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BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1801 1b46:A (1.8) BS01 peptide ? GO:0015031 ... P06202 10438628
    1802 1b48:A (2.6) BS01 HAG 2.5.1.18 GO:0004364 ... P24472 10508391
    1803 1b48:A (2.6) BS02 GSH 2.5.1.18 GO:0004364 ... P24472 10508391
    1804 1b48:B (2.6) BS01 GSH 2.5.1.18 GO:0004364 ... P24472 10508391
    1805 1b4d:A (2.0) BS01 CRA 2.4.1.1 GO:0000166 ... P00489 10211820 MOAD: Ki=15.6uM
    PDBbind: -logKd/Ki=4.81, Ki=15.6uM
    BindingDB: Ki=16000nM
    1806 1b4d:A (2.0) BS02 PLP 2.4.1.1 GO:0000166 ... P00489 10211820
    1807 1b4d:A (2.0) BS03 IMP 2.4.1.1 GO:0000166 ... P00489 10211820
    1808 1b4e:A (2.0) BS01 ZN 4.2.1.24 GO:0000287 ... P0ACB2 10194344
    1809 1b4e:A (2.0) BS02 ZN 4.2.1.24 GO:0000287 ... P0ACB2 10194344
    1810 1b4e:A (2.0) BS03 SHF 4.2.1.24 GO:0000287 ... P0ACB2 10194344 BindingDB: Ki=2.200e+6nM
    1811 1b4h:A (1.9) BS01 peptide ? GO:0015031 ... P06202 10422831
    1812 1b4k:A (1.67) BS01 SHF 4.2.1.24 GO:0004655 ... Q59643 10356331
    1813 1b4k:B (1.67) BS01 SHF 4.2.1.24 GO:0004655 ... Q59643 10356331
    1814 1b4l:A (1.8) BS01 CU 1.15.1.1 GO:0004784 ... P00445 10026301
    1815 1b4l:A (1.8) BS02 ZN 1.15.1.1 GO:0004784 ... P00445 10026301
    1816 1b4p:A (1.7) BS01 GPS 2.5.1.18 GO:0004364 ... P08010 N/A
    1817 1b4p:A (1.7) BS02 GPS 2.5.1.18 GO:0004364 ... P08010 N/A
    1818 1b4q:A (-1.00) BS01 GSH ? GO:0005515 ... P35754 9860827
    1819 1b4s:A (2.5) BS01 PO4 2.7.4.6 GO:0004550 ... P22887 10200157
    1820 1b4s:A (2.5) BS02 ADP 2.7.4.6 GO:0004550 ... P22887 10200157
    1821 1b4s:B (2.5) BS01 PO4 2.7.4.6 GO:0004550 ... P22887 10200157
    1822 1b4s:B (2.5) BS02 ADP 2.7.4.6 GO:0004550 ... P22887 10200157
    1823 1b4s:C (2.5) BS01 PO4 2.7.4.6 GO:0004550 ... P22887 10200157
    1824 1b4s:C (2.5) BS02 ADP 2.7.4.6 GO:0004550 ... P22887 10200157
    1825 1b4t:A (1.8) BS01 CU 1.15.1.1 GO:0004784 ... P00445 10026301
    1826 1b4t:A (1.8) BS02 ZN 1.15.1.1 GO:0004784 ... P00445 10026301
    1827 1b4t:A (1.8) BS03 CL 1.15.1.1 GO:0004784 ... P00445 10026301
    1828 1b4v:A (1.5) BS01 FAD 1.1.3.6
    5.3.3.1
    GO:0004769 ... P12676 10194345
    1829 1b4w:A (2.6) BS01 BOG 3.1.1.4 GO:0004623 ... O42187 10728829
    1830 1b4w:D (2.6) BS01 BOG 3.1.1.4 GO:0004623 ... O42187 10728829
    1831 1b4x:A (2.45) BS01 PLP 2.6.1.1 GO:0003824 ... P00509 10708649
    1832 1b4z:A (1.75) BS01 peptide ? GO:0015031 ... P06202 10438628
