2-3-8-21(20)24)6-4-5-12-28-13-15-31-25-17-19(27)16-22-23(29)11-14-32-26(22)25/h2-3,7-10,16-17,28H,4-6,11-15H2,1H3
PubChem CID	10670618
ChEMBL	CHEMBL317532
IUPHAR	N/A
BindingDB	50065574
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2977	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
2979	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
2978	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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