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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000333603
Molecular formula	C18H15N3O2S
IUPAC name	(5Z)-5-[(4-prop-2-enoxyphenyl)methylidene]-2-pyridin-3-ylimino-1,3-thiazolidin-4-one
Molecular weight	337.397
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.6
Synonyms	(5Z)-5-[(4-prop-2-enoxyphenyl)methylidene]-2-(pyridin-3-ylamino)-1,3-thiazol-4-one CHEMBL1406249 ZINC13121985 5-[1-(4-Allyloxy-phenyl)-meth-(Z)-ylidene]-2-(pyridin-3-ylamino)-thiazol-4-one MolPort-002-628-951 AKOS022096442 STL307724 (5Z)-5-[4-(prop-2-en-1-yloxy)benzylidene]-2-(pyridin-3-ylamino)-1,3-thiazol-4(5H)-one HMS2805J08 862105-56-4 MolPort-042-646-585 (2E,5Z)-5-[4-(prop-2-en-1-yloxy)benzylidene]-2-(pyridin-3-ylimino)-1,3-thiazolidin-4-one STL491653 (Z)-5-(4-(allyloxy)benzylidene)-2-(pyridin-3-ylamino)thiazol-4(5H)-one AC1O10A6 SMR000437718 [ Show all ]
Inchi Key	ACUYNBKYLPUVPS-WJDWOHSUSA-N
Inchi ID	InChI=1S/C18H15N3O2S/c1-2-10-23-15-7-5-13(6-8-15)11-16-17(22)21-18(24-16)20-14-4-3-9-19-12-14/h2-9,11-12H,1,10H2,(H,20,21,22)/b16-11-
PubChem CID	135538580
ChEMBL	CHEMBL1406249
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1956	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
1957	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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