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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL224615
Molecular formula	C17H14N4OS
IUPAC name	13-(dimethylamino)-5-phenyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,9,11-pentaen-6-one
Molecular weight	322.386
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.2
Synonyms	AC1LF8AZ HMS1380N11 SMR000069218 Cambridge id 5240467 MCULE-4877268593 9-dimethylamino-3-phenyl-3H-pyrido[3'',2'':4,5]thieno[3,2-d]pyrimidin-4-one Oprea1_187971 AH-262/36083015 HMS2401K09 ZINC77553 CCG-20549 MLS000061150 AB00076338-01 ChemDiv2_004169 SCHEMBL8238029 BDBM50177079 IDI1_002884 9-(dimethylamino)-3-phenylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one MolPort-002-112-056 [ Show all ]
Inchi Key	ADOZDJQXPOGXEV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H14N4OS/c1-20(2)12-8-9-18-16-13(12)14-15(23-16)17(22)21(10-19-14)11-6-4-3-5-7-11/h3-10H,1-2H3
PubChem CID	699222
ChEMBL	CHEMBL224615
IUPHAR	N/A
BindingDB	50177079
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2929	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
2930	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
2931	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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