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BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    39001 1x8g:A (1.7) BS02 CO3 3.5.2.6 GO:0008270 ... P26918 15588826
    39002 1x8h:A (1.6) BS01 ZN 3.5.2.6 GO:0008270 ... P26918 15588826
    39003 1x8h:A (1.6) BS02 CO3 3.5.2.6 GO:0008270 ... P26918 15588826
    39004 1x8i:A (1.9) BS01 ZN 3.5.2.6 GO:0008270 ... P26918 15588826
    39005 1x8i:A (1.9) BS02 BMH 3.5.2.6 GO:0008270 ... P26918 15588826
    39006 1x8j:A (2.35) BS01 CA ? GO:0005737 ... Q26490 15608121
    39007 1x8j:A (2.35) BS02 A3P ? GO:0005737 ... Q26490 15608121
    39008 1x8j:A (2.35) BS03 AOI ? GO:0005737 ... Q26490 15608121 MOAD: Ki=0.11uM
    PDBbind: -logKd/Ki=6.96, Ki=0.11uM
    39009 1x8j:B (2.35) BS01 A3P ? GO:0005737 ... Q26490 15608121
    39010 1x8j:B (2.35) BS02 CA ? GO:0005737 ... Q26490 15608121
    39011 1x8j:B (2.35) BS03 AOI ? GO:0005737 ... Q26490 15608121 MOAD: Ki=0.11uM
    39012 1x8k:A (2.75) BS01 CA ? GO:0005737 ... Q26490 15608121
    39013 1x8k:A (2.75) BS02 ANR ? GO:0005737 ... Q26490 15608121
    39014 1x8k:A (2.75) BS03 A3P ? GO:0005737 ... Q26490 15608121
    39015 1x8k:B (2.75) BS01 CA ? GO:0005737 ... Q26490 15608121
    39016 1x8k:B (2.75) BS02 A3P ? GO:0005737 ... Q26490 15608121
    39017 1x8k:B (2.75) BS03 ANR ? GO:0005737 ... Q26490 15608121
    39018 1x8l:A (2.1) BS01 CA ? GO:0005737 ... Q26490 15608121
    39019 1x8l:A (2.1) BS02 OXR ? GO:0005737 ... Q26490 15608121
    39020 1x8l:A (2.1) BS03 A3P ? GO:0005737 ... Q26490 15608121
    39021 1x8l:B (2.1) BS01 CA ? GO:0005737 ... Q26490 15608121
    39022 1x8l:B (2.1) BS02 A3P ? GO:0005737 ... Q26490 15608121
    39023 1x8l:B (2.1) BS03 OXR ? GO:0005737 ... Q26490 15608121
    39024 1x8n:A (1.08) BS01 HEM 1.7.6.1 GO:0005576 ... Q94734 15504026
    39025 1x8o:A (1.01) BS01 HEM 1.7.6.1 GO:0005576 ... Q94734 15504026
    39026 1x8o:A (1.01) BS02 NO 1.7.6.1 GO:0005576 ... Q94734 15504026
    39027 1x8p:A (0.85) BS01 HEM 1.7.6.1 GO:0005576 ... Q94734 15504026
    39028 1x8q:A (0.85) BS01 HEM 1.7.6.1 GO:0005576 ... Q94734 15504026
    39029 1x8r:A (1.5) BS01 SC1 2.5.1.19 GO:0003824 ... P0A6D3 15736934 MOAD: Ki=2.9uM
    PDBbind: -logKd/Ki=6.12, Ki=750nM
    BindingDB: Kd=15nM, Ki=15nM
    39030 1x8t:A (1.9) BS01 RC1 2.5.1.19 GO:0003824 ... P0A6D3 15736934 MOAD: Ki=16nM
    PDBbind: -logKd/Ki=7.80, Ki=16nM
    39031 1x8u:A (2.2) BS01 CM2 ? GO:0005506 ... P80188 15642259
    39032 1x8u:B (2.2) BS01 CM2 ? GO:0005506 ... P80188 15642259
    39033 1x8u:C (2.2) BS01 CM2 ? GO:0005506 ... P80188 15642259
    39034 1x8v:A (1.55) BS01 HEM 1.14.15.36 GO:0004497 ... P9WPP9 15530358
    39035 1x8v:A (1.55) BS02 ESL 1.14.15.36 GO:0004497 ... P9WPP9 15530358 MOAD: Kd=100uM
    39036 1x8v:A (1.55) BS03 ESL 1.14.15.36 GO:0004497 ... P9WPP9 15530358 MOAD: Kd=100uM
    39037 1x92:A (2.3) BS01 M7P 5.3.1.28 GO:0005737 ... Q9HVZ0 18056714
    39038 1x92:B (2.3) BS01 M7P 5.3.1.28 GO:0005737 ... Q9HVZ0 18056714
    39039 1x96:A (1.4) BS01 NAP 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54
