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BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    25001 1oqu:B (2.0) BS02 FE 1.17.4.1 GO:0004748 ... O69274 15178319
    25002 1oqu:C (2.0) BS01 FE 1.17.4.1 GO:0004748 ... O69274 15178319
    25003 1oqu:C (2.0) BS02 FE 1.17.4.1 GO:0004748 ... O69274 15178319
    25004 1oqu:C (2.0) BS03 FE 1.17.4.1 GO:0004748 ... O69274 15178319
    25005 1oqu:C (2.0) BS04 FE 1.17.4.1 GO:0004748 ... O69274 15178319
    25006 1oqu:C (2.0) BS05 FE 1.17.4.1 GO:0004748 ... O69274 15178319
    25007 1oqu:C (2.0) BS06 OXY 1.17.4.1 GO:0004748 ... O69274 15178319
    25008 1oqu:D (2.0) BS01 FE 1.17.4.1 GO:0004748 ... O69274 15178319
    25009 1oqu:D (2.0) BS02 FE 1.17.4.1 GO:0004748 ... O69274 15178319
    25010 1oqu:D (2.0) BS03 FE 1.17.4.1 GO:0004748 ... O69274 15178319
    25011 1oqu:D (2.0) BS04 OXY 1.17.4.1 GO:0004748 ... O69274 15178319
    25012 1or8:A (2.35) BS01 peptide 2.1.1.319 GO:0001701 ... Q63009 12737817
    25013 1or8:A (2.35) BS02 peptide 2.1.1.319 GO:0001701 ... Q63009 12737817
    25014 1or8:A (2.35) BS03 peptide 2.1.1.319 GO:0001701 ... Q63009 12737817
    25015 1or8:A (2.35) BS04 peptide 2.1.1.319 GO:0001701 ... Q63009 12737817
    25016 1or8:A (2.35) BS05 SAH 2.1.1.319 GO:0001701 ... Q63009 12737817
    25017 1orb:A (2.0) BS01 ACT 2.8.1.1 GO:0003723 ... P00586 8702871
    25018 1ord:A (3.0) BS01 PLP 4.1.1.17 GO:0003824 ... P43099 7563080
    25019 1ord:A (3.0) BS02 PLP 4.1.1.17 GO:0003824 ... P43099 7563080
    25020 1ord:B (3.0) BS01 PLP 4.1.1.17 GO:0003824 ... P43099 7563080
    25021 1ord:B (3.0) BS02 PLP 4.1.1.17 GO:0003824 ... P43099 7563080
    25022 1ore:A (2.1) BS01 AMP 2.4.2.7 GO:0002055 ... P07741 15196008
    25023 1orf:A (2.4) BS01 0G6 3.4.21.78 GO:0001772 ... P12544 12819769
    25024 1orh:A (2.64) BS01 peptide 2.1.1.319 GO:0001701 ... Q63009 12737817
    25025 1orh:A (2.64) BS02 SAH 2.1.1.319 GO:0001701 ... Q63009 12737817
    25026 1ori:A (2.5) BS01 SAH 2.1.1.319 GO:0001701 ... Q63009 12737817
    25027 1oro:A (2.4) BS01 SO4 2.4.2.10 GO:0000287 ... P0A7E3 8620002
    25028 1orw:A (2.84) BS01 PHI 3.4.14.5 GO:0002020 ... P22411 12690074 PDBbind: -logKd/Ki=7.60, Ki=25.1nM
    25029 1orw:A (2.84) BS02 P2Y 3.4.14.5 GO:0002020 ... P22411 12690074 PDBbind: -logKd/Ki=7.60, Ki=25.1nM
    25030 1orw:B (2.84) BS01 PHI 3.4.14.5 GO:0002020 ... P22411 12690074
    25031 1orw:B (2.84) BS02 P2Y 3.4.14.5 GO:0002020 ... P22411 12690074
    25032 1orw:C (2.84) BS01 PHI 3.4.14.5 GO:0002020 ... P22411 12690074
    25033 1orw:C (2.84) BS02 P2Y 3.4.14.5 GO:0002020 ... P22411 12690074
    25034 1orw:D (2.84) BS01 PHI 3.4.14.5 GO:0002020 ... P22411 12690074
    25035 1orw:D (2.84) BS02 P2Y 3.4.14.5 GO:0002020 ... P22411 12690074
    25036 1os1:A (1.8) BS01 CA 4.1.1.49 GO:0000287 ... P22259 12837799
    25037 1os1:A (1.8) BS02 ATP 4.1.1.49 GO:0000287 ... P22259 12837799
    25038 1os1:A (1.8) BS03 PYR 4.1.1.49 GO:0000287 ... P22259 12837799
    25039 1os2:A (2.15) BS01 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25040 1os2:A (2.15) BS02 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25041 1os2:A (2.15) BS03 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25042 1os2:A (2.15) BS04 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25043 1os2:A (2.15) BS05 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25044 1os2:B (2.15) BS01 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25045 1os2:B (2.15) BS02 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25046 1os2:B (2.15) BS03 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25047 1os2:B (2.15) BS04 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25048 1os2:B (2.15) BS05 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25049 1os2:C (2.15) BS01 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25050 1os2:C (2.15) BS02 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25051 1os2:C (2.15) BS03 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25052 1os2:C (2.15) BS04 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25053 1os2:C (2.15) BS05 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25054 1os2:C (2.15) BS06 AZI 3.4.24.65 GO:0004222 ... P39900 12813751
