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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    30801 1s4i:C (1.8) BS01 ZN 1.15.1.1 GO:0004784 ... O31851 15897454
    30802 1s4i:C (1.8) BS02 ZN 1.15.1.1 GO:0004784 ... O31851 15897454
    30803 1s4i:D (1.8) BS01 ZN 1.15.1.1 GO:0004784 ... O31851 15897454
    30804 1s4i:D (1.8) BS02 ZN 1.15.1.1 GO:0004784 ... O31851 15897454
    30805 1s4o:A (2.01) BS01 MN 2.4.1.- GO:0000030 ... P27809 14752117
    30806 1s4o:A (2.01) BS02 GDP 2.4.1.- GO:0000030 ... P27809 14752117
    30807 1s4o:B (2.01) BS01 MN 2.4.1.- GO:0000030 ... P27809 14752117
    30808 1s4o:B (2.01) BS02 GDP 2.4.1.- GO:0000030 ... P27809 14752117
    30809 1s4p:A (2.01) BS01 MMA 2.4.1.- GO:0000030 ... P27809 14752117
    30810 1s4p:A (2.01) BS02 MN 2.4.1.- GO:0000030 ... P27809 14752117
    30811 1s4p:A (2.01) BS03 GDP 2.4.1.- GO:0000030 ... P27809 14752117
    30812 1s4p:B (2.01) BS01 MMA 2.4.1.- GO:0000030 ... P27809 14752117
    30813 1s4p:B (2.01) BS02 MN 2.4.1.- GO:0000030 ... P27809 14752117
    30814 1s4p:B (2.01) BS03 GDP 2.4.1.- GO:0000030 ... P27809 14752117
    30815 1s50:A (1.65) BS01 GLU ? GO:0015276 ... P42260 15721240 MOAD: Ki=1.4uM
    PDBbind: -logKd/Ki=7.20, Ki=0.063uM
    30816 1s51:A (2.0) BS01 RET ? GO:0005216 ... P02945 14982414
    30817 1s51:B (2.0) BS01 RET ? GO:0005216 ... P02945 14982414
    30818 1s52:A (2.3) BS01 RET ? GO:0005216 ... P02945 14982414
    30819 1s52:B (2.3) BS01 RET ? GO:0005216 ... P02945 14982414
    30820 1s53:A (2.0) BS01 RET ? GO:0005216 ... P02945 14982414
    30821 1s53:B (2.0) BS01 RET ? GO:0005216 ... P02945 14982414
    30822 1s54:A (2.2) BS01 RET ? GO:0005216 ... P02945 14982414
    30823 1s54:B (2.2) BS01 RET ? GO:0005216 ... P02945 14982414
    30824 1s56:A (2.43) BS01 HEC ? GO:0005344 ... P9WN25 15016811
    30825 1s56:A (2.43) BS02 XE ? GO:0005344 ... P9WN25 15016811
    30826 1s56:A (2.43) BS03 XE ? GO:0005344 ... P9WN25 15016811
    30827 1s56:A (2.43) BS04 XE ? GO:0005344 ... P9WN25 15016811
    30828 1s56:B (2.43) BS01 HEM ? GO:0005344 ... P9WN25 15016811
    30829 1s56:B (2.43) BS02 XE ? GO:0005344 ... P9WN25 15016811
    30830 1s56:B (2.43) BS03 XE ? GO:0005344 ... P9WN25 15016811
    30831 1s5d:D (1.75) BS01 GAL ? GO:0005515 ... P01556 15049684
    30832 1s5d:E (1.75) BS01 GAL ? GO:0005515 ... P01556 15049684
    30833 1s5d:F (1.75) BS01 GAL ? GO:0005515 ... P01556 15049684
    30834 1s5d:G (1.75) BS01 GAL ? GO:0005515 ... P01556 15049684
    30835 1s5d:H (1.75) BS01 GAL ? GO:0005515 ... P01556 15049684
    30836 1s5e:D (1.9) BS01 GAL ? GO:0005515 ... P01556 15049684
    30837 1s5e:J (1.9) BS01 GAL ? GO:0005515 ... P01556 15049684
    30838 1s5f:D (2.6) BS01 GAL ? GO:0005515 ... P01556 15049684
    30839 1s5f:E (2.6) BS01 GAL ? GO:0005515 ... P01556 15049684
    30840 1s5f:F (2.6) BS01 GAL ? GO:0005515 ... P01556 15049684
    30841 1s5f:G (2.6) BS01 GAL ? GO:0005515 ... P01556 15049684
