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BioLiP
Download all results in tab-seperated text for 903398 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    61801 1xhv:D (2.5) BS06 MN 3.1.21.4 GO:0003677 ... P17743 15476804
    61802 1xhv:D (2.5) BS07 MN 3.1.21.4 GO:0003677 ... P17743 15476804
    61803 1xhv:D (2.5) BS08 MN 3.1.21.4 GO:0003677 ... P17743 15476804
    61804 1xhy:A (1.85) BS01 KAI ? GO:0015276 ... P19491 15591246 MOAD: Ki=624nM
    PDBbind: -logKd/Ki=6.18, Ki=662nM
    BindingDB: EC50=380000nM, Ki=3690nM
    61805 1xhz:A (2.7) BS01 dna 2.7.7.7
    3.1.11.-
    GO:0000166 ... P03680 15546620
    61806 1xhz:B (2.7) BS01 dna 2.7.7.7
    3.1.11.-
    GO:0000166 ... P03680 15546620
    61807 1xhz:C (2.7) BS01 dna 2.7.7.7
    3.1.11.-
    GO:0000166 ... P03680 15546620
    61808 1xhz:D (2.7) BS01 dna 2.7.7.7
    3.1.11.-
    GO:0000166 ... P03680 15546620
    61809 1xi1:A (2.2) BS01 dna 2.7.7.7
    3.1.11.-
    GO:0000166 ... P03680 15608377
    61810 1xi1:A (2.2) BS02 MG 2.7.7.7
    3.1.11.-
    GO:0000166 ... P03680 15608377
    61811 1xi1:B (2.2) BS01 dna 2.7.7.7
    3.1.11.-
    GO:0000166 ... P03680 15608377
    61812 1xi1:B (2.2) BS02 MG 2.7.7.7
    3.1.11.-
    GO:0000166 ... P03680 15608377
    61813 1xi2:A (1.5) BS01 ZN 1.10.5.1 GO:0001512 ... P16083 16129418
    61814 1xi2:A (1.5) BS02 FAD 1.10.5.1 GO:0001512 ... P16083 16129418
    61815 1xi2:A (1.5) BS03 CB1 1.10.5.1 GO:0001512 ... P16083 16129418 MOAD: ic50<1uM
    61816 1xi2:A (1.5) BS04 CB1 1.10.5.1 GO:0001512 ... P16083 16129418 MOAD: ic50<1uM
    61817 1xi2:B (1.5) BS01 ZN 1.10.5.1 GO:0001512 ... P16083 16129418
    61818 1xi2:B (1.5) BS02 ZN 1.10.5.1 GO:0001512 ... P16083 16129418
    61819 1xi2:B (1.5) BS03 FAD 1.10.5.1 GO:0001512 ... P16083 16129418
    61820 1xi2:B (1.5) BS04 CB1 1.10.5.1 GO:0001512 ... P16083 16129418 MOAD: ic50<1uM
    61821 1xi9:A (2.33) BS01 PLP ? GO:0008483 ... Q9P9M8 N/A
    61822 1xi9:B (2.33) BS01 PLP ? GO:0008483 ... Q9P9M8 N/A
    61823 1xi9:C (2.33) BS01 PLP ? GO:0008483 ... Q9P9M8 N/A
    61824 1xi9:D (2.33) BS01 PLP ? GO:0008483 ... Q9P9M8 N/A
    61825 1xib:A (1.6) BS01 MN 5.3.1.5 GO:0000287 ... P24300 15299449
    61826 1xib:A (1.6) BS02 MN 5.3.1.5 GO:0000287 ... P24300 15299449
    61827 1xic:A (1.6) BS01 XLS 5.3.1.5 GO:0000287 ... P24300 15299449
    61828 1xic:A (1.6) BS02 MN 5.3.1.5 GO:0000287 ... P24300 15299449
    61829 1xic:A (1.6) BS03 MN 5.3.1.5 GO:0000287 ... P24300 15299449
    61830 1xid:A (1.7) BS01 MN 5.3.1.5 GO:0000287 ... P24300 15299449
    61831 1xid:A (1.7) BS02 MN 5.3.1.5 GO:0000287 ... P24300 15299449
    61832 1xid:A (1.7) BS03 ASC 5.3.1.5 GO:0000287 ... P24300 15299449
    61833 1xie:A (1.7) BS01 ASO 5.3.1.5 GO:0000287 ... P24300 15299449
    61834 1xie:A (1.7) BS02 MN 5.3.1.5 GO:0000287 ... P24300 15299449
    61835 1xie:A (1.7) BS03 MN 5.3.1.5 GO:0000287 ... P24300 15299449
    61836 1xif:A (1.6) BS01 GLC 5.3.1.5 GO:0000287 ... P24300 15299449
    61837 1xif:A (1.6) BS02 MN 5.3.1.5 GO:0000287 ... P24300 15299449
    61838 1xif:A (1.6) BS03 MN 5.3.1.5 GO:0000287 ... P24300 15299449