    1833 1b51:A (1.8) BS01 peptide ? GO:0015031 ... P06202 10438628
    1834 1b52:A (2.3) BS01 peptide ? GO:0015031 ... P06202 10438628
    1835 1b54:A (2.1) BS01 PLP ? GO:0005575 ... P38197 12499548
    1836 1b57:A (2.0) BS01 ZN 4.1.2.13 GO:0004332 ... P0AB71 10080900
    1837 1b57:A (2.0) BS02 ZN 4.1.2.13 GO:0004332 ... P0AB71 10080900
    1838 1b57:A (2.0) BS03 ZN 4.1.2.13 GO:0004332 ... P0AB71 10080900
    1839 1b57:A (2.0) BS04 PGH 4.1.2.13 GO:0004332 ... P0AB71 10080900 PDBbind: -logKd/Ki=8.00, Ki=0.01uM
    1840 1b57:B (2.0) BS01 ZN 4.1.2.13 GO:0004332 ... P0AB71 10080900
    1841 1b57:B (2.0) BS02 ZN 4.1.2.13 GO:0004332 ... P0AB71 10080900
    1842 1b57:B (2.0) BS03 ZN 4.1.2.13 GO:0004332 ... P0AB71 10080900
    1843 1b57:B (2.0) BS04 PGH 4.1.2.13 GO:0004332 ... P0AB71 10080900 PDBbind: -logKd/Ki=8.00, Ki=0.01uM
    1844 1b58:A (1.8) BS01 peptide ? GO:0015031 ... P06202 10438628
    1845 1b5h:A (1.9) BS01 peptide ? GO:0015031 ... P06202 10422831
    1846 1b5i:A (1.9) BS01 peptide ? GO:0015031 ... P06202 10438628
    1847 1b5j:A (1.8) BS01 peptide ? GO:0015031 ... P06202 10438628
    1848 1b5o:A (2.2) BS01 PLP 2.6.1.1
    2.6.1.78
    GO:0003824 ... Q56232 11432784
    1849 1b5o:B (2.2) BS01 PLP 2.6.1.1
    2.6.1.78
    GO:0003824 ... Q56232 11432784
    1850 1b5p:A (1.8) BS01 PLP 2.6.1.1
    2.6.1.78
    GO:0003824 ... Q56232 11432784
    1851 1b5p:B (1.8) BS01 PLP 2.6.1.1
    2.6.1.78
    GO:0003824 ... Q56232 11432784
    1852 1b5q:A (1.9) BS01 FAD 1.5.3.14
    1.5.3.15
    GO:0006598 ... O64411 10368296
    1853 1b5q:A (1.9) BS02 MD2 1.5.3.14
    1.5.3.15
    GO:0006598 ... O64411 10368296 MOAD: Ki=550nM
    1854 1b5q:B (1.9) BS01 FAD 1.5.3.14
    1.5.3.15
    GO:0006598 ... O64411 10368296
    1855 1b5q:B (1.9) BS02 MD2 1.5.3.14
    1.5.3.15
    GO:0006598 ... O64411 10368296 MOAD: Ki=550nM
    1856 1b5q:C (1.9) BS01 FAD 1.5.3.14
    1.5.3.15
    GO:0006598 ... O64411 10368296
    1857 1b5q:C (1.9) BS02 MD2 1.5.3.14
    1.5.3.15
    GO:0006598 ... O64411 10368296 MOAD: Ki=550nM
    1858 1b5t:A (2.5) BS01 FAD 1.5.1.54 GO:0004489 ... P0AEZ1 10201405
    1859 1b5t:B (2.5) BS01 FAD 1.5.1.54 GO:0004489 ... P0AEZ1 10201405
    1860 1b5t:C (2.5) BS01 FAD 1.5.1.54 GO:0004489 ... P0AEZ1 10201405
    1861 1b62:A (2.1) BS01 MG ? GO:0005524 ... P23367 10199405
    1862 1b62:A (2.1) BS02 ADP ? GO:0005524 ... P23367 10199405
    1863 1b63:A (1.9) BS01 ANP ? GO:0005524 ... P23367 10199405