    30842 1s5f:H (2.6) BS01 GAL ? GO:0005515 ... P01556 15049684
    30843 1s5g:A (3.1) BS01 ADP ? GO:0003774 ... P24733 15184651
    30844 1s5g:Y (3.1) BS01 MG ? GO:0005509 ... P13543 15184651
    30845 1s5g:Z (3.1) BS01 CA ? GO:0005509 ... P07291 15184651
    30846 1s5l:A (3.5) BS01 FE 1.10.3.9 GO:0005506 ... P0A444 14764885
    30847 1s5l:A (3.5) BS02 BCT 1.10.3.9 GO:0005506 ... P0A444 14764885
    30848 1s5l:A (3.5) BS03 OEC 1.10.3.9 GO:0005506 ... P0A444 14764885
    30849 1s5l:A (3.5) BS04 CLA 1.10.3.9 GO:0005506 ... P0A444 14764885
    30850 1s5l:A (3.5) BS05 CLA 1.10.3.9 GO:0005506 ... P0A444 14764885
    30851 1s5l:A (3.5) BS06 CLA 1.10.3.9 GO:0005506 ... P0A444 14764885
    30852 1s5l:A (3.5) BS07 PHO 1.10.3.9 GO:0005506 ... P0A444 14764885
    30853 1s5l:A (3.5) BS08 CLA 1.10.3.9 GO:0005506 ... P0A444 14764885
    30854 1s5l:A (3.5) BS09 CLA 1.10.3.9 GO:0005506 ... P0A444 14764885
    30855 1s5l:A (3.5) BS10 BCT 1.10.3.9 GO:0005506 ... P0A444 14764885
    30856 1s5l:A (3.5) BS11 PHO 1.10.3.9 GO:0005506 ... P0A444 14764885
    30857 1s5l:B (3.5) BS01 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30858 1s5l:B (3.5) BS02 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30859 1s5l:B (3.5) BS03 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30860 1s5l:B (3.5) BS04 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30861 1s5l:B (3.5) BS05 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30862 1s5l:B (3.5) BS06 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30863 1s5l:B (3.5) BS07 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30864 1s5l:B (3.5) BS08 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30865 1s5l:B (3.5) BS09 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30866 1s5l:B (3.5) BS10 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30867 1s5l:B (3.5) BS11 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30868 1s5l:B (3.5) BS12 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30869 1s5l:B (3.5) BS13 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30870 1s5l:B (3.5) BS14 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30871 1s5l:B (3.5) BS15 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30872 1s5l:B (3.5) BS16 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30873 1s5l:C (3.5) BS01 CLA ? GO:0005737 ... Q8DIF8 14764885
    30874 1s5l:C (3.5) BS02 CLA ? GO:0005737 ... Q8DIF8 14764885
    30875 1s5l:C (3.5) BS03 CLA ? GO:0005737 ... Q8DIF8 14764885
    30876 1s5l:C (3.5) BS04 CLA ? GO:0005737 ... Q8DIF8 14764885
    30877 1s5l:C (3.5) BS05 CLA ? GO:0005737 ... Q8DIF8 14764885
    30878 1s5l:C (3.5) BS06 CLA ? GO:0005737 ... Q8DIF8 14764885
    30879 1s5l:C (3.5) BS07 CLA ? GO:0005737 ... Q8DIF8 14764885
    30880 1s5l:C (3.5) BS08 CLA ? GO:0005737 ... Q8DIF8 14764885
    30881 1s5l:C (3.5) BS09 CLA ? GO:0005737 ... Q8DIF8 14764885
    30882 1s5l:C (3.5) BS10 CLA ? GO:0005737 ... Q8DIF8 14764885