    61839 1xig:A (1.7) BS01 XYL 5.3.1.5 GO:0000287 ... P24300 15299449
    61840 1xig:A (1.7) BS02 MN 5.3.1.5 GO:0000287 ... P24300 15299449
    61841 1xig:A (1.7) BS03 MN 5.3.1.5 GO:0000287 ... P24300 15299449
    61842 1xih:A (1.7) BS01 SOR 5.3.1.5 GO:0000287 ... P24300 15299449
    61843 1xih:A (1.7) BS02 MN 5.3.1.5 GO:0000287 ... P24300 15299449
    61844 1xii:A (1.7) BS01 XUL 5.3.1.5 GO:0000287 ... P24300 15299449
    61845 1xii:A (1.7) BS02 MN 5.3.1.5 GO:0000287 ... P24300 15299449
    61846 1xii:A (1.7) BS03 MN 5.3.1.5 GO:0000287 ... P24300 15299449
    61847 1xij:A (1.7) BS01 MN 5.3.1.5 GO:0000287 ... P24300 15299449
    61848 1xik:A (1.7) BS01 FE2 1.17.4.1 GO:0004748 ... P69924 8805591
    61849 1xik:A (1.7) BS02 FE2 1.17.4.1 GO:0004748 ... P69924 8805591
    61850 1xik:B (1.7) BS01 FE2 1.17.4.1 GO:0004748 ... P69924 8805591
    61851 1xik:B (1.7) BS02 FE2 1.17.4.1 GO:0004748 ... P69924 8805591
    61852 1xil:A (1.53) BS01 MN 1.15.1.1 GO:0004784 ... P04179 16150974
    61853 1xil:B (1.53) BS01 MN 1.15.1.1 GO:0004784 ... P04179 16150974
    61854 1xim:A (2.2) BS01 XYL 5.3.1.5 GO:0000287 ... P12851 1540579
    61855 1xim:A (2.2) BS02 CO 5.3.1.5 GO:0000287 ... P12851 1540579
    61856 1xim:A (2.2) BS03 CO 5.3.1.5 GO:0000287 ... P12851 1540579
    61857 1xim:B (2.2) BS01 XYL 5.3.1.5 GO:0000287 ... P12851 1540579
    61858 1xim:B (2.2) BS02 CO 5.3.1.5 GO:0000287 ... P12851 1540579
    61859 1xim:B (2.2) BS03 CO 5.3.1.5 GO:0000287 ... P12851 1540579
    61860 1xim:C (2.2) BS01 XYL 5.3.1.5 GO:0000287 ... P12851 1540579
    61861 1xim:C (2.2) BS02 CO 5.3.1.5 GO:0000287 ... P12851 1540579
    61862 1xim:C (2.2) BS03 CO 5.3.1.5 GO:0000287 ... P12851 1540579
    61863 1xim:D (2.2) BS01 XYL 5.3.1.5 GO:0000287 ... P12851 1540579
    61864 1xim:D (2.2) BS02 CO 5.3.1.5 GO:0000287 ... P12851 1540579
    61865 1xim:D (2.2) BS03 CO 5.3.1.5 GO:0000287 ... P12851 1540579
    61866 1xin:A (2.4) BS01 XYL 5.3.1.5 GO:0000287 ... P12851 1610791
    61867 1xin:A (2.4) BS02 MG 5.3.1.5 GO:0000287 ... P12851 1610791
    61868 1xin:B (2.4) BS01 XYL 5.3.1.5 GO:0000287 ... P12851 1610791
    61869 1xin:B (2.4) BS02 MG 5.3.1.5 GO:0000287 ... P12851 1610791
    61870 1xin:C (2.4) BS01 XYL 5.3.1.5 GO:0000287 ... P12851 1610791
    61871 1xin:C (2.4) BS02 MG 5.3.1.5 GO:0000287 ... P12851 1610791
    61872 1xin:D (2.4) BS01 XYL 5.3.1.5 GO:0000287 ... P12851 1610791
    61873 1xin:D (2.4) BS02 MG 5.3.1.5 GO:0000287 ... P12851 1610791
    61874 1xio:A (2.0) BS01 RET ? GO:0005216 ... Q8YSC4 15459346
    61875 1xis:A (1.6) BS01 MN 5.3.1.5 GO:0000287 ... P24300 2006134
    61876 1xis:A (1.6) BS02 MN 5.3.1.5 GO:0000287 ... P24300 2006134
    61877 1xiu:A (2.5) BS01 peptide ? GO:0003677 ... Q8T5C6 16274693
    61878 1xiu:A (2.5) BS02 9CR ? GO:0003677 ... Q8T5C6 16274693
    61879 1xiu:B (2.5) BS01 peptide ? GO:0003677 ... Q8T5C6 16274693
    61880 1xiu:B (2.5) BS02 9CR ? GO:0003677 ... Q8T5C6 16274693
    61881 1xiv:A (1.7) BS01 RB2 1.1.1.27 GO:0003824 ... Q27743 15978953
    61882 1xj0:A (1.7) BS01 GDP 3.6.5.2 GO:0003924 ... P01112 N/A
