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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	N-[1-(4-chlorophenyl)-2,5-dioxo-3-pyrrolidinyl]-N-(4-methoxybenzyl)-N'-methylthiourea
Molecular formula	C20H20ClN3O3S
IUPAC name	1-[1-(4-chlorophenyl)-2,5-dioxopyrrolidin-3-yl]-1-[(4-methoxyphenyl)methyl]-3-methylthiourea
Molecular weight	417.908
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.9
Synonyms	1-[1-(4-chlorophenyl)-2,5-dioxopyrrolidin-3-yl]-1-[(4-methoxyphenyl)methyl]-3-methylthiourea MLS000544283 AKOS003793104 SMR000159614 HMS2348P21 AC1NPNAW MolPort-002-794-117 STK958135 1-[1-(4-chlorophenyl)-2,5-dioxopyrrolidin-3-yl]-1-(4-methoxybenzyl)-3-methylthiourea MCULE-2826826728 AK-968/40344553 CHEMBL1379059 [ Show all ]
Inchi Key	ACBIVSGMHXXZHJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H20ClN3O3S/c1-22-20(28)23(12-13-3-9-16(27-2)10-4-13)17-11-18(25)24(19(17)26)15-7-5-14(21)6-8-15/h3-10,17H,11-12H2,1-2H3,(H,22,28)
PubChem CID	5206893
ChEMBL	CHEMBL1379059
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1401	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
1402	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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