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BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    33401 1tsr:B (2.2) BS02 dna ? GO:0000976 ... P04637 8023157
    33402 1tsr:B (2.2) BS03 ZN ? GO:0000976 ... P04637 8023157
    33403 1tsr:C (2.2) BS01 dna ? GO:0000976 ... P04637 8023157
    33404 1tsr:C (2.2) BS02 ZN ? GO:0000976 ... P04637 8023157
    33405 1tsv:A (2.9) BS01 UMP 2.1.1.45 GO:0004799 ... P00469 9053905 PDBbind: -logKd/Ki=4.80, Kd=16.0uM
    33406 1tsx:A (2.5) BS01 UMP 2.1.1.45 GO:0004799 ... P00469 9053905
    33407 1tsy:A (2.2) BS01 UMP 2.1.1.45 GO:0004799 ... P00469 9053905 MOAD: Kd=11uM
    PDBbind: -logKd/Ki=4.96, Kd=11.0uM
    33408 1tsz:A (2.75) BS01 PO4 2.1.1.45 GO:0004799 ... P00469 9053905
    33409 1tt0:A (1.8) BS01 ACT 1.1.3.10 GO:0000166 ... Q7ZA32 15288786
    33410 1tt0:A (1.8) BS02 FAD 1.1.3.10 GO:0000166 ... Q7ZA32 15288786
    33411 1tt0:B (1.8) BS01 ACT 1.1.3.10 GO:0000166 ... Q7ZA32 15288786
    33412 1tt0:B (1.8) BS02 FAD 1.1.3.10 GO:0000166 ... Q7ZA32 15288786
    33413 1tt0:C (1.8) BS01 ACT 1.1.3.10 GO:0000166 ... Q7ZA32 15288786
    33414 1tt0:C (1.8) BS02 FAD 1.1.3.10 GO:0000166 ... Q7ZA32 15288786
    33415 1tt0:D (1.8) BS01 ACT 1.1.3.10 GO:0000166 ... Q7ZA32 15288786
    33416 1tt0:D (1.8) BS02 FAD 1.1.3.10 GO:0000166 ... Q7ZA32 15288786
    33417 1tt1:A (1.93) BS01 KAI ? GO:0015276 ... P42260 15721240 MOAD: Ki=64.6nM
    PDBbind: -logKd/Ki=8.15, IC50=0.007uM
    BindingDB: Ki=12.7nM, Kd=39nM, EC50=1800nM
    33418 1tt1:B (1.93) BS01 KAI ? GO:0015276 ... P42260 15721240 MOAD: Ki=64.6nM
    BindingDB: Ki=12.7nM, Kd=39nM, EC50=1800nM
    33419 1tt5:B (2.6) BS01 peptide 6.2.1.64 GO:0000278 ... Q8TBC4 15361859
    33420 1tt5:B (2.6) BS02 ZN 6.2.1.64 GO:0000278 ... Q8TBC4 15361859
    33421 1tt5:D (2.6) BS01 peptide 6.2.1.64 GO:0000278 ... Q8TBC4 15361859
    33422 1tt5:D (2.6) BS02 ZN 6.2.1.64 GO:0000278 ... Q8TBC4 15361859
    33423 1tt6:A (1.8) BS01 DES ? GO:0005179 ... P02766 15469931
    33424 1tt6:B (1.8) BS01 DES ? GO:0005179 ... P02766 15469931
    33425 1tth:A (2.8) BS01 PAL 2.1.3.2 GO:0004070 ... P0A786 15288791
    33426 1tth:B (2.8) BS01 ZN ? GO:0005515 ... P0A7F3 15288791
    33427 1tth:C (2.8) BS01 PAL 2.1.3.2 GO:0004070 ... P0A786 15288791
    33428 1tth:D (2.8) BS01 ZN ? GO:0005515 ... P0A7F3 15288791
    33429 1tti:A (2.4) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 8591044
    33430 1ttj:A (2.4) BS01 PGH 5.3.1.1 GO:0004807 ... P04789 8591044