    GO:0001523 ... P15121 15317464
    39040 1x97:A (1.4) BS01 NAP 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54
    GO:0001523 ... P15121 15317464
    39041 1x97:A (1.4) BS02 FIR 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54
    GO:0001523 ... P15121 15317464 MOAD: ic50=0.57uM
    BindingDB: IC50=570nM
    39042 1x98:A (1.3) BS01 NAP 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54
    GO:0001523 ... P15121 15317464
    39043 1x9d:A (1.41) BS01 Z5L 3.2.1.113 GO:0004571 ... Q9UKM7 15713668
    39044 1x9d:A (1.41) BS02 MAN 3.2.1.113 GO:0004571 ... Q9UKM7 15713668
    39045 1x9f:A (2.6) BS01 HEM ? GO:0005344 ... P13579 15504406
    39046 1x9f:A (2.6) BS02 HEM ? GO:0005344 ... P13579 15504406
    39047 1x9f:B (2.6) BS01 HEM ? GO:0001666 ... P02218 15504406
    39048 1x9f:C (2.6) BS01 HEM ? GO:0005344 ... P11069 15504406
    39049 1x9f:C (2.6) BS02 HEM ? GO:0005344 ... P11069 15504406
    39050 1x9f:D (2.6) BS01 HEM ? GO:0005344 ... O61233 15504406
    39051 1x9f:E (2.6) BS01 HEM ? GO:0005344 ... P13579 15504406
    39052 1x9f:E (2.6) BS02 HEM ? GO:0005344 ... P13579 15504406
    39053 1x9f:F (2.6) BS01 HEM ? GO:0001666 ... P02218 15504406
    39054 1x9f:G (2.6) BS01 HEM ? GO:0005344 ... P11069 15504406
    39055 1x9f:H (2.6) BS01 HEM ? GO:0005344 ... O61233 15504406
    39056 1x9f:H (2.6) BS02 HEM ? GO:0005344 ... O61233 15504406
    39057 1x9f:I (2.6) BS01 HEM ? GO:0005344 ... P13579 15504406
    39058 1x9f:I (2.6) BS02 HEM ? GO:0005344 ... P13579 15504406
    39059 1x9f:J (2.6) BS01 HEM ? GO:0001666 ... P02218 15504406
    39060 1x9f:K (2.6) BS01 HEM ? GO:0005344 ... P11069 15504406
    39061 1x9f:L (2.6) BS01 HEM ? GO:0005344 ... O61233 15504406
    39062 1x9p:A (3.3) BS01 C15 ? GO:0005198 ... P03276 15629723
    39063 1x9p:A (3.3) BS02 C15 ? GO:0005198 ... P03276 15629723
    39064 1x9t:A (3.5) BS01 peptide ? GO:0005198 ... P03276 15629723
    39065 1x9t:A (3.5) BS02 C15 ? GO:0005198 ... P03276 15629723
    39066 1x9t:A (3.5) BS03 C15 ? GO:0005198 ... P03276 15629723
    39067 1xa4:B (1.9) BS01 COA 2.8.3.21 GO:0003824 ... P31572 15518548
    39068 1xa5:A (2.12) BS01 CA ? GO:0000922 ... P62157 15596444
    39069 1xa5:A (2.12) BS02 CA ? GO:0000922 ... P62157 15596444
    39070 1xa5:A (2.12) BS03 CA ? GO:0000922 ... P62157 15596444
    39071 1xa5:A (2.12) BS04 CA ? GO:0000922 ... P62157 15596444
    39072 1xa5:A (2.12) BS05 KAR ? GO:0000922 ... P62157 15596444 MOAD: Kd=316nM
    PDBbind: -logKd/Ki=6.50, Kd=316nM
    39073 1xa6:A (3.2) BS01 ZN ? GO:0005096 ... P52757 15507211
    39074 1xa6:A (3.2) BS02 ZN ? GO:0005096 ... P52757 15507211