    30883 1s5l:C (3.5) BS11 CLA ? GO:0005737 ... Q8DIF8 14764885
    30884 1s5l:C (3.5) BS12 CLA ? GO:0005737 ... Q8DIF8 14764885
    30885 1s5l:C (3.5) BS13 CLA ? GO:0005737 ... Q8DIF8 14764885
    30886 1s5l:C (3.5) BS14 CLA ? GO:0005737 ... Q8DIF8 14764885
    30887 1s5l:D (3.5) BS01 FE 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    30888 1s5l:D (3.5) BS02 CLA 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    30889 1s5l:D (3.5) BS03 CLA 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    30890 1s5l:D (3.5) BS04 PHO 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    30891 1s5l:D (3.5) BS05 CLA 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    30892 1s5l:D (3.5) BS06 BCT 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    30893 1s5l:D (3.5) BS07 CLA 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    30894 1s5l:D (3.5) BS08 PHO 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    30895 1s5l:D (3.5) BS09 CLA 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    30896 1s5l:E (3.5) BS01 HEC ? GO:0005506 ... Q8DIP0 14764885
    30897 1s5l:F (3.5) BS01 HEC ? GO:0005506 ... Q8DIN9 14764885
    30898 1s5l:H (3.5) BS01 CLA ? GO:0009523 ... Q8DJ43 14764885
    30899 1s5l:H (3.5) BS02 CLA ? GO:0009523 ... Q8DJ43 14764885
    30900 1s5l:H (3.5) BS03 CLA ? GO:0009523 ... Q8DJ43 14764885
    30901 1s5l:H (3.5) BS04 CLA ? GO:0009523 ... Q8DJ43 14764885
    30902 1s5l:K (3.5) BS01 CLA ? GO:0009523 ... Q9F1K9 14764885
    30903 1s5l:K (3.5) BS02 CLA ? GO:0009523 ... Q9F1K9 14764885
    30904 1s5l:M (3.5) BS01 CLA ? GO:0005737 ... Q8DHA7 14764885
    30905 1s5l:V (3.5) BS01 HEC ? GO:0005506 ... P0A386 14764885
    30906 1s5l:a (3.5) BS01 FE 1.10.3.9 GO:0005506 ... P0A444 14764885
    30907 1s5l:a (3.5) BS02 OEC 1.10.3.9 GO:0005506 ... P0A444 14764885
    30908 1s5l:a (3.5) BS03 CLA 1.10.3.9 GO:0005506 ... P0A444 14764885
    30909 1s5l:a (3.5) BS04 CLA 1.10.3.9 GO:0005506 ... P0A444 14764885
    30910 1s5l:a (3.5) BS05 PHO 1.10.3.9 GO:0005506 ... P0A444 14764885
    30911 1s5l:a (3.5) BS06 CLA 1.10.3.9 GO:0005506 ... P0A444 14764885
    30912 1s5l:a (3.5) BS07 CLA 1.10.3.9 GO:0005506 ... P0A444 14764885
    30913 1s5l:a (3.5) BS08 BCT 1.10.3.9 GO:0005506 ... P0A444 14764885
    30914 1s5l:a (3.5) BS09 CLA 1.10.3.9 GO:0005506 ... P0A444 14764885
    30915 1s5l:a (3.5) BS10 CLA 1.10.3.9 GO:0005506 ... P0A444 14764885
    30916 1s5l:a (3.5) BS11 PHO 1.10.3.9 GO:0005506 ... P0A444 14764885
