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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1MHBGG
Molecular formula	C20H14F3N5
IUPAC name	3-[3-phenyl-5-[2-(trifluoromethyl)benzimidazol-1-yl]pyrazol-1-yl]propanenitrile
Molecular weight	381.362
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.9
Synonyms	STL271435 CHEMBL1458525 3-[3-phenyl-5-[2-(trifluoromethyl)benzimidazol-1-yl]pyrazol-1-yl]propanenitrile MLS000058111 AKOS016368205 HMS2319F07 3-{3-phenyl-5-[2-(trifluoromethyl)-1H-benzimidazol-1-yl]-1H-pyrazol-1-yl}propanenitrile SMR000067455 MCULE-3354090889 [ Show all ]
Inchi Key	ADKQOIQFGWKBOU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H14F3N5/c21-20(22,23)19-25-15-9-4-5-10-17(15)28(19)18-13-16(14-7-2-1-3-8-14)26-27(18)12-6-11-24/h1-5,7-10,13H,6,12H2
PubChem CID	2999296
ChEMBL	CHEMBL1458525
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2386	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
2385	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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