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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 903398 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    29001 1les:C (1.9) BS02 CA ? GO:0030246 ... P02870 7592736
    29002 1les:C (1.9) BS03 MN ? GO:0030246 ... P02870 7592736
    29003 1les:D (1.9) BS01 GLC ? GO:0030246 ... P02870 7592736
    29004 1lev:A (2.15) BS01 F6P 3.1.3.11 GO:0005737 ... P00636 12781194
    29005 1lev:A (2.15) BS02 MN 3.1.3.11 GO:0005737 ... P00636 12781194
    29006 1lev:A (2.15) BS03 MN 3.1.3.11 GO:0005737 ... P00636 12781194
    29007 1lev:A (2.15) BS04 CLI 3.1.3.11 GO:0005737 ... P00636 12781194 MOAD: ic50=2.5uM
    PDBbind: -logKd/Ki=5.60, IC50=2.5uM
    29008 1lev:F (2.15) BS01 F6P 3.1.3.11 GO:0005737 ... P00636 12781194
    29009 1lev:F (2.15) BS02 MN 3.1.3.11 GO:0005737 ... P00636 12781194
    29010 1lev:F (2.15) BS03 MN 3.1.3.11 GO:0005737 ... P00636 12781194
    29011 1lev:F (2.15) BS04 CLI 3.1.3.11 GO:0005737 ... P00636 12781194 MOAD: ic50=2.5uM
    29012 1lew:A (2.3) BS01 peptide 2.7.11.24 GO:0000077 ... P47811 12086621
    29013 1lez:A (2.3) BS01 peptide 2.7.11.24 GO:0000077 ... P47811 12086621
    29014 1lf0:A (1.7) BS01 MG 3.6.5.2 GO:0003924 ... P01112 12213964
    29015 1lf0:A (1.7) BS02 CA 3.6.5.2 GO:0003924 ... P01112 12213964
    29016 1lf0:A (1.7) BS03 CA 3.6.5.2 GO:0003924 ... P01112 12213964
    29017 1lf0:A (1.7) BS04 GNP 3.6.5.2 GO:0003924 ... P01112 12213964
    29018 1lf2:A (1.8) BS01 R37 3.4.23.39 GO:0004190 ... P46925 12454457 PDBbind: -logKd/Ki=7.52, Ki=30nM
    29019 1lf3:A (2.7) BS01 EH5 3.4.23.39 GO:0004190 ... P46925 12614616 PDBbind: -logKd/Ki=7.00, Ki=100nM
    29020 1lf5:A (1.7) BS01 GDP 3.6.5.2 GO:0003924 ... P01112 12213964
    29021 1lf8:A (2.3) BS01 peptide ? GO:0005802 ... Q9NZ52 12032548
    29022 1lf8:B (2.3) BS01 peptide ? GO:0005802 ... Q9NZ52 12032548
    29023 1lf8:C (2.3) BS01 peptide ? GO:0005802 ... Q9NZ52 12032548
    29024 1lf8:D (2.3) BS01 peptide ? GO:0005802 ... Q9NZ52 12032548
    29025 1lf9:A (2.2) BS01 GLC 3.2.1.3 GO:0003824 ... O85672 12614608
    29026 1lf9:A (2.2) BS02 AC1 3.2.1.3 GO:0003824 ... O85672 12614608
    29027 1lf9:B (2.2) BS01 GLC 3.2.1.3 GO:0003824 ... O85672 12614608
    29028 1lf9:B (2.2) BS02 AC1 3.2.1.3 GO:0003824 ... O85672 12614608
    29029 1lfa:A (1.8) BS01 MN ? N/A P20701 7479767
    29030 1lfa:B (1.8) BS01 MN ? N/A P20701 7479767
    29031 1lfd:B (2.1) BS01 MG 3.6.5.2 GO:0003924 ... P01112 9628477
    29032 1lfd:B (2.1) BS02 GNP 3.6.5.2 GO:0003924 ... P01112 9628477
    29033 1lfd:D (2.1) BS01 MG 3.6.5.2 GO:0003924 ... P01112 9628477
    29034 1lfd:D (2.1) BS02 GNP 3.6.5.2 GO:0003924 ... P01112 9628477
    29035 1lfg:A (2.2) BS01 FE 3.4.21.- GO:0001503 ... P02788 15299793
    29036 1lfg:A (2.2) BS02 FE 3.4.21.- GO:0001503 ... P02788 15299793
    29037 1lfg:A (2.2) BS03 CO3 3.4.21.- GO:0001503 ... P02788 15299793
