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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3913414
Molecular formula	C17H18Cl2N2O6
IUPAC name	(1S,2R,3R,4S,5R,6S)-4-acetamido-2-amino-3-[(3,4-dichlorophenyl)methoxy]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Molecular weight	417.239
Hydrogen bond acceptor	7
Hydrogen bond donor	4
XlogP	-1.9
Synonyms	(1S,2R,3R,4S,5R,6S)-4-(Acetylamino)-2-amino-3-[(3,4-dichlorobenzyl)oxy]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid BDBM50204259 SCHEMBL8832063 ACVCREFNDLDKHC-SGPHYXEKSA-N
Inchi Key	ACVCREFNDLDKHC-SGPHYXEKSA-N
Inchi ID	InChI=1S/C17H18Cl2N2O6/c1-6(22)21-13-10-11(15(23)24)12(10)17(20,16(25)26)14(13)27-5-7-2-3-8(18)9(19)4-7/h2-4,10-14H,5,20H2,1H3,(H,21,22)(H,23,24)(H,25,26)/t10-,11-,12-,13-,14+,17+/m0/s1
PubChem CID	67705376
ChEMBL	CHEMBL3913414
IUPHAR	N/A
BindingDB	50204259
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
535965	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
535966	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879

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