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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Pyrimidin-4-ylacetamide, 26
Molecular formula	C19H24N6O2
IUPAC name	3-(dimethylamino)-N-[6-(3,5-dimethylpyrazol-1-yl)-2-(5-methylfuran-2-yl)pyrimidin-4-yl]propanamide
Molecular weight	368.441
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.0
Synonyms	CHEMBL410234 BDBM21211 N-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfuran-2-yl)pyrimidin-4-yl]-3-(dimethylamino)propanamide
Inchi Key	AACWUFIIMOHGSO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H24N6O2/c1-12-10-13(2)25(23-12)17-11-16(20-18(26)8-9-24(4)5)21-19(22-17)15-7-6-14(3)27-15/h6-7,10-11H,8-9H2,1-5H3,(H,20,21,22,26)
PubChem CID	24768433
ChEMBL	CHEMBL410234
IUPHAR	N/A
BindingDB	21211
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
69	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
70	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
71	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410

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