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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	BAS 09530603
Molecular formula	C21H23F2N5O
IUPAC name	[7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(4-ethylpiperazin-1-yl)methanone
Molecular weight	399.446
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	2.6
Synonyms	7-(difluoromethyl)-3-[(4-ethylpiperazin-1-yl)carbonyl]-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine MLS000070985 [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(4-ethylpiperazin-1-yl)methanone SCHEMBL4205363 HMS2421J16 ZINC55260881 AC1LD9J4 MLS002537825 SMR000015081 (7-Difluoromethyl-5-p-tolyl-pyrazolo[1,5-a]pyrimidin-3-yl)-(4-ethyl-piperazin-1-yl)-methanone MCULE-1259795032 [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl](4-ethylpiperazin-1-yl)methanone AKOS000600094 MolPort-001-569-118 CHEMBL1490963 STK961097 [ Show all ]
Inchi Key	ABRBJPZAPLWUTA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H23F2N5O/c1-3-26-8-10-27(11-9-26)21(29)16-13-24-28-18(19(22)23)12-17(25-20(16)28)15-6-4-14(2)5-7-15/h4-7,12-13,19H,3,8-11H2,1-2H3
PubChem CID	644567
ChEMBL	CHEMBL1490963
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1090	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
1089	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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