    33431 1ttm:A (1.95) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 15453828
    33432 1ttm:A (1.95) BS02 667 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 15453828 MOAD: Kd=45nM
    PDBbind: -logKd/Ki=7.35, Kd=45nM
    BindingDB: IC50=25nM, Ki=21nM, Kd=45nM
    33433 1ttp:B (2.3) BS01 PLP 4.2.1.20 GO:0000162 ... P0A2K1 8672457
    33434 1ttq:B (2.0) BS01 PLP 4.2.1.20 GO:0000162 ... P0A2K1 8672457
    33435 1ttt:A (2.7) BS01 rna ? GO:0003746 ... Q01698 7491491
    33436 1ttt:A (2.7) BS02 rna ? GO:0003746 ... Q01698 7491491
    33437 1ttt:A (2.7) BS03 PHE ? GO:0003746 ... Q01698 7491491
    33438 1ttt:A (2.7) BS04 MG ? GO:0003746 ... Q01698 7491491
    33439 1ttt:A (2.7) BS05 GNP ? GO:0003746 ... Q01698 7491491
    33440 1ttt:B (2.7) BS01 rna ? GO:0003746 ... Q01698 7491491
    33441 1ttt:B (2.7) BS02 rna ? GO:0003746 ... Q01698 7491491
    33442 1ttt:B (2.7) BS03 PHE ? GO:0003746 ... Q01698 7491491
    33443 1ttt:B (2.7) BS04 MG ? GO:0003746 ... Q01698 7491491
    33444 1ttt:B (2.7) BS05 GNP ? GO:0003746 ... Q01698 7491491
    33445 1ttt:C (2.7) BS01 rna ? GO:0003746 ... Q01698 7491491
    33446 1ttt:C (2.7) BS02 rna ? GO:0003746 ... Q01698 7491491
    33447 1ttt:C (2.7) BS03 PHE ? GO:0003746 ... Q01698 7491491
    33448 1ttt:C (2.7) BS04 MG ? GO:0003746 ... Q01698 7491491
    33449 1ttt:C (2.7) BS05 GNP ? GO:0003746 ... Q01698 7491491
    33450 1ttu:A (2.85) BS01 dna ? GO:0000978 ... V6CLJ5 15297877
    33451 1ttu:A (2.85) BS02 dna ? GO:0000978 ... V6CLJ5 15297877
    33452 1ttv:A (-1.00) BS01 IMY 2.3.2.27 GO:0005634 ... P56273 15557803 PDBbind: -logKd/Ki=6.80, IC50=160nM
    33453 1ttx:A (-1.00) BS01 CA ? GO:0005509 ... P0CE72 15610002
    33454 1ttx:A (-1.00) BS02 CA ? GO:0005509 ... P0CE72 15610002
    33455 1tu0:A (2.55) BS01 PCT 2.1.3.2 GO:0004070 ... P0A786 15288791
    33456 1tu0:B (2.55) BS01 ZN ? GO:0005515 ... P0A7F3 15288791
    33457 1tu0:C (2.55) BS01 PCT 2.1.3.2 GO:0004070 ... P0A786 15288791
    33458 1tu0:D (2.55) BS01 ZN ? GO:0005515 ... P0A7F3 15288791
    33459 1tu2:A (-1.00) BS01 CU ? GO:0005507 ... P46444 15705583
    33460 1tu2:B (-1.00) BS01 HEC ? GO:0005506 ... Q93SW9 15705583
    33461 1tu5:A (2.37) BS01 CU 1.4.3.21 GO:0005507 ... Q29437 15701511
    33462 1tu5:A (2.37) BS02 CA 1.4.3.21 GO:0005507 ... Q29437 15701511
    33463 1tu5:A (2.37) BS03 CA 1.4.3.21 GO:0005507 ... Q29437 15701511
    33464 1tu5:B (2.37) BS01 CU 1.4.3.21 GO:0005507 ... Q29437 15701511
    33465 1tu5:B (2.37) BS02 CA 1.4.3.21 GO:0005507 ... Q29437 15701511
