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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Putative P2Y purinoceptor 10
Species	Homo sapiens (Human)
Gene	P2RY10
Synonym	P2Y-like receptor P2RY10 purinergic receptor P2Y purinergic receptor P2Y, G-protein coupled 10 purinergic receptor P2Y10 P2Y10 [ Show all ]
Disease	N/A
Length	339
Amino acid sequence	MANLDKYTETFKMGSNSTSTAEIYCNVTNVKFQYSLYATTYILIFIPGLLANSAALWVLCRFISKKNKAIIFMINLSVADLAHVLSLPLRIYYYISHHWPFQRALCLLCFYLKYLNMYASICFLTCISLQRCFFLLKPFRARDWKRRYDVGISAAIWIVVGTACLPFPILRSTDLNNNKSCFADLGYKQMNAVALVGMITVAELAGFVIPVIIIAWCTWKTTISLRQPPMAFQGISERQKALRMVFMCAAVFFICFTPYHINFIFYTMVKETIISSCPVVRIALYFHPFCLCLASLCCLLDPILYYFMASEFRDQLSRHGSSVTRSRLMSKESGSSMIG
UniProt	O00398
Protein Data Bank	N/A
GPCR-HGmod model	O00398
3D structure model	This predicted structure model is from GPCR-EXP O00398.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3562166
IUPHAR	165
DrugBank	N/A

Ligand

Name	CHEMBL3577149
Molecular formula	C22H42NO8P
IUPAC name	(2S)-2-amino-3-[3-[(Z)-hexadec-9-enoyl]oxypropoxy-hydroxyphosphoryl]oxypropanoic acid
Molecular weight	479.551
Hydrogen bond acceptor	9
Hydrogen bond donor	3
XlogP	2.0
Synonyms	BDBM50096355
Inchi Key	CZDMDSMYEOVSIH-AQWUKCDYSA-N
Inchi ID	InChI=1S/C22H42NO8P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-21(24)29-17-15-18-30-32(27,28)31-19-20(23)22(25)26/h7-8,20H,2-6,9-19,23H2,1H3,(H,25,26)(H,27,28)/b8-7-/t20-/m0/s1
PubChem CID	122177497
ChEMBL	CHEMBL3577149
IUPHAR	N/A
BindingDB	50096355
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	57.54 nM	PMID25970039	ChEMBL
EC50	58.0 nM	PMID25970039	BindingDB,ChEMBL

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