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BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    13001 1i5q:A (1.83) BS01 MOX 3.5.2.6 GO:0008800 ... P00811 11434768
    13002 1i5q:B (1.83) BS01 MOX 3.5.2.6 GO:0008800 ... P00811 11434768
    13003 1i5r:A (1.6) BS01 HYC 1.1.1.51
    1.1.1.62
    GO:0003824 ... P14061 12223444 MOAD: Ki=3nM
    PDBbind: -logKd/Ki=8.52, Ki=3.0nM
    BindingDB: IC50=52nM, Ki=3nM
    13004 1i5t:A (-1.00) BS01 HEC ? GO:0005515 ... P00004 11941512
    13005 1i5z:A (1.9) BS01 CMP ? GO:0003677 ... P0ACJ8 N/A
    13006 1i5z:A (1.9) BS02 CMP ? GO:0003677 ... P0ACJ8 N/A
    13007 1i5z:B (1.9) BS01 CMP ? GO:0003677 ... P0ACJ8 N/A
    13008 1i6h:A (3.3) BS01 dna 2.7.7.6 GO:0000428 ... P04050 11313499
    13009 1i6h:A (3.3) BS02 rna 2.7.7.6 GO:0000428 ... P04050 11313499
    13010 1i6h:A (3.3) BS03 MG 2.7.7.6 GO:0000428 ... P04050 11313499
    13011 1i6h:A (3.3) BS04 ZN 2.7.7.6 GO:0000428 ... P04050 11313499
    13012 1i6h:B (3.3) BS01 dna 2.7.7.6 GO:0000428 ... P08518 11313499
    13013 1i6h:B (3.3) BS02 rna 2.7.7.6 GO:0000428 ... P08518 11313499
    13014 1i6h:B (3.3) BS03 ZN 2.7.7.6 GO:0000428 ... P08518 11313499
    13015 1i6h:C (3.3) BS01 ZN 2.7.7.6 GO:0000428 ... P16370 11313499
    13016 1i6h:I (3.3) BS01 ZN 2.7.7.6 GO:0000428 ... P27999 11313499
    13017 1i6h:I (3.3) BS02 ZN 2.7.7.6 GO:0000428 ... P27999 11313499
    13018 1i6h:J (3.3) BS01 ZN 2.7.7.6 GO:0000428 ... P22139 11313499
    13019 1i6h:L (3.3) BS01 ZN 2.7.7.6 GO:0000428 ... P40422 11313499
    13020 1i6k:A (1.72) BS01 TYM 6.1.1.2 GO:0000166 ... P00953 11679724
    13021 1i6l:A (1.72) BS01 TYM 6.1.1.2 GO:0000166 ... P00953 11679724
    13022 1i6m:A (1.72) BS01 TYM 6.1.1.2 GO:0000166 ... P00953 11679724
    13023 1i6o:A (2.2) BS01 ZN 4.2.1.1 GO:0004089 ... P61517 11316870
    13024 1i6o:B (2.2) BS01 ZN 4.2.1.1 GO:0004089 ... P61517 11316870
    13025 1i6p:A (2.0) BS01 ZN 4.2.1.1 GO:0004089 ... P61517 11316870
    13026 1i6q:A (2.7) BS01 FE 3.4.21.- GO:0001503 ... Q9TUM0 11473113
    13027 1i6q:A (2.7) BS02 FE 3.4.21.- GO:0001503 ... Q9TUM0 11473113
    13028 1i6t:A (1.2) BS01 CA 3.6.1.1 GO:0000287 ... P0A7A9 11846572
    13029 1i6t:A (1.2) BS02 CA 3.6.1.1 GO:0000287 ... P0A7A9 11846572
    13030 1i6t:A (1.2) BS03 POP 3.6.1.1 GO:0000287 ... P0A7A9 11846572
    13031 1i6u:A (2.6) BS01 rna ? GO:0003735 ... P54041 11478863
    13032 1i6u:B (2.6) BS01 rna ? GO:0003735 ... P54041 11478863