    61883 1xj2:A (2.0) BS01 HEM 2.7.13.3 GO:0006355 ... P23222 15779889
    61884 1xj2:A (2.0) BS02 CMO 2.7.13.3 GO:0006355 ... P23222 15779889
    61885 1xj3:A (1.9) BS01 HEM 2.7.13.3 GO:0006355 ... P23222 15779889
    61886 1xj4:A (1.8) BS01 HEM 2.7.13.3 GO:0006355 ... P23222 15779889
    61887 1xj4:A (1.8) BS02 CMO 2.7.13.3 GO:0006355 ... P23222 15779889
    61888 1xj4:B (1.8) BS01 HEM 2.7.13.3 GO:0006355 ... P23222 15779889
    61889 1xj6:A (1.9) BS01 HEM 2.7.13.3 GO:0006355 ... P23222 15779889
    61890 1xj6:B (1.9) BS01 HEM 2.7.13.3 GO:0006355 ... P23222 15779889
    61891 1xj7:A (2.7) BS01 peptide ? N/A P10275 15563469
    61892 1xj7:A (2.7) BS02 DHT ? N/A P10275 15563469 BindingDB: IC50=>10000nM, EC50=6nM, Ki=0.2nM
    61893 1xjb:A (1.9) BS01 ACT 1.-.-.-
    1.1.1.112
    1.1.1.209
    1.1.1.357
    1.1.1.53
    1.1.1.62
    1.3.1.20
    GO:0004032 ... P52895 15929998
    61894 1xjb:A (1.9) BS02 ACT 1.-.-.-
    1.1.1.112
    1.1.1.209
    1.1.1.357
    1.1.1.53
    1.1.1.62
    1.3.1.20
    GO:0004032 ... P52895 15929998
    61895 1xjb:A (1.9) BS03 NAP 1.-.-.-
    1.1.1.112
    1.1.1.209
    1.1.1.357
    1.1.1.53
    1.1.1.62
    1.3.1.20
    GO:0004032 ... P52895 15929998 MOAD: Kd=0.88uM
    61896 1xjb:B (1.9) BS01 ACT 1.-.-.-
    1.1.1.112
    1.1.1.209
    1.1.1.357
    1.1.1.53
    1.1.1.62
    1.3.1.20
    GO:0004032 ... P52895 15929998
    61897 1xjb:B (1.9) BS02 NAP 1.-.-.-
    1.1.1.112
    1.1.1.209
    1.1.1.357
    1.1.1.53
    1.1.1.62
    1.3.1.20
    GO:0004032 ... P52895 15929998 MOAD: Kd=0.88uM
    61898 1xjd:A (2.0) BS01 STU 2.7.11.13 GO:0004672 ... Q04759 15364937 MOAD: Ki=0.33nM
    PDBbind: -logKd/Ki=9.48, Ki=0.33nM
    61899 1xje:A (1.9) BS01 GDP 1.17.4.1 GO:0000166 ... O33839 15475969
    61900 1xje:A (1.9) BS02 TTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61901 1xje:A (1.9) BS03 TTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61902 1xje:B (1.9) BS01 TTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61903 1xje:B (1.9) BS02 GDP 1.17.4.1 GO:0000166 ... O33839 15475969
    61904 1xje:B (1.9) BS03 TTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61905 1xjf:A (2.4) BS01 DTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61906 1xjf:A (2.4) BS02 DTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61907 1xjf:B (2.4) BS01 DTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61908 1xjf:B (2.4) BS02 DTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61909 1xjg:A (2.5) BS01 UDP 1.17.4.1 GO:0000166 ... O33839 15475969
    61910 1xjg:A (2.5) BS02 DTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61911 1xjg:A (2.5) BS03 DTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61912 1xjg:B (2.5) BS01 DTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61913 1xjg:B (2.5) BS02 UDP 1.17.4.1 GO:0000166 ... O33839 15475969
    61914 1xjg:B (2.5) BS03 DTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61915 1xji:A (2.2) BS01 RET ? GO:0005216 ... P02945 15689517
    61916 1xji:A (2.2) BS02 CPS ? GO:0005216 ... P02945 15689517
