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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Sphingosine 1-phosphate receptor 3
Species	Homo sapiens (Human)
Gene	S1PR3
Synonym	Sphingosine 1-phosphate receptor Edg-3 S1P3 receptor S1P3 S1P receptor Edg-3 S1P receptor 3 Endothelial differentiation G-protein coupled receptor 3 endothelial differentiation G protein-coupled receptor 3 edg3 [ Show all ]
Disease	Breast cancer
Length	378
Amino acid sequence	MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
UniProt	Q99500
Protein Data Bank	N/A
GPCR-HGmod model	Q99500
3D structure model	This predicted structure model is from GPCR-EXP Q99500.
BioLiP	N/A
Therapeutic Target Database	T11241
ChEMBL	CHEMBL3892
IUPHAR	277
DrugBank	N/A

Ligand

Name	CYM50199
Molecular formula	C14H12BrCl2NO2
IUPAC name	2-bromo-3-[2-(2,4-dichlorophenoxy)ethoxy]-6-methylpyridine
Molecular weight	377.059
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.2
Synonyms	CHEBI:92299 SR-02000000306-1 2-bromo-3-[2-(2,4-dichlorophenoxy)ethoxy]-6-methyl-pyridine cid_44620895 SMR001828628 2-bromo-3-[2-(2,4-dichlorophenoxy)ethoxy]-6-methylpyridine BDBM75604 SR-02000000306 CHEMBL1722064 3-[2-[2,4-bis(chloranyl)phenoxy]ethoxy]-2-bromanyl-6-methyl-pyridine MLS003115020 [ Show all ]
Inchi Key	AGOUWTBVEAKQIJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H12BrCl2NO2/c1-9-2-4-13(14(15)18-9)20-7-6-19-12-5-3-10(16)8-11(12)17/h2-5,8H,6-7H2,1H3
PubChem CID	44620895
ChEMBL	CHEMBL1722064
IUPHAR	N/A
BindingDB	75604
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
EC50	<50000.0 nM	, PubChem BioAssay data set	BindingDB,ChEMBL

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