    33466 1tu5:B (2.37) BS03 CA 1.4.3.21 GO:0005507 ... Q29437 15701511
    33467 1tu7:A (1.5) BS01 GSH 2.5.1.18 GO:0004364 ... P46427 15640152
    33468 1tu7:B (1.5) BS01 GSH 2.5.1.18 GO:0004364 ... P46427 15640152
    33469 1tu8:A (1.8) BS01 GTX 2.5.1.18 GO:0004364 ... P46427 15640152
    33470 1tu8:B (1.8) BS01 GTX 2.5.1.18 GO:0004364 ... P46427 15640152
    33471 1tu8:C (1.8) BS01 GTX 2.5.1.18 GO:0004364 ... P46427 15640152
    33472 1tu8:D (1.8) BS01 GTX 2.5.1.18 GO:0004364 ... P46427 15640152
    33473 1tub:A (3.7) BS01 GTP 3.6.5.- GO:0000226 ... P02550 9428769
    33474 1tub:B (3.7) BS01 GTP ? GO:0000226 ... P02554 9428769
    33475 1tub:B (3.7) BS02 GDP ? GO:0000226 ... P02554 9428769
    33476 1tub:B (3.7) BS03 TXL ? GO:0000226 ... P02554 9428769
    33477 1tug:A (2.1) BS01 MLI 2.1.3.2 GO:0004070 ... P0A786 15288791
    33478 1tug:A (2.1) BS02 PCT 2.1.3.2 GO:0004070 ... P0A786 15288791
    33479 1tug:B (2.1) BS01 ZN ? GO:0005515 ... P0A7F3 15288791
    33480 1tug:B (2.1) BS02 CTP ? GO:0005515 ... P0A7F3 15288791
    33481 1tug:C (2.1) BS01 PCT 2.1.3.2 GO:0004070 ... P0A786 15288791
    33482 1tug:D (2.1) BS01 ZN ? GO:0005515 ... P0A7F3 15288791
    33483 1tug:D (2.1) BS02 CTP ? GO:0005515 ... P0A7F3 15288791
    33484 1tui:A (2.7) BS01 MG ? GO:0003746 ... Q01698 8939739
    33485 1tui:A (2.7) BS02 GDP ? GO:0003746 ... Q01698 8939739
    33486 1tui:B (2.7) BS01 GDP ? GO:0003746 ... Q01698 8939739
    33487 1tui:C (2.7) BS01 GDP ? GO:0003746 ... Q01698 8939739
    33488 1tuk:A (1.12) BS01 PGM ? GO:0005576 ... P82900 15805594
    33489 1tup:A (2.2) BS01 dna ? GO:0000976 ... P04637 8023157
    33490 1tup:A (2.2) BS02 ZN ? GO:0000976 ... P04637 8023157
    33491 1tup:B (2.2) BS01 dna ? GO:0000976 ... P04637 8023157
    33492 1tup:B (2.2) BS02 dna ? GO:0000976 ... P04637 8023157
    33493 1tup:B (2.2) BS03 ZN ? GO:0000976 ... P04637 8023157
    33494 1tup:C (2.2) BS01 dna ? GO:0000976 ... P04637 8023157
    33495 1tup:C (2.2) BS02 ZN ? GO:0000976 ... P04637 8023157
    33496 1tuu:A (2.5) BS01 SO4 2.7.2.1 GO:0000287 ... P38502 15647264
    33497 1tuu:A (2.5) BS02 ADP 2.7.2.1 GO:0000287 ... P38502 15647264
    33498 1tuu:B (2.5) BS01 AMP 2.7.2.1 GO:0000287 ... P38502 15647264
    33499 1tuu:B (2.5) BS02 PIS 2.7.2.1 GO:0000287 ... P38502 15647264
    33500 1tuv:A (1.7) BS01 VK3 1.-.-.- GO:0005829 ... P0ADU2 15613473
    33501 1tuy:A (3.0) BS01 SO4 2.7.2.1 GO:0000287 ... P38502 15647264