    1864 1b66:A (1.9) BS01 ZN 4.2.3.12 GO:0003874 ... P27213 10024455
    1865 1b66:A (1.9) BS02 BIO 4.2.3.12 GO:0003874 ... P27213 10024455
    1866 1b66:B (1.9) BS01 ZN 4.2.3.12 GO:0003874 ... P27213 10024455
    1867 1b66:B (1.9) BS02 BIO 4.2.3.12 GO:0003874 ... P27213 10024455
    1868 1b6a:A (1.6) BS01 CO 3.4.11.18 GO:0003723 ... P50579 9812898
    1869 1b6a:A (1.6) BS02 CO 3.4.11.18 GO:0003723 ... P50579 9812898
    1870 1b6a:A (1.6) BS03 TN4 3.4.11.18 GO:0003723 ... P50579 9812898 BindingDB: IC50=1nM, Ki=1nM
    1871 1b6h:A (1.8) BS01 peptide ? GO:0015031 ... P06202 10422831
    1872 1b6r:A (2.1) BS01 SO4 6.3.4.18 GO:0004638 ... P09029 10569930
    1873 1b6s:A (2.5) BS01 MG 6.3.4.18 GO:0004638 ... P09029 10569930
    1874 1b6s:A (2.5) BS02 ADP 6.3.4.18 GO:0004638 ... P09029 10569930
    1875 1b6s:B (2.5) BS01 MG 6.3.4.18 GO:0004638 ... P09029 10569930
    1876 1b6s:B (2.5) BS02 ADP 6.3.4.18 GO:0004638 ... P09029 10569930
    1877 1b6s:C (2.5) BS01 MG 6.3.4.18 GO:0004638 ... P09029 10569930
    1878 1b6s:C (2.5) BS02 ADP 6.3.4.18 GO:0004638 ... P09029 10569930
    1879 1b6s:D (2.5) BS01 MG 6.3.4.18 GO:0004638 ... P09029 10569930
    1880 1b6s:D (2.5) BS02 ADP 6.3.4.18 GO:0004638 ... P09029 10569930
    1881 1b6t:B (1.8) BS01 COD 2.7.7.3 GO:0003824 ... P0A6I6 10205156
    1882 1b6z:A (2.0) BS01 ZN 4.2.3.12 GO:0003874 ... P27213 10024455
    1883 1b6z:B (2.0) BS01 ZN 4.2.3.12 GO:0003874 ... P27213 10024455
    1884 1b70:A (2.7) BS01 PHE 6.1.1.20 GO:0000049 ... P27001 10092459
    1885 1b71:A (1.9) BS01 FE ? GO:0005506 ... P24931 10201393
    1886 1b71:A (1.9) BS02 FE ? GO:0005506 ... P24931 10201393
    1887 1b71:A (1.9) BS03 ZN ? GO:0005506 ... P24931 10201393
    1888 1b7a:A (2.25) BS01 OPE ? GO:0004867 ... P13696 9782057
    1889 1b7a:B (2.25) BS01 OPE ? GO:0004867 ... P13696 9782057
    1890 1b7b:A (2.8) BS01 SO4 2.7.2.2 GO:0005524 ... P0A2X8 10211841
    1891 1b7b:B (2.8) BS01 SO4 2.7.2.2 GO:0005524 ... P0A2X8 10211841
    1892 1b7b:C (2.8) BS01 SO4 2.7.2.2 GO:0005524 ... P0A2X8 10211841
    1893 1b7b:D (2.8) BS01 SO4 2.7.2.2 GO:0005524 ... P0A2X8 10211841
    1894 1b7f:A (2.6) BS01 rna ? GO:0003676 ... P19339 10217141
    1895 1b7f:B (2.6) BS01 rna ? GO:0003676 ... P19339 10217141
    1896 1b7h:A (2.0) BS01 peptide ? GO:0015031 ... P06202 10422831
    1897 1b7t:A (2.5) BS01 MG ? GO:0003774 ... P24733 10338210
    1898 1b7t:A (2.5) BS02 ADP ? GO:0003774 ... P24733 10338210
    1899 1b7t:Y (2.5) BS01 MG ? GO:0005509 ... P13543 10338210