    13033 1i6u:B (2.6) BS02 rna ? GO:0003735 ... P54041 11478863
    13034 1i6v:C (3.3) BS01 RFP 2.7.7.6 GO:0000428 ... Q9KWU7 11290327 PDBbind: -logKd/Ki=5.00, Ki=10uM
    13035 1i6x:A (2.2) BS01 CMP ? GO:0003677 ... P0ACJ8 N/A
    13036 1i6x:A (2.2) BS02 CMP ? GO:0003677 ... P0ACJ8 N/A
    13037 1i6x:B (2.2) BS01 CMP ? GO:0003677 ... P0ACJ8 N/A
    13038 1i73:A (1.4) BS01 peptide 3.4.24.34 GO:0004222 ... P22894 10978185
    13039 1i73:A (1.4) BS02 CA 3.4.24.34 GO:0004222 ... P22894 10978185
    13040 1i73:A (1.4) BS03 CA 3.4.24.34 GO:0004222 ... P22894 10978185
    13041 1i73:A (1.4) BS04 ZN 3.4.24.34 GO:0004222 ... P22894 10978185
    13042 1i73:A (1.4) BS05 ZN 3.4.24.34 GO:0004222 ... P22894 10978185
    13043 1i74:A (2.2) BS01 MN 3.6.1.1 GO:0004427 ... O68579 11525166
    13044 1i74:A (2.2) BS02 MN 3.6.1.1 GO:0004427 ... O68579 11525166
    13045 1i74:A (2.2) BS03 SO4 3.6.1.1 GO:0004427 ... O68579 11525166
    13046 1i74:A (2.2) BS04 SO4 3.6.1.1 GO:0004427 ... O68579 11525166
    13047 1i74:B (2.2) BS01 MN 3.6.1.1 GO:0004427 ... O68579 11525166
    13048 1i74:B (2.2) BS02 MN 3.6.1.1 GO:0004427 ... O68579 11525166
    13049 1i74:B (2.2) BS03 SO4 3.6.1.1 GO:0004427 ... O68579 11525166
    13050 1i75:A (2.0) BS01 CA 2.4.1.19 GO:0003824 ... P05618 11275559
    13051 1i75:A (2.0) BS02 CA 2.4.1.19 GO:0003824 ... P05618 11275559
    13052 1i75:A (2.0) BS03 NOJ 2.4.1.19 GO:0003824 ... P05618 11275559
    13053 1i75:A (2.0) BS04 NOJ 2.4.1.19 GO:0003824 ... P05618 11275559
    13054 1i75:B (2.0) BS01 CA 2.4.1.19 GO:0003824 ... P05618 11275559
    13055 1i75:B (2.0) BS02 CA 2.4.1.19 GO:0003824 ... P05618 11275559
    13056 1i75:B (2.0) BS03 NOJ 2.4.1.19 GO:0003824 ... P05618 11275559
    13057 1i75:B (2.0) BS04 NOJ 2.4.1.19 GO:0003824 ... P05618 11275559
    13058 1i76:A (1.2) BS01 CA 3.4.24.34 GO:0004222 ... P22894 10978185
    13059 1i76:A (1.2) BS02 CA 3.4.24.34 GO:0004222 ... P22894 10978185
    13060 1i76:A (1.2) BS03 ZN 3.4.24.34 GO:0004222 ... P22894 10978185
    13061 1i76:A (1.2) BS04 ZN 3.4.24.34 GO:0004222 ... P22894 10978185
    13062 1i76:A (1.2) BS05 BSI 3.4.24.34 GO:0004222 ... P22894 10978185
    13063 1i7d:A (2.05) BS01 dna 5.6.2.1 GO:0000287 ... P14294 11429611
    13064 1i7g:A (2.2) BS01 AZ2 ? GO:0003677 ... Q07869 11587644 MOAD: ic50=1uM
    PDBbind: -logKd/Ki=6.00, IC50=1.0uM
    BindingDB: EC50=820nM, Ki=1000nM
    13065 1i7g:A (2.2) BS02 CPQ ? GO:0003677 ... Q07869 11587644
    13066 1i7h:A (1.7) BS01 FES ? GO:0005515 ... P0A9R4 11551196