    33502 1tuy:A (3.0) BS02 ADP 2.7.2.1 GO:0000287 ... P38502 15647264
    33503 1tuy:B (3.0) BS01 ADP 2.7.2.1 GO:0000287 ... P38502 15647264
    33504 1tv5:A (2.4) BS01 A26 1.3.5.2 GO:0004152 ... Q08210 16510978 MOAD: Ki~1000nM
    BindingDB: IC50=190546nM
    33505 1tv5:A (2.4) BS02 FMN 1.3.5.2 GO:0004152 ... Q08210 16510978
    33506 1tv9:A (2.0) BS01 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 15458631
    33507 1tv9:A (2.0) BS02 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 15458631
    33508 1tv9:A (2.0) BS03 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 15458631
    33509 1tva:A (2.6) BS01 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 15458631
    33510 1tva:A (2.6) BS02 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 15458631
    33511 1tva:A (2.6) BS03 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 15458631
    33512 1tve:A (3.0) BS01 178 1.1.1.3 GO:0004412 ... P31116 15210149 PDBbind: -logKd/Ki=5.68, IC50=2.1uM
    33513 1tve:B (3.0) BS01 178 1.1.1.3 GO:0004412 ... P31116 15210149
    33514 1tvg:A (1.6) BS01 CA ? GO:0001501 ... Q9Y547 18816799
    33515 1tvk:A (2.89) BS01 GTP 3.6.5.- GO:0000226 ... Q2HJ86 15297674
    33516 1tvk:B (2.89) BS01 GDP ? GO:0000226 ... Q6B856 15297674
    33517 1tvk:B (2.89) BS02 EP ? GO:0000226 ... Q6B856 15297674
    33518 1tvo:A (2.5) BS01 FRZ 2.7.11.24 GO:0000165 ... P28482 16139248 MOAD: Ki=0.14uM
    PDBbind: -logKd/Ki=6.85, Ki=0.14uM
    BindingDB: Ki=310nM, IC50=1200nM, Kd=850nM
    33519 1tvu:A (2.5) BS01 UMP 2.1.1.45 GO:0004799 ... P00469 9514716
    33520 1tvv:A (2.3) BS01 UMP 2.1.1.45 GO:0004799 ... P00469 9514716
    33521 1tvw:A (2.5) BS01 UMP 2.1.1.45 GO:0004799 ... P00469 9514716
    33522 1tw4:A (2.0) BS01 CHD ? GO:0005504 ... P80226 15518556
    33523 1tw4:A (2.0) BS02 CHD ? GO:0005504 ... P80226 15518556
    33524 1tw4:B (2.0) BS01 CHD ? GO:0005504 ... P80226 15518556
    33525 1tw4:B (2.0) BS02 CHD ? GO:0005504 ... P80226 15518556
    33526 1twa:A (3.2) BS01 MN 2.7.7.6 GO:0000428 ... P04050 15537538
    33527 1twa:A (3.2) BS02 MN 2.7.7.6 GO:0000428 ... P04050 15537538
    33528 1twa:A (3.2) BS03 ZN 2.7.7.6 GO:0000428 ... P04050 15537538
    33529 1twa:A (3.2) BS04 ATP 2.7.7.6 GO:0000428 ... P04050 15537538
    33530 1twa:B (3.2) BS01 ATP 2.7.7.6 GO:0000428 ... P08518 15537538
    33531 1twa:B (3.2) BS02 ZN 2.7.7.6 GO:0000428 ... P08518 15537538
    33532 1twa:C (3.2) BS01 ZN 2.7.7.6 GO:0000428 ... P16370 15537538
