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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL180742
Molecular formula	C26H22Cl2O4
IUPAC name	(E)-3-[2-[(E)-3-[2-[(2,6-dichlorophenyl)methoxy]-3-methylphenyl]-1-hydroxyprop-2-enyl]phenyl]prop-2-enoic acid
Molecular weight	469.358
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	6.4
Synonyms	BDBM50159773 SCHEMBL7807282 3-(2-{(E)-3-[2-(2,6-Dichloro-benzyloxy)-3-methyl-phenyl]-1-hydroxy-allyl}-phenyl)-acrylic acid SCHEMBL7807283
Inchi Key	ABHDIPZJDPNXNR-QUMQEAAQSA-N
Inchi ID	InChI=1S/C26H22Cl2O4/c1-17-6-4-8-19(26(17)32-16-21-22(27)10-5-11-23(21)28)12-14-24(29)20-9-3-2-7-18(20)13-15-25(30)31/h2-15,24,29H,16H2,1H3,(H,30,31)/b14-12+,15-13+
PubChem CID	22009011
ChEMBL	CHEMBL180742
IUPHAR	N/A
BindingDB	50159773
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
855	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
852	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
853	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
854	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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