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GPCR

NameKappa-type opioid receptor
SpeciesBos taurus (Bovine)
GeneOPRK1
SynonymK-OR-1
KOR-1
DiseaseN/A for non-human GPCRs
Length380
Amino acid sequenceMEPPVQIFRGEPGPTCSPSTCLPPNGSGWFPGWAEPDGNGSAGSEDVLLEPAHISPVILVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKVVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWILSSSVGISAIVLGGTKVREDMEVIECSLQFPDDDYSWWDLFMKVCVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTAHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYVREVDGVNKPV
UniProtQ2KIP6
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLN/A
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 11
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
303702D structureMorphinan-3,6.alpha.-diol, 7,8-didehydro-4,5.alpha.-epoxy-17-methyl-C17H19NO3285.3434 / 20.8Yes
1160762D structureN-CPM-CACOC30H31N3O6529.5937 / 14.2No
1349952D structureHydromorphineC17H21NO3287.3594 / 21.8Yes
1842052D structureBDBM85393C27H27ClN2O4478.9735 / 13.9Yes
2003162D structureBDBM85395C30H31ClN2O4519.0385 / 15.0No
2035072D structureCUMI-101C19H27N5O3373.4576 / 01.8Yes
2203092D structureBDBM86519C21H25NO5371.4336 / 02.5Yes
2858172D structure6-AcDHMC19H23NO4329.3965 / 12.4Yes
3630562D structureCACOC27H27N3O6489.5287 / 13.1Yes
3926272D structureCHEMBL126243C32H37N5O5571.6786 / 52.3No
4267852D structureCHEMBL329996C34H38N6O5610.7156 / 62.4No

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