    30917 1s5l:b (3.5) BS01 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30918 1s5l:b (3.5) BS02 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30919 1s5l:b (3.5) BS03 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30920 1s5l:b (3.5) BS04 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30921 1s5l:b (3.5) BS05 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30922 1s5l:b (3.5) BS06 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30923 1s5l:b (3.5) BS07 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30924 1s5l:b (3.5) BS08 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30925 1s5l:b (3.5) BS09 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30926 1s5l:b (3.5) BS10 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30927 1s5l:b (3.5) BS11 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30928 1s5l:b (3.5) BS12 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30929 1s5l:b (3.5) BS13 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30930 1s5l:b (3.5) BS14 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30931 1s5l:b (3.5) BS15 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30932 1s5l:b (3.5) BS16 CLA ? GO:0009521 ... Q8DIQ1 14764885
    30933 1s5l:c (3.5) BS01 CLA ? GO:0005737 ... Q8DIF8 14764885
    30934 1s5l:c (3.5) BS02 CLA ? GO:0005737 ... Q8DIF8 14764885
    30935 1s5l:c (3.5) BS03 CLA ? GO:0005737 ... Q8DIF8 14764885
    30936 1s5l:c (3.5) BS04 CLA ? GO:0005737 ... Q8DIF8 14764885
    30937 1s5l:c (3.5) BS05 CLA ? GO:0005737 ... Q8DIF8 14764885
    30938 1s5l:c (3.5) BS06 CLA ? GO:0005737 ... Q8DIF8 14764885
    30939 1s5l:c (3.5) BS07 CLA ? GO:0005737 ... Q8DIF8 14764885
    30940 1s5l:c (3.5) BS08 CLA ? GO:0005737 ... Q8DIF8 14764885
    30941 1s5l:c (3.5) BS09 CLA ? GO:0005737 ... Q8DIF8 14764885
    30942 1s5l:c (3.5) BS10 CLA ? GO:0005737 ... Q8DIF8 14764885
    30943 1s5l:c (3.5) BS11 CLA ? GO:0005737 ... Q8DIF8 14764885
    30944 1s5l:c (3.5) BS12 CLA ? GO:0005737 ... Q8DIF8 14764885
    30945 1s5l:c (3.5) BS13 CLA ? GO:0005737 ... Q8DIF8 14764885
    30946 1s5l:c (3.5) BS14 CLA ? GO:0005737 ... Q8DIF8 14764885
    30947 1s5l:d (3.5) BS01 FE 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    30948 1s5l:d (3.5) BS02 CLA 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    30949 1s5l:d (3.5) BS03 PHO 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    30950 1s5l:d (3.5) BS04 CLA 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    30951 1s5l:d (3.5) BS05 BCT 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    30952 1s5l:d (3.5) BS06 CLA 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    30953 1s5l:d (3.5) BS07 CLA 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    30954 1s5l:d (3.5) BS08 PHO 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    30955 1s5l:d (3.5) BS09 CLA 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    30956 1s5l:e (3.5) BS01 HEC ? GO:0005506 ... Q8DIP0 14764885
    30957 1s5l:f (3.5) BS01 HEC ? GO:0005506 ... Q8DIN9 14764885
    30958 1s5l:h (3.5) BS01 CLA ? GO:0009523 ... Q8DJ43 14764885
    30959 1s5l:h (3.5) BS02 CLA ? GO:0009523 ... Q8DJ43 14764885
    30960 1s5l:h (3.5) BS03 CLA ? GO:0009523 ... Q8DJ43 14764885
    30961 1s5l:h (3.5) BS04 CLA ? GO:0009523 ... Q8DJ43 14764885
    30962 1s5l:i (3.5) BS01 CLA ? GO:0005737 ... Q8DJZ6 14764885
