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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001110184
Molecular formula	C26H31N5O5S
IUPAC name	N-[(Z)-1-[1-(dimethylsulfamoyl)indol-3-yl]-3-(2-morpholin-4-ylethylamino)-3-oxoprop-1-en-2-yl]benzamide
Molecular weight	525.624
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	2.0
Synonyms	N-[(1Z)-1-[1-(dimethylsulfamoyl)-1H-indol-3-yl]-3-{[2-(morpholin-4-yl)ethyl]amino}-3-oxoprop-1-en-2-yl]benzamide CHEMBL1726252 ZINC25180710 MolPort-001-736-138 AKOS001509311 SMR000625406 HMS2933A21 N-((Z)-2-{1-[(dimethylamino)sulfonyl]-1H-indol-3-yl}-1-{[(2-morpholin-4-ylethyl)amino]carbonyl}vinyl)benzamide STL445176 [ Show all ]
Inchi Key	AAFGQGUAUKKREU-NKFKGCMQSA-N
Inchi ID	InChI=1S/C26H31N5O5S/c1-29(2)37(34,35)31-19-21(22-10-6-7-11-24(22)31)18-23(28-25(32)20-8-4-3-5-9-20)26(33)27-12-13-30-14-16-36-17-15-30/h3-11,18-19H,12-17H2,1-2H3,(H,27,33)(H,28,32)/b23-18-
PubChem CID	17038160
ChEMBL	CHEMBL1726252
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
462986	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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