    29038 1lfg:A (2.2) BS04 CO3 3.4.21.- GO:0001503 ... P02788 15299793
    29039 1lfi:A (2.1) BS01 CU 3.4.21.- GO:0001503 ... P02788 1581307
    29040 1lfi:A (2.1) BS02 CU 3.4.21.- GO:0001503 ... P02788 1581307
    29041 1lfi:A (2.1) BS03 CO3 3.4.21.- GO:0001503 ... P02788 1581307
    29042 1lfi:A (2.1) BS04 CO3 3.4.21.- GO:0001503 ... P02788 1581307
    29043 1lfk:A (1.7) BS01 HEM 1.14.-.- GO:0004497 ... Q8RN04 12207020
    29044 1lfl:A (2.7) BS01 HEM ? GO:0004601 ... P69905 12077435
    29045 1lfl:B (2.7) BS01 HEM ? GO:0004601 ... P68871 12077435
    29046 1lfl:C (2.7) BS01 HEM ? GO:0004601 ... P69905 12077435
    29047 1lfl:D (2.7) BS01 HEM ? GO:0004601 ... P68871 12077435
    29048 1lfl:P (2.7) BS01 HEM ? GO:0004601 ... P69905 12077435
    29049 1lfl:Q (2.7) BS01 HEM ? GO:0004601 ... P68871 12077435
    29050 1lfl:R (2.7) BS01 HEM ? GO:0004601 ... P69905 12077435
    29051 1lfl:S (2.7) BS01 HEM ? GO:0004601 ... P68871 12077435
    29052 1lfm:A (1.5) BS01 COH ? GO:0005739 ... P81459 12084923
    29053 1lfm:B (1.5) BS01 COH ? GO:0005739 ... P81459 12084923
    29054 1lfo:A (2.3) BS01 OLA ? GO:0003682 ... P02692 9054409 MOAD: Kd~2uM
    PDBbind: -logKd/Ki=6.70, Kd~0.2uM
    BindingDB: Ki=2900nM
    29055 1lfo:A (2.3) BS02 OLA ? GO:0003682 ... P02692 9054409 MOAD: Kd~2uM
    PDBbind: -logKd/Ki=6.70, Kd~0.2uM
    BindingDB: Ki=2900nM
    29056 1lfo:A (2.3) BS03 BEO ? GO:0003682 ... P02692 9054409
    29057 1lfq:A (2.6) BS01 HEM ? GO:0004601 ... P69905 12077435
    29058 1lfq:B (2.6) BS01 HEM ? GO:0004601 ... P68871 12077435
    29059 1lft:A (2.6) BS01 HEM ? GO:0004601 ... P69905 12077435
    29060 1lft:B (2.6) BS01 HEM ? GO:0004601 ... P68871 12077435
    29061 1lfu:P (-1.00) BS01 dna ? GO:0000981 ... P41778 12409300
    29062 1lfu:P (-1.00) BS02 dna ? GO:0000981 ... P41778 12409300
    29063 1lfv:A (2.8) BS01 HEM ? GO:0004601 ... P69905 12077435
    29064 1lfv:B (2.8) BS01 HEM ? GO:0004601 ... P68871 12077435
    29065 1lfw:A (1.8) BS01 ZN 3.4.13.- GO:0005737 ... P45494 12176387
    29066 1lfw:A (1.8) BS02 ZN 3.4.13.- GO:0005737 ... P45494 12176387
    29067 1lfw:A (1.8) BS03 AEP 3.4.13.- GO:0005737 ... P45494 12176387
    29068 1lfy:A (3.3) BS01 HEM ? GO:0004601 ... P69905 12077435
    29069 1lfy:B (3.3) BS01 HEM ? GO:0004601 ... P68871 12077435
    29070 1lfz:A (3.1) BS01 HEM ? GO:0004601 ... P69905 12077435
    29071 1lfz:B (3.1) BS01 HEM ? GO:0004601 ... P68871 12077435
    29072 1lg5:A (1.75) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 12056894
    29073 1lg5:A (1.75) BS02 BME 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 12056894
    29074 1lg6:A (2.2) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 12056894
    29075 1lg6:A (2.2) BS02 SCN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 12056894 BindingDB: Ki=1600000nM
    29076 1lg9:A (2.0) BS01 HEM 1.14.-.- GO:0004497 ... Q8RN04 12207020