    39075 1xag:A (2.45) BS01 ZN 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39076 1xag:A (2.45) BS02 NAD 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39077 1xag:A (2.45) BS03 CRB 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39078 1xah:A (2.2) BS01 ZN 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39079 1xah:A (2.2) BS02 NAD 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39080 1xah:B (2.2) BS01 ZN 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39081 1xah:B (2.2) BS02 NAD 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39082 1xai:A (2.3) BS01 ZN 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39083 1xai:A (2.3) BS02 CRB 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39084 1xai:B (2.3) BS01 ZN 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39085 1xai:B (2.3) BS02 CRB 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39086 1xaj:A (2.35) BS01 ZN 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39087 1xaj:A (2.35) BS02 NAD 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39088 1xaj:A (2.35) BS03 CRB 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39089 1xaj:B (2.35) BS01 ZN 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39090 1xaj:B (2.35) BS02 NAD 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39091 1xaj:B (2.35) BS03 CRB 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39092 1xal:A (2.8) BS01 ZN 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39093 1xal:A (2.8) BS02 NAD 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39094 1xal:A (2.8) BS03 CRB 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39095 1xal:B (2.8) BS01 ZN 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39096 1xal:B (2.8) BS02 NAD 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39097 1xal:B (2.8) BS03 CRB 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    39098 1xap:A (2.1) BS01 TTB ? GO:0003677 ... P10826 15319780 MOAD: Kd=2.5nM
    PDBbind: -logKd/Ki=8.70, Kd=2nM
    BindingDB: EC50=4nM, Ki=0.500000nM, Kd=5nM, IC50=5nM
    39099 1xb3:A (1.501) BS01 CU ? GO:0005507 ... P00282 15449946
    39100 1xb3:B (1.501) BS01 CU ? GO:0005507 ... P00282 15449946
    39101 1xb6:A (1.823) BS01 CU ? GO:0005507 ... P00282 15449946
    39102 1xb6:B (1.823) BS01 CU ? GO:0005507 ... P00282 15449946
    39103 1xb8:A (2.0) BS01 ZN ? GO:0005507 ... P00282 15449946
    39104 1xb8:C (2.0) BS01 ZN ? GO:0005507 ... P00282 15449946
    39105 1xbp:A (3.5) BS01 rna ? GO:0002181 ... Q9RXJ9 15554968
    39106 1xbp:B (3.5) BS01 rna ? GO:0003735 ... Q9RXK2 15554968
    39107 1xbp:C (3.5) BS01 rna ? GO:0003735 ... Q9RXK1 15554968
    39108 1xbp:G (3.5) BS01 rna ? GO:0003735 ... Q9RSS7 15554968
    39109 1xbp:H (3.5) BS01 rna ? GO:0003729 ... Q9RXY1 15554968
    39110 1xbp:I (3.5) BS01 rna ? GO:0003735 ... Q9RXJ2 15554968
    39111 1xbp:J (3.5) BS01 rna ? GO:0003735 ... Q9RSK9 15554968
    39112 1xbp:L (3.5) BS01 rna ? GO:0003735 ... Q9RSJ5 15554968
    39113 1xbp:O (3.5) BS01 rna ? GO:0000027 ... Q9RSW7 15554968
    39114 1xbp:P (3.5) BS01 rna ? GO:0003723 ... Q9RY64 15554968
    39115 1xbp:Q (3.5) BS01 rna ? GO:0003735 ... Q9RXJ7 15554968
    39116 1xbp:R (3.5) BS01 rna ? GO:0000027 ... Q9RXK0 15554968
    39117 1xbp:T (3.5) BS01 rna ? GO:0000049 ... Q9RX88 15554968
    39118 1xbp:X (3.5) BS01 rna ? GO:0003735 ... Q9RSL0 15554968
    39119 1xbp:Y (3.5) BS01 rna ? GO:0000049 ... Q9RW44 15554968
    39120 1xbp:Z (3.5) BS01 rna ? GO:0003735 ... P49228 15554968