    1900 1b7t:Z (2.5) BS01 CA ? GO:0005509 ... P07291 10338210
    1901 1b7v:A (1.7) BS01 HEC ? GO:0005506 ... P82599 11052663
    1902 1b7y:A (2.5) BS01 FYA 6.1.1.20 GO:0000049 ... P27001 10092459
    1903 1b7z:A (2.7) BS01 FE 3.4.21.- GO:0001503 ... O77811 10531474
    1904 1b7z:A (2.7) BS02 FE 3.4.21.- GO:0001503 ... O77811 10531474
    1905 1b7z:A (2.7) BS03 OXL 3.4.21.- GO:0001503 ... O77811 10531474
    1906 1b7z:A (2.7) BS04 OXL 3.4.21.- GO:0001503 ... O77811 10531474
    1907 1b86:A (2.5) BS01 HEM ? GO:0004601 ... P69905 8377203
    1908 1b86:B (2.5) BS01 HEM ? GO:0004601 ... P68871 8377203
    1909 1b86:B (2.5) BS02 DG2 ? GO:0004601 ... P68871 8377203
    1910 1b86:C (2.5) BS01 HEM ? GO:0004601 ... P69905 8377203
    1911 1b86:D (2.5) BS01 HEM ? GO:0004601 ... P68871 8377203
    1912 1b8a:A (1.9) BS01 MN 6.1.1.12 GO:0000166 ... Q52428 9724658
    1913 1b8a:A (1.9) BS02 ATP 6.1.1.12 GO:0000166 ... Q52428 9724658
    1914 1b8a:B (1.9) BS01 MN 6.1.1.12 GO:0000166 ... Q52428 9724658
    1915 1b8a:B (1.9) BS02 ATP 6.1.1.12 GO:0000166 ... Q52428 9724658
    1916 1b8c:A (2.0) BS01 MG ? GO:0005509 ... P02618 10545326
    1917 1b8c:B (2.0) BS01 MG ? GO:0005509 ... P02618 10545326
    1918 1b8d:A (1.9) BS01 PEB ? GO:0009507 ... O36005 10388620
    1919 1b8d:A (1.9) BS02 PEB ? GO:0009507 ... O36005 10388620
    1920 1b8d:A (1.9) BS03 PEB ? GO:0009507 ... O36005 10388620
    1921 1b8d:A (1.9) BS04 PEB ? GO:0009507 ... O36005 10388620
    1922 1b8d:B (1.9) BS01 PEB ? GO:0009507 ... O36004 10388620
    1923 1b8d:B (1.9) BS02 PEB ? GO:0009507 ... O36004 10388620
    1924 1b8d:B (1.9) BS03 PUB ? GO:0009507 ... O36004 10388620
    1925 1b8d:K (1.9) BS01 PEB ? GO:0009507 ... O36005 10388620
    1926 1b8d:K (1.9) BS02 PEB ? GO:0009507 ... O36005 10388620
    1927 1b8d:K (1.9) BS03 PEB ? GO:0009507 ... O36005 10388620
    1928 1b8d:L (1.9) BS01 PEB ? GO:0009507 ... O36004 10388620
    1929 1b8d:L (1.9) BS02 PEB ? GO:0009507 ... O36004 10388620
    1930 1b8d:L (1.9) BS03 PUB ? GO:0009507 ... O36004 10388620
    1931 1b8i:A (2.4) BS01 dna ? GO:0000981 ... P83949 10067897
    1932 1b8i:A (2.4) BS02 dna ? GO:0000981 ... P83949 10067897
    1933 1b8j:A (1.9) BS01 ZN 3.1.3.1 GO:0000287 ... P00634 10085061
    1934 1b8j:A (1.9) BS02 ZN 3.1.3.1 GO:0000287 ... P00634 10085061
    1935 1b8j:A (1.9) BS03 MG 3.1.3.1 GO:0000287 ... P00634 10085061
    1936 1b8j:B (1.9) BS01 ZN 3.1.3.1 GO:0000287 ... P00634 10085061