    29077 1lga:A (2.03) BS01 CA 1.11.1.14 GO:0000302 ... P49012 8440725
    29078 1lga:A (2.03) BS02 CA 1.11.1.14 GO:0000302 ... P49012 8440725
    29079 1lga:A (2.03) BS03 HEM 1.11.1.14 GO:0000302 ... P49012 8440725
    29080 1lga:B (2.03) BS01 CA 1.11.1.14 GO:0000302 ... P49012 8440725
    29081 1lga:B (2.03) BS02 CA 1.11.1.14 GO:0000302 ... P49012 8440725
    29082 1lga:B (2.03) BS03 HEM 1.11.1.14 GO:0000302 ... P49012 8440725
    29083 1lgb:A (3.3) BS01 MAN ? GO:0005515 ... P04122 8069634
    29084 1lgb:A (3.3) BS02 FUC ? GO:0005515 ... P04122 8069634
    29085 1lgb:A (3.3) BS03 MN ? GO:0005515 ... P04122 8069634
    29086 1lgb:A (3.3) BS04 CA ? GO:0005515 ... P04122 8069634
    29087 1lgb:B (3.3) BS01 MAN ? GO:0005515 ... P12307 8069634
    29088 1lgc:A (2.8) BS01 peptide ? GO:0005515 ... P04122 8069634
    29089 1lgc:A (2.8) BS02 MAN ? GO:0005515 ... P04122 8069634
    29090 1lgc:A (2.8) BS03 CA ? GO:0005515 ... P04122 8069634
    29091 1lgc:A (2.8) BS04 MN ? GO:0005515 ... P04122 8069634
    29092 1lgc:B (2.8) BS01 MAN ? GO:0005515 ... P12307 8069634
    29093 1lgc:C (2.8) BS01 MAN ? GO:0005515 ... P04122 8069634
    29094 1lgc:C (2.8) BS02 FUC ? GO:0005515 ... P04122 8069634
    29095 1lgc:C (2.8) BS03 CA ? GO:0005515 ... P04122 8069634
    29096 1lgc:C (2.8) BS04 MN ? GO:0005515 ... P04122 8069634
    29097 1lgc:D (2.8) BS01 MAN ? GO:0005515 ... P12307 8069634
    29098 1lgc:E (2.8) BS01 MAN ? GO:0005515 ... P04122 8069634
    29099 1lgc:E (2.8) BS02 CA ? GO:0005515 ... P04122 8069634
    29100 1lgc:E (2.8) BS03 MN ? GO:0005515 ... P04122 8069634
    29101 1lgc:F (2.8) BS01 MAN ? GO:0005515 ... P12307 8069634
    29102 1lgd:A (1.9) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 12056894
    29103 1lgd:A (1.9) BS02 BCT 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 12056894 BindingDB: Ki=85000000nM
    29104 1lgf:A (2.2) BS01 HEM 1.14.-.- GO:0004497 ... Q8RN04 12207020
    29105 1lgh:A (2.4) BS01 BCL ? GO:0005886 ... P97253 8736556
    29106 1lgh:A (2.4) BS02 BCL ? GO:0005886 ... P97253 8736556
    29107 1lgh:A (2.4) BS03 LYC ? GO:0005886 ... P97253 8736556
    29108 1lgh:A (2.4) BS04 BCL ? GO:0005886 ... P97253 8736556
    29109 1lgh:B (2.4) BS01 BCL ? GO:0005886 ... P95673 8736556
    29110 1lgh:B (2.4) BS02 BCL ? GO:0005886 ... P95673 8736556
    29111 1lgh:B (2.4) BS03 LYC ? GO:0005886 ... P95673 8736556
    29112 1lgh:B (2.4) BS04 BCL ? GO:0005886 ... P95673 8736556
    29113 1lgh:D (2.4) BS01 LYC ? GO:0005886 ... P97253 8736556
    29114 1lgh:D (2.4) BS02 BCL ? GO:0005886 ... P97253 8736556
    29115 1lgh:D (2.4) BS03 BCL ? GO:0005886 ... P97253 8736556
    29116 1lgh:D (2.4) BS04 LYC ? GO:0005886 ... P97253 8736556
    29117 1lgh:D (2.4) BS05 BCL ? GO:0005886 ... P97253 8736556
    29118 1lgh:E (2.4) BS01 BCL ? GO:0005886 ... P95673 8736556
    29119 1lgh:E (2.4) BS02 BCL ? GO:0005886 ... P95673 8736556
    29120 1lgh:E (2.4) BS03 LYC ? GO:0005886 ... P95673 8736556