    39121 1xbr:A (2.5) BS01 dna ? GO:0000978 ... P24781 9349824
    39122 1xbr:A (2.5) BS02 dna ? GO:0000978 ... P24781 9349824
    39123 1xbr:B (2.5) BS01 dna ? GO:0000978 ... P24781 9349824
    39124 1xbr:B (2.5) BS02 dna ? GO:0000978 ... P24781 9349824
    39125 1xc4:A (2.8) BS01 SO4 4.2.1.20 GO:0000162 ... P0A877 15451433
    39126 1xc4:A (2.8) BS02 GOL 4.2.1.20 GO:0000162 ... P0A877 15451433
    39127 1xc4:B (2.8) BS01 SO4 4.2.1.20 GO:0000162 ... P0A877 15451433
    39128 1xc4:B (2.8) BS02 GOL 4.2.1.20 GO:0000162 ... P0A877 15451433
    39129 1xc6:A (2.1) BS01 MAN 3.2.1.23 GO:0000272 ... Q700S9 15491613
    39130 1xc6:A (2.1) BS02 MAN 3.2.1.23 GO:0000272 ... Q700S9 15491613
    39131 1xc6:A (2.1) BS03 MAN 3.2.1.23 GO:0000272 ... Q700S9 15491613
    39132 1xc6:A (2.1) BS04 GAL 3.2.1.23 GO:0000272 ... Q700S9 15491613
    39133 1xc7:A (1.83) BS01 GL6 2.4.1.1 GO:0000166 ... P00489 15653344 MOAD: Ki=5.1mM
    BindingDB: Ki=5900000nM
    39134 1xc7:A (1.83) BS02 PLP 2.4.1.1 GO:0000166 ... P00489 15653344
    39135 1xcb:A (2.9) BS01 NAD ? GO:0003677 ... Q9X2V5 15642260
    39136 1xcb:A (2.9) BS02 NAD ? GO:0003677 ... Q9X2V5 15642260
    39137 1xcb:B (2.9) BS01 NAD ? GO:0003677 ... Q9X2V5 15642260
    39138 1xcb:B (2.9) BS02 NAD ? GO:0003677 ... Q9X2V5 15642260
    39139 1xcb:C (2.9) BS01 NAD ? GO:0003677 ... Q9X2V5 15642260
    39140 1xcb:C (2.9) BS02 NAD ? GO:0003677 ... Q9X2V5 15642260
    39141 1xcb:D (2.9) BS01 NAD ? GO:0003677 ... Q9X2V5 15642260
    39142 1xcb:D (2.9) BS02 CA ? GO:0003677 ... Q9X2V5 15642260
    39143 1xcb:D (2.9) BS03 NAD ? GO:0003677 ... Q9X2V5 15642260
    39144 1xcb:E (2.9) BS01 NAD ? GO:0003677 ... Q9X2V5 15642260
    39145 1xcb:F (2.9) BS01 NAD ? GO:0003677 ... Q9X2V5 15642260
    39146 1xcb:F (2.9) BS02 NAD ? GO:0003677 ... Q9X2V5 15642260
    39147 1xcb:G (2.9) BS01 NAD ? GO:0003677 ... Q9X2V5 15642260
    39148 1xch:A (1.7) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P68082 9300804
    39149 1xcj:A (2.0) BS01 SAH 2.1.1.2 GO:0005634 ... P10868 15533043
    39150 1xcj:A (2.0) BS02 NMG 2.1.1.2 GO:0005634 ... P10868 15533043
    39151 1xcl:A (2.0) BS01 SAH 2.1.1.2 GO:0005634 ... P10868 15533043
    39152 1xcl:A (2.0) BS02 GAI 2.1.1.2 GO:0005634 ... P10868 15533043
    39153 1xcm:A (1.84) BS01 GNP 3.6.5.2 GO:0003924 ... P01112 N/A
    39154 1xco:A (2.85) BS01 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39155 1xco:A (2.85) BS02 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39156 1xco:A (2.85) BS03 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39157 1xco:A (2.85) BS04 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39158 1xco:B (2.85) BS01 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39159 1xco:B (2.85) BS02 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39160 1xco:B (2.85) BS03 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39161 1xco:B (2.85) BS04 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39162 1xco:B (2.85) BS05 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39163 