    61917 1xjj:A (1.86) BS01 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    61918 1xjj:A (1.86) BS02 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    61919 1xjj:A (1.86) BS03 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    61920 1xjj:B (1.86) BS01 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    61921 1xjj:B (1.86) BS02 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    61922 1xjj:B (1.86) BS03 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    61923 1xjk:A (2.12) BS01 ADP 1.17.4.1 GO:0000166 ... O33839 15475969
    61924 1xjk:A (2.12) BS02 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    61925 1xjk:A (2.12) BS03 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    61926 1xjk:B (2.12) BS01 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    61927 1xjk:B (2.12) BS02 ADP 1.17.4.1 GO:0000166 ... O33839 15475969
    61928 1xjk:B (2.12) BS03 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    61929 1xjl:A (2.59) BS01 CA ? GO:0001525 ... P07355 N/A
    61930 1xjl:A (2.59) BS02 CA ? GO:0001525 ... P07355 N/A
    61931 1xjl:A (2.59) BS03 CA ? GO:0001525 ... P07355 N/A
    61932 1xjl:A (2.59) BS04 CA ? GO:0001525 ... P07355 N/A
    61933 1xjl:A (2.59) BS05 CA ? GO:0001525 ... P07355 N/A
    61934 1xjl:A (2.59) BS06 CA ? GO:0001525 ... P07355 N/A
    61935 1xjl:A (2.59) BS07 CA ? GO:0001525 ... P07355 N/A
    61936 1xjl:B (2.59) BS01 CA ? GO:0001525 ... P07355 N/A
    61937 1xjl:B (2.59) BS02 CA ? GO:0001525 ... P07355 N/A
    61938 1xjl:B (2.59) BS03 CA ? GO:0001525 ... P07355 N/A
    61939 1xjl:B (2.59) BS04 CA ? GO:0001525 ... P07355 N/A
    61940 1xjl:B (2.59) BS05 CA ? GO:0001525 ... P07355 N/A
    61941 1xjl:B (2.59) BS06 CA ? GO:0001525 ... P07355 N/A
    61942 1xjl:B (2.59) BS07 CA ? GO:0001525 ... P07355 N/A
    61943 1xjm:A (2.4) BS01 TTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61944 1xjm:A (2.4) BS02 TTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61945 1xjm:A (2.4) BS03 TTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61946 1xjm:B (2.4) BS01 TTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61947 1xjm:B (2.4) BS02 TTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61948 1xjm:B (2.4) BS03 TTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61949 1xjn:A (2.25) BS01 CDP 1.17.4.1 GO:0000166 ... O33839 15475969
    61950 1xjn:A (2.25) BS02 DTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61951 1xjn:A (2.25) BS03 DTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61952 1xjn:B (2.25) BS01 DTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61953 1xjn:B (2.25) BS02 CDP 1.17.4.1 GO:0000166 ... O33839 15475969
    61954 1xjn:B (2.25) BS03 DTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61955 1xjn:C (2.25) BS01 CDP 1.17.4.1 GO:0000166 ... O33839 15475969
    61956 1xjn:C (2.25) BS02 DTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61957 1xjn:C (2.25) BS03 DTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61958 1xjn:D (2.25) BS01 DTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61959 1xjn:D (2.25) BS02 DTP 1.17.4.1 GO:0000166 ... O33839 15475969