    29121 1lgh:E (2.4) BS04 BCL ? GO:0005886 ... P95673 8736556
    29122 1lgh:G (2.4) BS01 BCL ? GO:0005886 ... P97253 8736556
    29123 1lgh:G (2.4) BS02 BCL ? GO:0005886 ... P97253 8736556
    29124 1lgh:G (2.4) BS03 LYC ? GO:0005886 ... P97253 8736556
    29125 1lgh:G (2.4) BS04 BCL ? GO:0005886 ... P97253 8736556
    29126 1lgh:H (2.4) BS01 BCL ? GO:0005886 ... P95673 8736556
    29127 1lgh:H (2.4) BS02 BCL ? GO:0005886 ... P95673 8736556
    29128 1lgh:H (2.4) BS03 LYC ? GO:0005886 ... P95673 8736556
    29129 1lgh:H (2.4) BS04 BCL ? GO:0005886 ... P95673 8736556
    29130 1lgh:J (2.4) BS01 LYC ? GO:0005886 ... P97253 8736556
    29131 1lgh:J (2.4) BS02 BCL ? GO:0005886 ... P97253 8736556
    29132 1lgh:J (2.4) BS03 BCL ? GO:0005886 ... P97253 8736556
    29133 1lgh:J (2.4) BS04 LYC ? GO:0005886 ... P97253 8736556
    29134 1lgh:J (2.4) BS05 BCL ? GO:0005886 ... P97253 8736556
    29135 1lgh:K (2.4) BS01 BCL ? GO:0005886 ... P95673 8736556
    29136 1lgh:K (2.4) BS02 BCL ? GO:0005886 ... P95673 8736556
    29137 1lgh:K (2.4) BS03 LYC ? GO:0005886 ... P95673 8736556
    29138 1lgh:K (2.4) BS04 BCL ? GO:0005886 ... P95673 8736556
    29139 1lgn:A (2.8) BS01 CA ? GO:0001849 ... P02743 9217261
    29140 1lgn:A (2.8) BS02 CA ? GO:0001849 ... P02743 9217261
    29141 1lgn:A (2.8) BS03 DA ? GO:0001849 ... P02743 9217261
    29142 1lgn:B (2.8) BS01 CA ? GO:0001849 ... P02743 9217261
    29143 1lgn:B (2.8) BS02 CA ? GO:0001849 ... P02743 9217261
    29144 1lgn:B (2.8) BS03 DA ? GO:0001849 ... P02743 9217261
    29145 1lgn:C (2.8) BS01 CA ? GO:0001849 ... P02743 9217261
    29146 1lgn:C (2.8) BS02 CA ? GO:0001849 ... P02743 9217261
    29147 1lgn:C (2.8) BS03 DA ? GO:0001849 ... P02743 9217261
    29148 1lgn:D (2.8) BS01 CA ? GO:0001849 ... P02743 9217261
    29149 1lgn:D (2.8) BS02 CA ? GO:0001849 ... P02743 9217261
    29150 1lgn:D (2.8) BS03 DA ? GO:0001849 ... P02743 9217261
    29151 1lgn:E (2.8) BS01 CA ? GO:0001849 ... P02743 9217261
    29152 1lgn:E (2.8) BS02 CA ? GO:0001849 ... P02743 9217261
    29153 1lgn:E (2.8) BS03 DA ? GO:0001849 ... P02743 9217261
    29154 1lgp:A (2.0) BS01 WO4 2.3.2.27 N/A Q96EP1 12121644
    29155 1lgr:A (2.79) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29156 1lgr:A (2.79) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29157 1lgr:A (2.79) BS03 AMP 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29158 1lgr:B (2.79) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29159 1lgr:B (2.79) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29160 1lgr:B (2.79) BS03 AMP 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29161 1lgr:C (2.79) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29162 1lgr:C (2.79) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29163 1lgr:C (2.79) BS03 AMP 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29164 1lgr:D (2.79) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29165 1lgr:D (2.79) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29166 1lgr:D (2.79) BS03 AMP 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29167 1lgr:E (2.79) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29168 1lgr:E (2.79) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29169 1lgr:E (2.79) BS03 AMP 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29170 1lgr:F (2.79) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29171 1lgr:F (2.79) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29172 1lgr:F (2.79) BS03 AMP 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29173 1lgr:G (2.79) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29174 1lgr:G (2.79) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29175 1lgr:G (2.79) BS03 AMP 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29176 1lgr:H (2.79) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29177 1lgr:H (2.79) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29178 1lgr:H (2.79) BS03 AMP 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29179 1lgr:I (2.79) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29180 1lgr:I (2.79) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29181 1lgr:I (2.79) BS03 AMP 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29182 1lgr:J (2.79) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29183 1lgr:J (2.79) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29184 1lgr:J (2.79) BS03 AMP 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29185 1lgr:K (2.79) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29186 1lgr:K (2.79) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29187 1lgr:K (2.79) BS03 AMP 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29188 1lgr:L (2.79) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29189 1lgr:L (2.79) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29190 1lgr:L (2.79) BS03 AMP 6.3.1.2 GO:0003824 ... P0A1P6 7727369
    29191 1lgt:A (1.7) BS01 FE2 1.13.11.39 GO:0003824 ... P47228 12415290
    29192 1lgt:A (1.7) BS02 FE2 1.13.11.39 GO:0003824 ... P47228 12415290
    29193 1lgt:A (1.7) BS03 BP3 1.13.11.39 GO:0003824 ... P47228 12415290 MOAD: Kd=0.8uM
    PDBbind: -logKd/Ki=6.10, Kd=0.8uM
    29194 1lgt:A (1.7) BS04 BP3 1.13.11.39 GO:0003824 ... P47228 12415290 MOAD: Kd=0.8uM
    PDBbind: -logKd/Ki=6.10, Kd=0.8uM
    29195 1lgw:A (1.85) BS01 1AN 3.2.1.17 GO:0003796 ... P00720 12217695 MOAD: Kd=100uM
    PDBbind: -logKd/Ki=4.00, Kd=100uM
    29196 1lgx:A (1.9) BS01 5AN 3.2.1.17 GO:0003796 ... P00720 12217695
    29197 1lh0:A (2.0) BS01 PRP 2.4.2.10 GO:0000287 ... P08870 22531064
    29198 1lh0:B (2.0) BS01 PRP 2.4.2.10 GO:0000287 ... P08870 22531064
    29199 1lh1:A (2.0) BS01 HEM ? GO:0005344 ... P02240 N/A
    29200 1lh2:A (2.0) BS01 HEM ? GO:0005344 ... P02240 N/A

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218