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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000556811
Molecular formula	C25H34N2O3
IUPAC name	5-tert-butyl-N-[2-(cyclopentylamino)-2-oxoethyl]-N-(2,6-dimethylphenyl)-3-methylfuran-2-carboxamide
Molecular weight	410.558
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.8
Synonyms	5-tert-butyl-N-[2-(cyclopentylamino)-2-keto-ethyl]-N-(2,6-dimethylphenyl)-3-methyl-2-furamide CHEMBL1458360 5-tert-butyl-N-[2-(cyclopentylamino)-2-oxoethyl]-N-(2,6-dimethylphenyl)-3-methylfuran-2-carboxamide BDBM46897 5-tert-butyl-N-[2-(cyclopentylamino)-2-oxidanylidene-ethyl]-N-(2,6-dimethylphenyl)-3-methyl-furan-2-carboxamide cid_1454983 AC1LRXHG SMR000173544 5-tert-Butyl-3-methyl-furan-2-carboxylic acid cyclopentylcarbamoylmethyl-(2,6-dimethyl-phenyl)-amide 5-tert-butyl-N-[2-(cyclopentylamino)-2-oxoethyl]-N-(2,6-dimethylphenyl)-3-methyl-2-furancarboxamide HMS2471H16 ASN 06744255 [ Show all ]
Inchi Key	ADFOFBMTHOLHHF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H34N2O3/c1-16-10-9-11-17(2)22(16)27(15-21(28)26-19-12-7-8-13-19)24(29)23-18(3)14-20(30-23)25(4,5)6/h9-11,14,19H,7-8,12-13,15H2,1-6H3,(H,26,28)
PubChem CID	1454983
ChEMBL	CHEMBL1458360
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2227	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
2226	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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