    33533 1twa:I (3.2) BS01 ZN 2.7.7.6 GO:0000428 ... P27999 15537538
    33534 1twa:I (3.2) BS02 ZN 2.7.7.6 GO:0000428 ... P27999 15537538
    33535 1twa:J (3.2) BS01 ZN 2.7.7.6 GO:0000428 ... P22139 15537538
    33536 1twa:L (3.2) BS01 ZN 2.7.7.6 GO:0000428 ... P40422 15537538
    33537 1twc:A (3.0) BS01 ZN 2.7.7.6 GO:0000428 ... P04050 15537538
    33538 1twc:A (3.0) BS02 MN 2.7.7.6 GO:0000428 ... P04050 15537538
    33539 1twc:A (3.0) BS03 MN 2.7.7.6 GO:0000428 ... P04050 15537538
    33540 1twc:A (3.0) BS04 GTP 2.7.7.6 GO:0000428 ... P04050 15537538
    33541 1twc:B (3.0) BS01 ZN 2.7.7.6 GO:0000428 ... P08518 15537538
    33542 1twc:B (3.0) BS02 GTP 2.7.7.6 GO:0000428 ... P08518 15537538
    33543 1twc:C (3.0) BS01 ZN 2.7.7.6 GO:0000428 ... P16370 15537538
    33544 1twc:I (3.0) BS01 ZN 2.7.7.6 GO:0000428 ... P27999 15537538
    33545 1twc:I (3.0) BS02 ZN 2.7.7.6 GO:0000428 ... P27999 15537538
    33546 1twc:J (3.0) BS01 ZN 2.7.7.6 GO:0000428 ... P22139 15537538
    33547 1twc:L (3.0) BS01 ZN 2.7.7.6 GO:0000428 ... P40422 15537538
    33548 1twf:A (2.3) BS01 ZN 2.7.7.6 GO:0000428 ... P04050 15537538
    33549 1twf:A (2.3) BS02 MN 2.7.7.6 GO:0000428 ... P04050 15537538
    33550 1twf:A (2.3) BS03 MN 2.7.7.6 GO:0000428 ... P04050 15537538
    33551 1twf:A (2.3) BS04 UTP 2.7.7.6 GO:0000428 ... P04050 15537538
    33552 1twf:B (2.3) BS01 ZN 2.7.7.6 GO:0000428 ... P08518 15537538
    33553 1twf:B (2.3) BS02 UTP 2.7.7.6 GO:0000428 ... P08518 15537538
    33554 1twf:C (2.3) BS01 ZN 2.7.7.6 GO:0000428 ... P16370 15537538
    33555 1twf:I (2.3) BS01 ZN 2.7.7.6 GO:0000428 ... P27999 15537538
    33556 1twf:I (2.3) BS02 ZN 2.7.7.6 GO:0000428 ... P27999 15537538
    33557 1twf:J (2.3) BS01 ZN 2.7.7.6 GO:0000428 ... P22139 15537538
    33558 1twf:L (2.3) BS01 ZN 2.7.7.6 GO:0000428 ... P40422 15537538
    33559 1twg:A (3.3) BS01 MN 2.7.7.6 GO:0000428 ... P04050 15537538
    33560 1twg:A (3.3) BS02 MN 2.7.7.6 GO:0000428 ... P04050 15537538
    33561 1twg:A (3.3) BS03 ZN 2.7.7.6 GO:0000428 ... P04050 15537538
    33562 1twg:A (3.3) BS04 ZN 2.7.7.6 GO:0000428 ... P04050 15537538
    33563 1twg:A (3.3) BS05 CTP 2.7.7.6 GO:0000428 ... P04050 15537538
    33564 1twg:B (3.3) BS01 ZN 2.7.7.6 GO:0000428 ... P08518 15537538
    33565 1twg:B (3.3) BS02 CTP 2.7.7.6 GO:0000428 ... P08518 15537538
    33566 1twg:C (3.3) BS01 ZN 2.7.7.6 GO:0000428 ... P16370 15537538
    33567 1twg:I (3.3) BS01 ZN 2.7.7.6 GO:0000428 ... P27999 15537538