    13067 1i7h:B (1.7) BS01 FES ? GO:0005515 ... P0A9R4 11551196
    13068 1i7h:C (1.7) BS01 FES ? GO:0005515 ... P0A9R4 11551196
    13069 1i7i:A (2.35) BS01 AZ2 ? GO:0003677 ... P37231 11587644 PDBbind: -logKd/Ki=6.70, IC50=0.2uM
    BindingDB: EC50=704nM, Ki=18nM
    13070 1i7i:B (2.35) BS01 AZ2 ? GO:0003677 ... P37231 11587644 BindingDB: EC50=704nM, Ki=18nM
    13071 1i7l:A (2.35) BS01 ATP ? GO:0005524 ... Q63537 N/A
    13072 1i7l:B (2.35) BS01 ATP ? GO:0005524 ... Q63537 N/A
    13073 1i7q:B (1.95) BS01 GLU 4.1.3.27 GO:0000162 ... P00900 11371633
    13074 1i7q:D (1.95) BS01 GLU 4.1.3.27 GO:0000162 ... P00900 11371633
    13075 1i7y:A (2.5) BS01 CYC ? GO:0009579 ... Q9AM02 11601847
    13076 1i7y:B (2.5) BS01 CYC ? GO:0009579 ... Q71RW8 11601847
    13077 1i7y:B (2.5) BS02 CYC ? GO:0009579 ... Q71RW8 11601847
    13078 1i7z:A (2.3) BS01 COC ? GO:0002250 ... P01834 11469854 MOAD: Kd=0.4uM
    PDBbind: -logKd/Ki=6.40, Kd=0.4uM
    13079 1i7z:C (2.3) BS01 COC ? GO:0002250 ... P01834 11469854 MOAD: Kd=0.4uM
    13080 1i80:A (2.0) BS01 PO4 2.4.2.1 GO:0003824 ... P9WP01 11444966
    13081 1i80:A (2.0) BS02 9HX 2.4.2.1 GO:0003824 ... P9WP01 11444966 MOAD: Kd=0.39uM
    13082 1i80:A (2.0) BS03 IMR 2.4.2.1 GO:0003824 ... P9WP01 11444966
    13083 1i80:B (2.0) BS01 9HX 2.4.2.1 GO:0003824 ... P9WP01 11444966 MOAD: Kd=0.39uM
    PDBbind: -logKd/Ki=6.41, Kd=0.39uM
    13084 1i80:C (2.0) BS01 9HX 2.4.2.1 GO:0003824 ... P9WP01 11444966 MOAD: Kd=0.39uM
    PDBbind: -logKd/Ki=6.41, Kd=0.39uM
    13085 1i8i:A (2.4) BS01 peptide ? GO:0002250 ... P01660 11352579
    13086 1i8i:B (2.4) BS01 peptide ? GO:0002250 ... P18529 11352579
    13087 1i8j:A (1.9) BS01 ZN 4.2.1.24 GO:0000287 ... P0ACB2 11444968
    13088 1i8j:A (1.9) BS02 DSB 4.2.1.24 GO:0000287 ... P0ACB2 11444968 PDBbind: -logKd/Ki=4.41, IC50=39uM
    13089 1i8j:B (1.9) BS01 ZN 4.2.1.24 GO:0000287 ... P0ACB2 11444968
    13090 1i8j:B (1.9) BS02 DSB 4.2.1.24 GO:0000287 ... P0ACB2 11444968
    13091 1i8k:A (1.8) BS01 peptide ? GO:0002250 ... P01660 11352579
    13092 1i8k:B (1.8) BS01 peptide ? GO:0002250 ... P18529 11352579
    13093 1i8n:A (2.2) BS01 ROP ? GO:0005576 ... Q01747 11468390
    13094 1i8n:B (2.2) BS01 ROP ? GO:0005576 ... Q01747 11468390
    13095 1i8q:A (2.2) BS01 GC4 4.2.2.1 GO:0003824 ... Q53591 11527972
    13096 1i8q:A (2.2) BS02 GC4 4.2.2.1 GO:0003824 ... Q53591 11527972
    13097 1i8t:A (2.4) BS01 FAD 5.4.99.9 GO:0005515 ... P37747 11573090
