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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1090526
Molecular formula	C20H24FN3O
IUPAC name	2-[6-fluoro-3-[(1R)-1-(3-methoxypyrazin-2-yl)ethyl]-1H-inden-2-yl]-N,N-dimethylethanamine
Molecular weight	341.43
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	2.7
Synonyms	BDBM50315205 (R)-2-(6-fluoro-3-(1-(3-methoxypyrazin-2-yl)ethyl)-1H-inden-2-yl)-N,N-dimethylethanamine
Inchi Key	ABDWUBPDHWDFCV-CYBMUJFWSA-N
Inchi ID	InChI=1S/C20H24FN3O/c1-13(19-20(25-4)23-9-8-22-19)18-14(7-10-24(2)3)11-15-12-16(21)5-6-17(15)18/h5-6,8-9,12-13H,7,10-11H2,1-4H3/t13-/m1/s1
PubChem CID	46884734
ChEMBL	CHEMBL1090526
IUPHAR	N/A
BindingDB	50315205
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
765	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
764	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
763	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460

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