1xco:C (2.85) BS01 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39164 1xco:C (2.85) BS02 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39165 1xco:C (2.85) BS03 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39166 1xco:C (2.85) BS04 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39167 1xco:D (2.85) BS01 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39168 1xco:D (2.85) BS02 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39169 1xco:D (2.85) BS03 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39170 1xco:D (2.85) BS04 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39171 1xco:E (2.85) BS01 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39172 1xco:E (2.85) BS02 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39173 1xco:E (2.85) BS03 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39174 1xco:F (2.85) BS01 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39175 1xco:F (2.85) BS02 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39176 1xco:F (2.85) BS03 UVW 2.3.1.8 GO:0005737 ... P39646 16283428
    39177 1xcr:A (1.7) BS01 ZN 3.1.-.- GO:0005515 ... Q9H0W9 16522806
    39178 1xcr:B (1.7) BS01 ZN 3.1.-.- GO:0005515 ... Q9H0W9 16522806
    39179 1xcw:A (2.0) BS01 GLC 3.2.1.1 GO:0003824 ... P04746 15736945
    39180 1xcw:A (2.0) BS02 AC1 3.2.1.1 GO:0003824 ... P04746 15736945
    39181 1xcw:A (2.0) BS03 CA 3.2.1.1 GO:0003824 ... P04746 15736945
    39182 1xcx:A (1.9) BS01 GLC 3.2.1.1 GO:0003824 ... P04746 15736945
    39183 1xcx:A (1.9) BS02 AC1 3.2.1.1 GO:0003824 ... P04746 15736945
    39184 1xcx:A (1.9) BS03 CA 3.2.1.1 GO:0003824 ... P04746 15736945
    39185 1xd0:A (2.0) BS01 ARE 3.2.1.1 GO:0003824 ... P04746 15736945 MOAD: Ki=0.075uM
    PDBbind: -logKd/Ki=7.12, Ki=0.075uM
    39186 1xd0:A (2.0) BS02 CA 3.2.1.1 GO:0003824 ... P04746 15736945
    39187 1xd1:A (2.2) BS01 6SA 3.2.1.1 GO:0003824 ... P04746 15736945 MOAD: Ki=0.012uM
    BindingDB: Ki=12nM
    39188 1xd1:A (2.2) BS02 CA 3.2.1.1 GO:0003824 ... P04746 15736945
    39189 1xd2:A (2.7) BS01 MG 3.6.5.2 GO:0003924 ... P01112 15507210
    39190 1xd2:A (2.7) BS02 GDP 3.6.5.2 GO:0003924 ... P01112 15507210
    39191 1xd3:A (1.45) BS01 MG 3.4.19.12 GO:0004843 ... P15374 15531586
    39192 1xd3:A (1.45) BS02 MG 3.4.19.12 GO:0004843 ... P15374 15531586
    39193 1xd3:A (1.45) BS03 GVE 3.4.19.12 GO:0004843 ... P15374 15531586
    39194 1xd3:C (1.45) BS01 MG 3.4.19.12 GO:0004843 ... P15374 15531586
    39195 1xd3:C (1.45) BS02 MG 3.4.19.12 GO:0004843 ... P15374 15531586
    39196 1xd3:C (1.45) BS03 GVE 3.4.19.12 GO:0004843 ... P15374 15531586
    39197 1xdk:A (2.9) BS01 peptide ? GO:0003677 ... P28700 15528208
    39198 1xdk:A (2.9) BS02 9CR ? GO:0003677 ... P28700 15528208 BindingDB: IC50=82nM, Kd=32nM, EC50=200nM
    39199 1xdk:B (2.9) BS01 peptide ? GO:0003677 ... P22605 15528208
    39200 1xdk:B (2.9) BS02 9CR ? GO:0003677 ... P22605 15528208 BindingDB: Kd=7nM

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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