    1937 1b8j:B (1.9) BS02 ZN 3.1.3.1 GO:0000287 ... P00634 10085061
    1938 1b8j:B (1.9) BS03 MG 3.1.3.1 GO:0000287 ... P00634 10085061
    1939 1b8l:A (1.7) BS01 CA ? GO:0005509 ... P02618 10545326
    1940 1b8n:A (2.0) BS01 IMG 2.4.2.1 GO:0003824 ... P55859 12463747 MOAD: Ki=30pM
    PDBbind: -logKd/Ki=10.52, Ki=30pM
    BindingDB: Ki=0.030000nM
    1941 1b8o:A (1.5) BS01 PO4 2.4.2.1 GO:0003824 ... P55859 11170405
    1942 1b8o:A (1.5) BS02 IMH 2.4.2.1 GO:0003824 ... P55859 11170405 MOAD: Ki=23pM
    PDBbind: -logKd/Ki=10.64, Ki=23pM
    1943 1b8r:A (1.9) BS01 CA ? GO:0005509 ... P02618 10545326
    1944 1b8r:A (1.9) BS02 CA ? GO:0005509 ... P02618 10545326
    1945 1b8s:A (1.65) BS01 FAD 1.1.3.6
    5.3.3.1
    GO:0004769 ... P12676 10194345
    1946 1b8t:A (-1.00) BS01 ZN ? GO:0001725 ... P67966 10231520
    1947 1b8t:A (-1.00) BS02 ZN ? GO:0001725 ... P67966 10231520
    1948 1b8t:A (-1.00) BS03 ZN ? GO:0001725 ... P67966 10231520
    1949 1b8t:A (-1.00) BS04 ZN ? GO:0001725 ... P67966 10231520
    1950 1b8y:A (2.0) BS01 ZN 3.4.24.17 GO:0004222 ... P08254 10422833
    1951 1b8y:A (2.0) BS02 ZN 3.4.24.17 GO:0004222 ... P08254 10422833
    1952 1b8y:A (2.0) BS03 CA 3.4.24.17 GO:0004222 ... P08254 10422833
    1953 1b8y:A (2.0) BS04 CA 3.4.24.17 GO:0004222 ... P08254 10422833
    1954 1b8y:A (2.0) BS05 CA 3.4.24.17 GO:0004222 ... P08254 10422833
    1955 1b8y:A (2.0) BS06 IN7 3.4.24.17 GO:0004222 ... P08254 10422833 MOAD: Ki=14nM
    PDBbind: -logKd/Ki=7.85, Ki=14nM
    1956 1b93:B (1.9) BS01 PO4 4.2.3.3 GO:0005737 ... P0A731 10368300
    1957 1b99:A (2.7) BS01 FUP 2.7.4.6 GO:0004550 ... P22887 10353838
    1958 1b99:C (2.7) BS01 POP 2.7.4.6 GO:0004550 ... P22887 10353838
    1959 1b99:D (2.7) BS01 POP 2.7.4.6 GO:0004550 ... P22887 10353838
    1960 1b99:E (2.7) BS01 POP 2.7.4.6 GO:0004550 ... P22887 10353838
    1961 1b9a:A (2.0) BS01 CA ? GO:0005509 ... P02618 10545326
    1962 1b9a:A (2.0) BS02 CA ? GO:0005509 ... P02618 10545326
    1963 1b9e:B (2.5) BS01 peptide ? GO:0005179 ... P01308 10489447
    1964 1b9e:D (2.5) BS01 peptide ? GO:0005179 ... P01308 10489447
    1965 1b9j:A (1.8) BS01 peptide ? GO:0015031 ... P06202 10438628
    1966 1b9o:A (1.15) BS01 CA ? GO:0000139 ... P00709 10080897
    1967 1b9r:A (-1.00) BS01 FES ? GO:0005829 ... P33007 10220356
    1968 1b9s:A (2.5) BS01 CA 3.2.1.18 GO:0004308 ... P03474 10547289
    1969 1b9s:A (2.5) BS02 FDI 3.2.1.18 GO:0004308 ... P03474 10547289 MOAD: ic50>667uM
    PDBbind: -logKd/Ki=3.18, IC50>667uM