    30963 1s5l:k (3.5) BS01 CLA ? GO:0009523 ... Q9F1K9 14764885
    30964 1s5l:k (3.5) BS02 CLA ? GO:0009523 ... Q9F1K9 14764885
    30965 1s5l:m (3.5) BS01 CLA ? GO:0005737 ... Q8DHA7 14764885
    30966 1s5l:v (3.5) BS01 HEC ? GO:0005506 ... P0A386 14764885
    30967 1s5m:A (0.98) BS01 GLC 5.3.1.5 GO:0000287 ... P15587 15157080
    30968 1s5m:A (0.98) BS02 MN 5.3.1.5 GO:0000287 ... P15587 15157080
    30969 1s5m:A (0.98) BS03 MN 5.3.1.5 GO:0000287 ... P15587 15157080
    30970 1s5n:A (0.95) BS01 XYL 5.3.1.5 GO:0000287 ... P15587 15157080
    30971 1s5n:A (0.95) BS02 MN 5.3.1.5 GO:0000287 ... P15587 15157080
    30972 1s5n:A (0.95) BS03 MN 5.3.1.5 GO:0000287 ... P15587 15157080
    30973 1s5o:A (1.8) BS01 152 2.3.1.137
    2.3.1.7
    GO:0003997 ... P43155 15099582
    30974 1s5s:A (1.4) BS01 CA 3.4.21.4 GO:0004252 ... P00761 15005618
    30975 1s5s:A (1.4) BS02 PG3 3.4.21.4 GO:0004252 ... P00761 15005618
    30976 1s5x:A (2.4) BS01 HEM ? GO:0004601 ... P80043 15096204
    30977 1s5x:B (2.4) BS01 HEM ? GO:0004601 ... P80044 15096204
    30978 1s5y:A (2.5) BS01 HEM ? GO:0004601 ... P80043 15096204
    30979 1s5y:B (2.5) BS01 HEM ? GO:0004601 ... P80044 15096204
    30980 1s5y:C (2.5) BS01 HEM ? GO:0004601 ... P80043 15096204
    30981 1s5y:D (2.5) BS01 HEM ? GO:0004601 ... P80044 15096204
    30982 1s5z:A (2.0) BS01 SON 2.7.4.6 GO:0004550 ... P22887 16787337 PDBbind: -logKd/Ki=3.21, Kd=0.62mM
    30983 1s61:A (2.1) BS01 HEM ? GO:0005344 ... P9WN25 15016811
    30984 1s61:B (2.1) BS01 HEM ? GO:0005344 ... P9WN25 15016811
    30985 1s63:A (1.9) BS01 GLC 2.5.1.58
    2.5.1.59
    GO:0004659 ... P49354 15248757
    30986 1s63:A (1.9) BS02 FPP 2.5.1.58
    2.5.1.59
    GO:0004659 ... P49354 15248757 BindingDB: Kd=2.0nM
    30987 1s63:B (1.9) BS01 GLC 2.5.1.58 GO:0003824 ... P49356 15248757
    30988 1s63:B (1.9) BS02 FRU 2.5.1.58 GO:0003824 ... P49356 15248757
    30989 1s63:B (1.9) BS03 ZN 2.5.1.58 GO:0003824 ... P49356 15248757
    30990 1s63:B (1.9) BS04 FPP 2.5.1.58 GO:0003824 ... P49356 15248757
    30991 1s63:B (1.9) BS05 778 2.5.1.58 GO:0003824 ... P49356 15248757 MOAD: Ki=0.9nM
    PDBbind: -logKd/Ki=9.05, Ki=0.9nM
    BindingDB: IC50=2nM
    30992 1s64:B (2.55) BS01 ZN 2.5.1.59 GO:0003824 ... P53610 15248757
    30993 1s64:B (2.55) BS02 778 2.5.1.59 GO:0003824 ... P53610 15248757 PDBbind: -logKd/Ki=8.40, Ki=4nM
    30994 1s64:D (2.55) BS01 ZN 2.5.1.59 GO:0003824 ... P53610 15248757
    30995 1s64:D (2.55) BS02 778 2.5.1.59 GO:0003824 ... P53610 15248757
    30996 1s64:F (2.55) BS01 ZN 2.5.1.59 GO:0003824 ... P53610 15248757
    30997 1s64:F (2.55) BS02 778 2.5.1.59 GO:0003824 ... P53610 15248757
    30998 1s64:H (2.55) BS01 ZN 2.5.1.59 GO:0003824 ... P53610 15248757
    30999 1s64:H (2.55) BS02 778 2.5.1.59 GO:0003824 ... P53610 15248757
    31000 1s64:J (2.55) BS01 ZN 2.5.1.59 GO:0003824 ... P53610 15248757

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218