    25055 1os2:D (2.15) BS01 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25056 1os2:D (2.15) BS02 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25057 1os2:D (2.15) BS03 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25058 1os2:D (2.15) BS04 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25059 1os2:D (2.15) BS05 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25060 1os2:E (2.15) BS01 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25061 1os2:E (2.15) BS02 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25062 1os2:E (2.15) BS03 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25063 1os2:E (2.15) BS04 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25064 1os2:E (2.15) BS05 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25065 1os2:F (2.15) BS01 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25066 1os2:F (2.15) BS02 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25067 1os2:F (2.15) BS03 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25068 1os2:F (2.15) BS04 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25069 1os2:F (2.15) BS05 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25070 1os7:A (2.5) BS01 FE2 1.14.11.17 GO:0000908 ... P37610 12741810
    25071 1os7:A (2.5) BS02 AKG 1.14.11.17 GO:0000908 ... P37610 12741810
    25072 1os7:B (2.5) BS01 FE2 1.14.11.17 GO:0000908 ... P37610 12741810
    25073 1os7:B (2.5) BS02 AKG 1.14.11.17 GO:0000908 ... P37610 12741810
    25074 1os7:C (2.5) BS01 FE2 1.14.11.17 GO:0000908 ... P37610 12741810
    25075 1os7:C (2.5) BS02 AKG 1.14.11.17 GO:0000908 ... P37610 12741810
    25076 1os7:D (2.5) BS01 FE2 1.14.11.17 GO:0000908 ... P37610 12741810
    25077 1os7:D (2.5) BS02 AKG 1.14.11.17 GO:0000908 ... P37610 12741810
    25078 1os9:A (1.85) BS01 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25079 1os9:A (1.85) BS02 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25080 1os9:A (1.85) BS03 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25081 1os9:A (1.85) BS04 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25082 1os9:A (1.85) BS05 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25083 1os9:B (1.85) BS01 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25084 1os9:B (1.85) BS02 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25085 1os9:B (1.85) BS03 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25086 1os9:B (1.85) BS04 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25087 1os9:B (1.85) BS05 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25088 1os9:C (1.85) BS01 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25089 1os9:C (1.85) BS02 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25090 1os9:C (1.85) BS03 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25091 1os9:C (1.85) BS04 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25092 1os9:C (1.85) BS05 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25093 1os9:D (1.85) BS01 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25094 1os9:D (1.85) BS02 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25095 1os9:D (1.85) BS03 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25096 1os9:D (1.85) BS04 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25097 1os9:D (1.85) BS05 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25098 1os9:E (1.85) BS01 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25099 1os9:E (1.85) BS02 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25100 1os9:E (1.85) BS03 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25101 1os9:E (1.85) BS04 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25102 1os9:E (1.85) BS05 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25103 1os9:F (1.85) BS01 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25104 1os9:F (1.85) BS02 ZN 3.4.24.65 GO:0004222 ... P39900 12813751