    13098 1i8t:B (2.4) BS01 FAD 5.4.99.9 GO:0005515 ... P37747 11573090
    13099 1i8z:A (1.93) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 11831900
    13100 1i8z:A (1.93) BS02 INL 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 11831900 MOAD: ic50=1.27nM
    PDBbind: -logKd/Ki=8.90, IC50=1.27nM
    BindingDB: Ki=0.15nM, IC50=1.3nM
    13101 1i90:A (2.0) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 11831900
    13102 1i90:A (2.0) BS02 INM 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 11831900 MOAD: ic50=1.28nM
    PDBbind: -logKd/Ki=8.89, IC50=1.28nM
    13103 1i91:A (2.0) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 11831900
    13104 1i91:A (2.0) BS02 INQ 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 11831900 MOAD: ic50=1.15nM
    PDBbind: -logKd/Ki=8.94, IC50=1.15nM
    BindingDB: Ki=0.15nM, IC50=1.2nM
    13105 1i94:B (3.2) BS01 rna ? GO:0003735 ... P80371 11296217
    13106 1i94:B (3.2) BS02 WO2 ? GO:0003735 ... P80371 11296217
    13107 1i94:B (3.2) BS03 WO2 ? GO:0003735 ... P80371 11296217
    13108 1i94:C (3.2) BS01 rna ? GO:0003676 ... P80372 11296217
    13109 1i94:C (3.2) BS02 WO2 ? GO:0003676 ... P80372 11296217
    13110 1i94:D (3.2) BS01 rna ? GO:0003723 ... P80373 11296217
    13111 1i94:D (3.2) BS02 MG ? GO:0003723 ... P80373 11296217
    13112 1i94:D (3.2) BS03 MG ? GO:0003723 ... P80373 11296217
    13113 1i94:E (3.2) BS01 rna ? GO:0003723 ... Q5SHQ5 11296217
    13114 1i94:E (3.2) BS02 MG ? GO:0003723 ... Q5SHQ5 11296217
    13115 1i94:E (3.2) BS03 WO2 ? GO:0003723 ... Q5SHQ5 11296217
    13116 1i94:F (3.2) BS01 rna ? GO:0003735 ... Q5SLP8 11296217
    13117 1i94:G (3.2) BS01 rna ? GO:0000028 ... P17291 11296217
    13118 1i94:G (3.2) BS02 WO2 ? GO:0000028 ... P17291 11296217
    13119 1i94:H (3.2) BS01 rna ? GO:0003735 ... P0DOY9 11296217
    13120 1i94:H (3.2) BS02 WO2 ? GO:0003735 ... P0DOY9 11296217
    13121 1i94:I (3.2) BS01 rna ? GO:0000049 ... P80374 11296217
    13122 1i94:J (3.2) BS01 rna ? GO:0000049 ... Q5SHN7 11296217
    13123 1i94:J (3.2) BS02 WO2 ? GO:0000049 ... Q5SHN7 11296217
    13124 1i94:K (3.2) BS01 rna ? GO:0003735 ... P80376 11296217
    13125 1i94:K (3.2) BS02 WO2 ? GO:0003735 ... P80376 11296217
    13126 1i94:L (3.2) BS01 rna ? GO:0000049 ... Q5SHN3 11296217
    13127 1i94:L (3.2) BS02 MG ? GO:0000049 ... Q5SHN3 11296217
    13128 1i94:L (3.2) BS03 MG ? GO:0000049 ... Q5SHN3 11296217