    BindingDB: IC50=670000nM
    1970 1b9t:A (2.4) BS01 CA 3.2.1.18 GO:0004308 ... P03474 10547289
    1971 1b9t:A (2.4) BS02 RAI 3.2.1.18 GO:0004308 ... P03474 10547289 MOAD: ic50=8uM
    PDBbind: -logKd/Ki=5.10, IC50=8uM
    BindingDB: IC50=8000nM
    1972 1b9v:A (2.35) BS01 CA 3.2.1.18 GO:0004308 ... P03474 10547289
    1973 1b9v:A (2.35) BS02 RA2 3.2.1.18 GO:0004308 ... P03474 10547289 MOAD: ic50=224uM
    PDBbind: -logKd/Ki=3.65, IC50=224uM
    BindingDB: IC50=271000nM
    1974 1ba3:A (2.2) BS01 MBR 1.13.12.7 GO:0001676 ... P08659 9788915
    1975 1ba3:A (2.2) BS02 MBR 1.13.12.7 GO:0001676 ... P08659 9788915
    1976 1ba9:A (-1.00) BS01 ZN 1.15.1.1 GO:0000302 ... P00441 9718300
    1977 1ba9:A (-1.00) BS02 CU1 1.15.1.1 GO:0000302 ... P00441 9718300
    1978 1bab:A (1.5) BS01 HEM ? GO:0004601 ... P69905 1618774
    1979 1bab:B (1.5) BS01 HEM ? GO:0004601 ... P68871 1618774
    1980 1bab:C (1.5) BS01 HEM ? GO:0004601 ... P69905 1618774
    1981 1bab:D (1.5) BS01 HEM ? GO:0004601 ... P68871 1618774
    1982 1bap:A (1.75) BS01 ARA ? GO:0015407 ... P02924 2204627 MOAD: Kd=0.14uM
    1983 1bap:A (1.75) BS02 ARB ? GO:0015407 ... P02924 2204627 MOAD: Kd=0.14uM
    PDBbind: -logKd/Ki=6.85, Kd=0.14uM
    1984 1baw:A (2.8) BS01 CU ? GO:0005507 ... Q51883 10089349
    1985 1baw:A (2.8) BS02 ZN ? GO:0005507 ... Q51883 10089349
    1986 1baw:B (2.8) BS01 CU ? GO:0005507 ... Q51883 10089349
    1987 1baw:B (2.8) BS02 ZN ? GO:0005507 ... Q51883 10089349
    1988 1baw:C (2.8) BS01 CU ? GO:0005507 ... Q51883 10089349
    1989 1baw:C (2.8) BS02 ZN ? GO:0005507 ... Q51883 10089349
    1990 1bb6:A (2.0) BS01 UMG 3.2.1.17 GO:0003796 ... P11941 10089395 MOAD: Ka=500000M^-1
    1991 1bb7:A (2.0) BS01 GUM 3.2.1.17 GO:0003796 ... P11941 10089395 MOAD: Ka=15000M^-1
    1992 1bbb:A (1.7) BS01 HEM ? GO:0004601 ... P69905 1512262
    1993 1bbb:B (1.7) BS01 HEM ? GO:0004601 ... P68871 1512262
    1994 1bbb:C (1.7) BS01 HEM ? GO:0004601 ... P69905 1512262
    1995 1bbb:D (1.7) BS01 HEM ? GO:0004601 ... P68871 1512262
    1996 1bbh:A (1.8) BS01 HEC ? GO:0005506 ... P00154 8230224
    1997 1bbh:B (1.8) BS01 HEC ? GO:0005506 ... P00154 8230224
    1998 1bbp:A (2.0) BS01 BLV ? GO:0000302 ... P09464 3430616
    1999 1bbp:B (2.0) BS01 BLV ? GO:0000302 ... P09464 3430616
    2000 1bbp:C (2.0) BS01 BLV ? GO:0000302 ... P09464 3430616

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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