    61960 1xjn:D (2.25) BS03 CDP 1.17.4.1 GO:0000166 ... O33839 15475969
    61961 1xjo:A (1.75) BS01 ZN 3.4.11.24 GO:0004177 ... P80561 9048953
    61962 1xjo:A (1.75) BS02 ZN 3.4.11.24 GO:0004177 ... P80561 9048953
    61963 1xjo:A (1.75) BS03 PO4 3.4.11.24 GO:0004177 ... P80561 9048953
    61964 1xjo:A (1.75) BS04 CA 3.4.11.24 GO:0004177 ... P80561 9048953
    61965 1xjq:A (2.06) BS01 ADP 2.7.1.25
    2.7.7.4
    GO:0000103 ... O43252 15755455
    61966 1xjq:B (2.06) BS01 ADP 2.7.1.25
    2.7.7.4
    GO:0000103 ... O43252 15755455
    61967 1xjq:B (2.06) BS02 ADP 2.7.1.25
    2.7.7.4
    GO:0000103 ... O43252 15755455
    61968 1xjs:A (-1.00) BS01 ZN 2.-.-.- GO:0005506 ... O32163 N/A
    61969 1xjv:A (1.73) BS01 dna ? GO:0000723 ... Q9NUX5 15558049 PDBbind: Kd=9.2nM
    61970 1xjw:A (2.71) BS01 PAL 2.1.3.2 GO:0004070 ... P0A786 15890205
    61971 1xjw:B (2.71) BS01 ZN ? GO:0005515 ... P0A7F3 15890205
    61972 1xjw:C (2.71) BS01 PAL 2.1.3.2 GO:0004070 ... P0A786 15890205
    61973 1xjw:D (2.71) BS01 ZN ? GO:0005515 ... P0A7F3 15890205
    61974 1xjz:A (1.88) BS01 HEM 1.14.14.18 GO:0004392 ... P09601 15690204
    61975 1xjz:B (1.88) BS01 HEM 1.14.14.18 GO:0004392 ... P09601 15690204
    61976 1xk0:A (2.18) BS01 HEM 1.14.14.18 GO:0004392 ... P09601 15690204
    61977 1xk0:B (2.18) BS01 HEM 1.14.14.18 GO:0004392 ... P09601 15690204
    61978 1xk1:A (2.08) BS01 HEM 1.14.14.18 GO:0004392 ... P09601 15690204
    61979 1xk1:B (2.08) BS01 HEM 1.14.14.18 GO:0004392 ... P09601 15690204
    61980 1xk2:A (2.2) BS01 HEM 1.14.14.18 GO:0004392 ... P09601 15525643
    61981 1xk2:B (2.2) BS01 HEM 1.14.14.18 GO:0004392 ... P09601 15525643
    61982 1xk3:A (2.08) BS01 HEM 1.14.14.18 GO:0004392 ... P09601 15525643
    61983 1xk3:B (2.08) BS01 HEM 1.14.14.18 GO:0004392 ... P09601 15525643
    61984 1xk4:A (1.8) BS01 CA ? GO:0002523 ... P05109 17553524
    61985 1xk4:A (1.8) BS02 CA ? GO:0002523 ... P05109 17553524
    61986 1xk4:B (1.8) BS01 CA ? GO:0002523 ... P05109 17553524
    61987 1xk4:B (1.8) BS02 CA ? GO:0002523 ... P05109 17553524
    61988 1xk4:C (1.8) BS01 CA ? GO:0002523 ... P06702 17553524
    61989 1xk4:C (1.8) BS02 CA ? GO:0002523 ... P06702 17553524
    61990 1xk4:D (1.8) BS01 CA ? GO:0002523 ... P06702 17553524
    61991 1xk4:D (1.8) BS02 CA ? GO:0002523 ... P06702 17553524
    61992 1xk4:E (1.8) BS01 CA ? GO:0002523 ... P05109 17553524
    61993 1xk4:E (1.8) BS02 CA ? GO:0002523 ... P05109 17553524
    61994 1xk4:F (1.8) BS01 CA ? GO:0002523 ... P05109 17553524
    61995 1xk4:F (1.8) BS02 CA ? GO:0002523 ... P05109 17553524
    61996 1xk4:G (1.8) BS01 CA ? GO:0002523 ... P06702 17553524
    61997 1xk4:G (1.8) BS02 CA ? GO:0002523 ... P06702 17553524
    61998 1xk4:H (1.8) BS01 CA ? GO:0002523 ... P06702 17553524
    61999 1xk4:H (1.8) BS02 CA ? GO:0002523 ... P06702 17553524
    62000 1xk4:I (1.8) BS01 CA ? GO:0002523 ... P05109 17553524

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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