    25105 1os9:F (1.85) BS03 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25106 1os9:F (1.85) BS04 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25107 1os9:F (1.85) BS05 CA 3.4.24.65 GO:0004222 ... P39900 12813751
    25108 1ose:A (2.3) BS01 AC1 3.2.1.1 GO:0003824 ... P00690 8681972
    25109 1ose:A (2.3) BS02 GLC 3.2.1.1 GO:0003824 ... P00690 8681972
    25110 1ose:A (2.3) BS03 AC1 3.2.1.1 GO:0003824 ... P00690 8681972
    25111 1ose:A (2.3) BS04 BGC 3.2.1.1 GO:0003824 ... P00690 8681972
    25112 1ose:A (2.3) BS05 CA 3.2.1.1 GO:0003824 ... P00690 8681972
    25113 1osg:A (3.0) BS01 peptide ? GO:0005164 ... Q9Y275 12755599
    25114 1osg:B (3.0) BS01 peptide ? GO:0005164 ... Q9Y275 12755599
    25115 1osg:C (3.0) BS01 peptide ? GO:0005164 ... Q9Y275 12755599
    25116 1osg:C (3.0) BS02 peptide ? GO:0005164 ... Q9Y275 12755599
    25117 1osg:D (3.0) BS01 peptide ? GO:0005164 ... Q9Y275 12755599
    25118 1osg:E (3.0) BS01 peptide ? GO:0005164 ... Q9Y275 12755599
    25119 1osg:F (3.0) BS01 peptide ? GO:0005164 ... Q9Y275 12755599
    25120 1ot1:A (2.0) BS01 BGC 2.4.1.19 GO:0003824 ... P43379 12706817
    25121 1ot1:A (2.0) BS02 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25122 1ot1:A (2.0) BS03 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25123 1ot1:A (2.0) BS04 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25124 1ot1:A (2.0) BS05 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25125 1ot1:A (2.0) BS06 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25126 1ot1:A (2.0) BS07 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25127 1ot1:A (2.0) BS08 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25128 1ot1:A (2.0) BS09 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25129 1ot1:A (2.0) BS10 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25130 1ot1:A (2.0) BS11 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25131 1ot1:A (2.0) BS12 CA 2.4.1.19 GO:0003824 ... P43379 12706817
    25132 1ot1:A (2.0) BS13 CA 2.4.1.19 GO:0003824 ... P43379 12706817
    25133 1ot1:A (2.0) BS14 CA 2.4.1.19 GO:0003824 ... P43379 12706817
    25134 1ot2:A (2.1) BS01 BGC 2.4.1.19 GO:0003824 ... P43379 12706817
    25135 1ot2:A (2.1) BS02 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25136 1ot2:A (2.1) BS03 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25137 1ot2:A (2.1) BS04 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25138 1ot2:A (2.1) BS05 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25139 1ot2:A (2.1) BS06 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25140 1ot2:A (2.1) BS07 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25141 1ot2:A (2.1) BS08 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25142 1ot2:A (2.1) BS09 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25143 1ot2:A (2.1) BS10 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25144 1ot2:A (2.1) BS11 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25145 1ot2:A (2.1) BS12 CA 2.4.1.19 GO:0003824 ... P43379 12706817
    25146 1ot2:A (2.1) BS13 GLC 2.4.1.19 GO:0003824 ... P43379 12706817
    25147 1ot2:A (2.1) BS14 CA 2.4.1.19 GO:0003824 ... P43379 12706817
    25148 1ot2:A (2.1) BS15 CA 2.4.1.19 GO:0003824 ... P43379 12706817
    25149 1ot3:A (2.5) BS01 THM 2.7.1.145 GO:0004136 ... Q9XZT6 12741827
    25150 1ot3:B (2.5) BS01 THM 2.7.1.145 GO:0004136 ... Q9XZT6 12741827