    33568 1twg:I (3.3) BS02 ZN 2.7.7.6 GO:0000428 ... P27999 15537538
    33569 1twg:J (3.3) BS01 ZN 2.7.7.6 GO:0000428 ... P22139 15537538
    33570 1twg:L (3.3) BS01 ZN 2.7.7.6 GO:0000428 ... P40422 15537538
    33571 1twh:A (3.4) BS01 MN 2.7.7.6 GO:0000428 ... P04050 15537538
    33572 1twh:A (3.4) BS02 MN 2.7.7.6 GO:0000428 ... P04050 15537538
    33573 1twh:A (3.4) BS03 ZN 2.7.7.6 GO:0000428 ... P04050 15537538
    33574 1twh:A (3.4) BS04 ZN 2.7.7.6 GO:0000428 ... P04050 15537538
    33575 1twh:A (3.4) BS05 ATP 2.7.7.6 GO:0000428 ... P04050 15537538
    33576 1twh:B (3.4) BS01 ATP 2.7.7.6 GO:0000428 ... P08518 15537538
    33577 1twh:B (3.4) BS02 ZN 2.7.7.6 GO:0000428 ... P08518 15537538
    33578 1twh:C (3.4) BS01 ZN 2.7.7.6 GO:0000428 ... P16370 15537538
    33579 1twh:I (3.4) BS01 ZN 2.7.7.6 GO:0000428 ... P27999 15537538
    33580 1twh:I (3.4) BS02 ZN 2.7.7.6 GO:0000428 ... P27999 15537538
    33581 1twh:J (3.4) BS01 ZN 2.7.7.6 GO:0000428 ... P22139 15537538
    33582 1twh:L (3.4) BS01 ZN 2.7.7.6 GO:0000428 ... P40422 15537538
    33583 1tww:A (2.5) BS01 HH2 2.5.1.15 GO:0004156 ... Q81VW8 15341734
    33584 1tww:B (2.5) BS01 HH2 2.5.1.15 GO:0004156 ... Q81VW8 15341734
    33585 1twz:A (2.75) BS01 PMM 2.5.1.15 GO:0004156 ... Q81VW8 15341734
    33586 1twz:B (2.75) BS01 PMM 2.5.1.15 GO:0004156 ... Q81VW8 15341734
    33587 1tx0:A (2.15) BS01 PT1 2.5.1.15 GO:0004156 ... Q81VW8 15341734
    33588 1tx0:B (2.15) BS01 PT1 2.5.1.15 GO:0004156 ... Q81VW8 15341734
    33589 1tx2:A (1.83) BS01 680 2.5.1.15 GO:0004156 ... Q81VW8 15341734
    33590 1tx2:B (1.83) BS01 680 2.5.1.15 GO:0004156 ... Q81VW8 15341734
    33591 1tx4:B (1.65) BS01 MG 3.6.5.2 GO:0000902 ... P61586 9338791
    33592 1tx4:B (1.65) BS02 ALF 3.6.5.2 GO:0000902 ... P61586 9338791
    33593 1tx4:B (1.65) BS03 GDP 3.6.5.2 GO:0000902 ... P61586 9338791
    33594 1tx6:A (2.2) BS01 CA 3.4.21.4 GO:0004252 ... P00761 15381428
    33595 1tx6:B (2.2) BS01 CA 3.4.21.4 GO:0004252 ... P00761 15381428
    33596 1tx6:C (2.2) BS01 CA 3.4.21.4 GO:0004252 ... P00761 15381428
    33597 1tx6:D (2.2) BS01 CA 3.4.21.4 GO:0004252 ... P00761 15381428
    33598 1tx7:A (1.75) BS01 CA 3.4.21.4 GO:0004175 ... P00760 11738605
    33599 1tx7:A (1.75) BS02 4CM 3.4.21.4 GO:0004175 ... P00760 11738605 MOAD: Ki=25uM
    PDBbind: -logKd/Ki=4.60, Ki=25uM
    33600 1tx8:A (1.7) BS01 CA 3.4.21.4 GO:0004175 ... P00760 15380220

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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