    13129 1i94:L (3.2) BS04 MG ? GO:0000049 ... Q5SHN3 11296217
    13130 1i94:M (3.2) BS01 rna ? GO:0000049 ... P80377 11296217
    13131 1i94:N (3.2) BS01 rna ? GO:0003735 ... P0DOY6 11296217
    13132 1i94:N (3.2) BS02 ZN ? GO:0003735 ... P0DOY6 11296217
    13133 1i94:O (3.2) BS01 rna ? GO:0003735 ... Q5SJ76 11296217
    13134 1i94:P (3.2) BS01 rna ? GO:0003735 ... Q5SJH3 11296217
    13135 1i94:P (3.2) BS02 MG ? GO:0003735 ... Q5SJH3 11296217
    13136 1i94:Q (3.2) BS01 rna ? GO:0003735 ... P0DOY7 11296217
    13137 1i94:Q (3.2) BS02 MG ? GO:0003735 ... P0DOY7 11296217
    13138 1i94:Q (3.2) BS03 MG ? GO:0003735 ... P0DOY7 11296217
    13139 1i94:R (3.2) BS01 rna ? GO:0003735 ... Q5SLQ0 11296217
    13140 1i94:R (3.2) BS02 WO2 ? GO:0003735 ... Q5SLQ0 11296217
    13141 1i94:S (3.2) BS01 rna ? GO:0000028 ... Q5SHP2 11296217
    13142 1i94:T (3.2) BS01 rna ? GO:0003723 ... P80380 11296217
    13143 1i94:T (3.2) BS02 MG ? GO:0003723 ... P80380 11296217
    13144 1i94:T (3.2) BS03 MG ? GO:0003723 ... P80380 11296217
    13145 1i94:T (3.2) BS04 MG ? GO:0003723 ... P80380 11296217
    13146 1i95:C (4.5) BS01 rna ? GO:0003676 ... P80372 11296217
    13147 1i95:D (4.5) BS01 rna ? GO:0003723 ... P80373 11296217
    13148 1i95:G (4.5) BS01 WO2 ? GO:0000028 ... P17291 11296217
    13149 1i95:I (4.5) BS01 rna ? GO:0000049 ... P80374 11296217
    13150 1i95:J (4.5) BS01 rna ? GO:0000049 ... Q5SHN7 11296217
    13151 1i95:K (4.5) BS01 rna ? GO:0003735 ... P80376 11296217
    13152 1i95:K (4.5) BS02 WO2 ? GO:0003735 ... P80376 11296217
    13153 1i95:L (4.5) BS01 rna ? GO:0000049 ... Q5SHN3 11296217
    13154 1i95:N (4.5) BS01 rna ? GO:0003735 ... P0DOY6 11296217
    13155 1i95:P (4.5) BS01 rna ? GO:0003735 ... Q5SJH3 11296217
    13156 1i95:Q (4.5) BS01 rna ? GO:0003735 ... P0DOY7 11296217
    13157 1i95:S (4.5) BS01 rna ? GO:0000028 ... Q5SHP2 11296217
    13158 1i95:T (4.5) BS01 rna ? GO:0003723 ... P80380 11296217
    13159 1i96:B (4.2) BS01 rna ? GO:0003735 ... P80371 11296217
    13160 1i96:C (4.2) BS01 rna ? GO:0003676 ... P80372 11296217
    13161 1i96:D (4.2) BS01 rna ? GO:0003723 ... P80373 11296217
    13162 1i96:I (4.2) BS01 rna ? GO:0000049 ... P62669 11296217
    13163 1i96:J (4.2) BS01 rna ? GO:0000049 ... Q5SHN7 11296217
    13164 1i96:K (4.2) BS01 rna ? GO:0003735 ... P80376 11296217
    13165 1i96:K (4.2) BS02 WO2 ? GO:0003735 ... P80376 11296217
    13166 1i96:L (4.2) BS01 rna ? GO:0000049 ... Q5SHN3 11296217