    25151 1ot3:C (2.5) BS01 THM 2.7.1.145 GO:0004136 ... Q9XZT6 12741827
    25152 1ot3:D (2.5) BS01 THM 2.7.1.145 GO:0004136 ... Q9XZT6 12741827
    25153 1ot3:E (2.5) BS01 THM 2.7.1.145 GO:0004136 ... Q9XZT6 12741827
    25154 1ot3:F (2.5) BS01 THM 2.7.1.145 GO:0004136 ... Q9XZT6 12741827
    25155 1ot3:G (2.5) BS01 THM 2.7.1.145 GO:0004136 ... Q9XZT6 12741827
    25156 1ot3:H (2.5) BS01 THM 2.7.1.145 GO:0004136 ... Q9XZT6 12741827
    25157 1otc:A (2.8) BS01 dna ? GO:0000723 ... P29549 9875850
    25158 1otc:B (2.8) BS01 dna ? GO:0000781 ... P16458 9875850
    25159 1oth:A (1.85) BS01 PAO 2.1.3.3 GO:0000050 ... P00480 9852088 PDBbind: -logKd/Ki=7.00, Ki=0.1uM
    BindingDB: Ki=100nM
    25160 1ots:A (2.51) BS01 CL ? GO:0005247 ... P37019 12649487
    25161 1ots:A (2.51) BS02 CL ? GO:0005247 ... P37019 12649487
    25162 1ots:B (2.51) BS01 CL ? GO:0005247 ... P37019 12649487
    25163 1ots:B (2.51) BS02 CL ? GO:0005247 ... P37019 12649487
    25164 1ott:A (3.0) BS01 CL ? GO:0005247 ... P37019 12649487
    25165 1ott:A (3.0) BS02 CL ? GO:0005247 ... P37019 12649487
    25166 1ott:A (3.0) BS03 CL ? GO:0005247 ... P37019 12649487
    25167 1ott:B (3.0) BS01 CL ? GO:0005247 ... P37019 12649487
    25168 1ott:B (3.0) BS02 CL ? GO:0005247 ... P37019 12649487
    25169 1ott:B (3.0) BS03 CL ? GO:0005247 ... P37019 12649487
    25170 1otu:A (3.3) BS01 CL ? GO:0005247 ... P37019 12649487
    25171 1otu:A (3.3) BS02 CL ? GO:0005247 ... P37019 12649487
    25172 1otu:A (3.3) BS03 CL ? GO:0005247 ... P37019 12649487
    25173 1otu:B (3.3) BS01 CL ? GO:0005247 ... P37019 12649487
    25174 1otu:B (3.3) BS02 CL ? GO:0005247 ... P37019 12649487
    25175 1oty:A (2.5) BS01 6MP 2.4.2.1 GO:0003824 ... P0ABP8 14700625
    25176 1oty:B (2.5) BS01 6MP 2.4.2.1 GO:0003824 ... P0ABP8 14700625
    25177 1oty:C (2.5) BS01 6MP 2.4.2.1 GO:0003824 ... P0ABP8 14700625
    25178 1ou4:A (2.5) BS01 6MP 2.4.2.1 GO:0003824 ... P0ABP8 14700625
    25179 1ou4:B (2.5) BS01 6MP 2.4.2.1 GO:0003824 ... P0ABP8 14700625
    25180 1ou4:C (2.5) BS01 6MP 2.4.2.1 GO:0003824 ... P0ABP8 14700625
    25181 1ou6:A (2.07) BS01 168 2.3.1.9 GO:0003985 ... P07097 N/A
    25182 1ou6:B (2.07) BS01 168 2.3.1.9 GO:0003985 ... P07097 N/A
    25183 1ouk:A (2.5) BS01 084 2.7.11.24 GO:0000077 ... Q16539 12897767 MOAD: ic50=0.13nM
    PDBbind: -logKd/Ki=9.89, IC50=0.13nM
    BindingDB: IC50=110nM
    25184 1oum:A (2.4) BS01 TAL 2.4.2.1 GO:0003824 ... P0ABP8 14700625
    25185 1oum:B (2.4) BS01 TAL 2.4.2.1 GO:0003824 ... P0ABP8 14700625
    25186 1oum:C (2.4) BS01 TAL 2.4.2.1 GO:0003824 ... P0ABP8 14700625
    25187 1out:A (2.3) BS01 HEM ? GO:0004601 ... P02019 8683580
    25188 1out:B (2.3) BS01 HEM ? GO:0004601 ... P02142 8683580
    25189 1ouu:A (2.5) BS01 HEM ? GO:0004601 ... P02019 8683580
    25190 1ouu:B (2.5) BS01 HEM ? GO:0004601 ... P02142 8683580
    25191 1ouu:C (2.5) BS01 HEM ? GO:0004601 ... P02019 8683580
    25192 1ouu:D (2.5) BS01 HEM ? GO:0004601 ... P02142 8683580
    25193 1ouy:A (2.5) BS01 094 2.7.11.24 GO:0000077 ... Q16539 12897767 MOAD: ic50=4.3nM
    PDBbind: -logKd/Ki=8.37, IC50=4.3nM
    25194 1ouz:A (2.41) BS01 dna ? GO:0000976 ... P0A6X7 12842466 PDBbind: Kd=15nM
    25195 1ouz:A (2.41) BS02 dna ? GO:0000976 ... P0A6X7 12842466 PDBbind: Kd=15nM
    25196 1ouz:A (2.41) BS03 dna ? GO:0000976 ... P0A6X7 12842466 PDBbind: Kd=15nM
    25197 1ouz:B (2.41) BS01 dna ? GO:0003677 ... P0A6Y1 12842466 PDBbind: Kd=15nM
    25198 1ouz:B (2.41) BS02 dna ? GO:0003677 ... P0A6Y1 12842466 PDBbind: Kd=15nM
    25199 1ov4:A (2.7) BS01 SO4 2.8.2.14
    2.8.2.2
    GO:0004027 ... Q06520 14573603
    25200 1ov4:A (2.7) BS02 AOX 2.8.2.14
    2.8.2.2
    GO:0004027 ... Q06520 14573603

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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