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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1085560
Molecular formula	C24H26N4
IUPAC name	2,6-dimethyl-5-[6-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]quinolin-2-yl]pyridine-3-carbonitrile
Molecular weight	370.5
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.5
Synonyms	BDBM50319514 SCHEMBL1641115 (R)-2,6-dimethyl-5-(6-(2-(2-methylpyrrolidin-1-yl)ethyl)quinolin-2-yl)nicotinonitrile ABCLYDOXFRWKNB-MRXNPFEDSA-N 2,6-dimethyl-5-(6-{2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl}-2-quinolinyl)nicotinonitrile
Inchi Key	ABCLYDOXFRWKNB-MRXNPFEDSA-N
Inchi ID	InChI=1S/C24H26N4/c1-16-5-4-11-28(16)12-10-19-6-8-23-20(13-19)7-9-24(27-23)22-14-21(15-25)17(2)26-18(22)3/h6-9,13-14,16H,4-5,10-12H2,1-3H3/t16-/m1/s1
PubChem CID	46890475
ChEMBL	CHEMBL1085560
IUPHAR	N/A
BindingDB	50319514
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
737	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
738	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445

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