    13167 1i96:P (4.2) BS01 rna ? GO:0003735 ... Q5SJH3 11296217
    13168 1i96:Q (4.2) BS01 rna ? GO:0003735 ... P0DOY7 11296217
    13169 1i96:S (4.2) BS01 rna ? GO:0000028 ... Q5SHP2 11296217
    13170 1i96:T (4.2) BS01 rna ? GO:0003723 ... P80380 11296217
    13171 1i97:C (4.5) BS01 rna ? GO:0003676 ... P80372 11296217
    13172 1i97:D (4.5) BS01 rna ? GO:0003723 ... P80373 11296217
    13173 1i97:D (4.5) BS02 TAC ? GO:0003723 ... P80373 11296217
    13174 1i97:E (4.5) BS01 rna ? GO:0003723 ... Q5SHQ5 11296217
    13175 1i97:H (4.5) BS01 rna ? GO:0003735 ... P0DOY9 11296217
    13176 1i97:I (4.5) BS01 rna ? GO:0000049 ... P80374 11296217
    13177 1i97:I (4.5) BS02 TAC ? GO:0000049 ... P80374 11296217
    13178 1i97:J (4.5) BS01 rna ? GO:0000049 ... Q5SHN7 11296217
    13179 1i97:K (4.5) BS01 rna ? GO:0003735 ... P80376 11296217
    13180 1i97:K (4.5) BS02 WO2 ? GO:0003735 ... P80376 11296217
    13181 1i97:L (4.5) BS01 rna ? GO:0000049 ... Q5SHN3 11296217
    13182 1i97:M (4.5) BS01 rna ? GO:0000049 ... P80377 11296217
    13183 1i97:N (4.5) BS01 rna ? GO:0003735 ... P0DOY6 11296217
    13184 1i97:O (4.5) BS01 rna ? GO:0003735 ... Q5SJ76 11296217
    13185 1i97:P (4.5) BS01 rna ? GO:0003735 ... Q5SJH3 11296217
    13186 1i97:Q (4.5) BS01 rna ? GO:0003735 ... P0DOY7 11296217
    13187 1i97:R (4.5) BS01 WO2 ? GO:0003735 ... Q5SLQ0 11296217
    13188 1i97:T (4.5) BS01 rna ? GO:0003723 ... P80380 11296217
    13189 1i9a:A (2.5) BS01 MN 5.3.3.2 GO:0000287 ... Q46822 11698677
    13190 1i9a:B (2.5) BS01 MN 5.3.3.2 GO:0000287 ... Q46822 11698677
    13191 1i9b:A (2.7) BS01 CA ? GO:0004888 ... P58154 11357122
    13192 1i9b:A (2.7) BS02 CA ? GO:0004888 ... P58154 11357122
    13193 1i9b:B (2.7) BS01 CA ? GO:0004888 ... P58154 11357122
    13194 1i9b:C (2.7) BS01 CA ? GO:0004888 ... P58154 11357122
    13195 1i9b:D (2.7) BS01 CA ? GO:0004888 ... P58154 11357122
    13196 1i9b:E (2.7) BS01 CA ? GO:0004888 ... P58154 11357122
    13197 1i9b:E (2.7) BS02 CA ? GO:0004888 ... P58154 11357122
    13198 1i9g:A (1.98) BS01 SAM 2.1.1.220 GO:0005886 ... P9WFZ1 11554794
    13199 1i9l:A (1.93) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 11572683
    13200 1i9l:A (1.93) BS02 INV 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 11572683 MOAD: Kd=3.3nM
    PDBbind: -logKd/Ki=8.48, Kd=3.3nM

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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