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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000082992
Molecular formula	C16H13FN6S
IUPAC name	6-(4-fluorophenyl)-3-(1,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
Molecular weight	340.38
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.7
Synonyms	850764-14-6 AKOS032393163 SMR000046733 6-(4-fluorophenyl)-3-(1,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine HMS2276J06 AC1LDE28 MolPort-000-773-621 STK567660 6-(4-fluorophenyl)-3-(2,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine MCULE-6619686921 AKOS005493002 MolPort-002-632-238 CHEMBL1382951 ZINC4038504 [ Show all ]
Inchi Key	ACVBVAZZTCFOQR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H13FN6S/c17-10-6-4-9(5-7-10)13-8-24-16-21-20-15(23(16)22-13)14-11-2-1-3-12(11)18-19-14/h4-7H,1-3,8H2,(H,18,19)
PubChem CID	665554
ChEMBL	CHEMBL1382951
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1960	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
1961	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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