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BioLiP
Download all results in tab-seperated text for 817662 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    19201 1i48:B (3.25) BS03 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19202 1i48:C (3.25) BS01 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19203 1i48:C (3.25) BS02 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19204 1i48:C (3.25) BS03 CCO 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531 PDBbind: -logKd/Ki=5.70, Ki=2.0uM
    19205 1i48:D (3.25) BS01 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19206 1i48:D (3.25) BS02 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19207 1i48:D (3.25) BS03 CCO 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19208 1i48:E (3.25) BS01 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19209 1i48:E (3.25) BS02 CCO 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19210 1i48:E (3.25) BS03 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19211 1i48:F (3.25) BS01 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19212 1i48:F (3.25) BS02 CCO 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19213 1i48:F (3.25) BS03 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19214 1i48:G (3.25) BS01 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19215 1i48:G (3.25) BS02 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19216 1i48:G (3.25) BS03 CCO 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19217 1i48:H (3.25) BS01 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19218 1i48:H (3.25) BS02 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19219 1i48:H (3.25) BS03 CCO 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19220 1i48:I (3.25) BS01 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19221 1i48:I (3.25) BS02 CCO 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19222 1i48:I (3.25) BS03 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19223 1i48:J (3.25) BS01 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19224 1i48:J (3.25) BS02 CCO 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19225 1i48:J (3.25) BS03 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19226 1i48:K (3.25) BS01 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19227 1i48:K (3.25) BS02 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19228 1i48:K (3.25) BS03 CCO 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19229 1i48:L (3.25) BS01 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19230 1i48:L (3.25) BS02 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19231 1i48:L (3.25) BS03 CCO 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    19232 1i4a:A (2.0) BS01 CA ? GO:0001786 ... P13214 11300800
    19233 1i4a:A (2.0) BS02 CA ? GO:0001786 ... P13214 11300800
    19234 1i4d:D (2.5) BS01 GDP 3.6.5.2 GO:0001764 ... P63000 11346801 MOAD: Kd=3uM
    19235 1i4g:A (2.1) BS01 ZN ? GO:0005515 ... P0A0L2 11713682
    19236 1i4h:A (2.9) BS01 ZN ? GO:0005515 ... P0A0L2 11713682
    19237 1i4h:B (2.9) BS01 ZN ? GO:0005515 ... P0A0L2 11713682
    19238 1i4l:D (2.7) BS01 GDP 3.6.5.2 GO:0001764 ... P63000 11346801
    19239 1i4o:A (2.4) BS01 peptide 3.4.22.60 GO:0003723 ... P55210 11257231
    19240 1i4o:B (2.4) BS01 peptide 3.4.22.60 GO:0003723 ... P55210 11257231
    19241 1i4p:A (2.0) BS01 ZN ? GO:0005576 ... P34071 11526318
    19242 1i4q:A (2.2) BS01 ZN ? GO:0005576 ... P34071 11526318
    19243 1i4r:A (2.1) BS01 ZN ? GO:0005576 ... P34071 11526318
    19244 1i4t:D (2.6) BS01 GNP 3.6.5.2 GO:0001764 ... P63000 11346801
    19245 1i4x:A (2.4) BS01 ZN ? GO:0005576 ... P34071 11526318
    19246 1i4y:A (1.8) BS01 FEO ? GO:0005344 ... P02244 11372200
    19247 1i4y:B (1.8) BS01 FEO ? GO:0005344 ... P02244 11372200
    19248 1i4y:C (1.8) BS01 FEO ? GO:0005344 ... P02244 11372200
    19249 1i4y:D (1.8) BS01 FEO ? GO:0005344 ... P02244 11372200
    19250 1i4y:E (1.8) BS01 FEO ? GO:0005344 ... P02244 11372200
    19251 1i4y:F (1.8) BS01 FEO ? GO:0005344 ... P02244 11372200
    19252 1i4y:G (1.8) BS01 FEO ? GO:0005344 ... P02244 11372200
    19253 1i4y:H (1.8) BS01 FEO ? GO:0005344 ... P02244 11372200
    19254 1i4z:A (2.1) BS01 FEO ? GO:0005344 ... P02244 11372200
    19255 1i4z:B (2.1) BS01 FEO ? GO:0005344 ... P02244 11372200
    19256 1i4z:C (2.1) BS01 FEO ? GO:0005344 ... P02244 11372200
    19257 1i4z:D (2.1) BS01 FEO ? GO:0005344 ... P02244 11372200
    19258 1i4z:E (2.1) BS01 FEO ? GO:0005344 ... P02244 11372200
    19259 1i4z:F (2.1) BS01 FEO ? GO:0005344 ... P02244 11372200
    19260 1i4z:G (2.1) BS01 FEO ? GO:0005344 ... P02244 11372200
    19261 1i4z:H (2.1) BS01 FEO ? GO:0005344 ... P02244 11372200
    19262 1i50:A (2.8) BS01 ZN 2.7.7.6 GO:0000428 ... P04050 11313498
    19263 1i50:A (2.8) BS02 ZN 2.7.7.6 GO:0000428 ... P04050 11313498
    19264 1i50:A (2.8) BS03 MN 2.7.7.6 GO:0000428 ... P04050 11313498
    19265 1i50:B (2.8) BS01 ZN 2.7.7.6 GO:0000428 ... P08518 11313498
    19266 1i50:C (2.8) BS01 ZN 2.7.7.6 GO:0000428 ... P16370 11313498
    19267 1i50:I (2.8) BS01 ZN 2.7.7.6 GO:0000428 ... P27999 11313498
    19268 1i50:I (2.8) BS02 ZN 2.7.7.6 GO:0000428 ... P27999 11313498
    19269 1i50:J (2.8) BS01 ZN 2.7.7.6 GO:0000428 ... P22139 11313498
    19270 1i50:L (2.8) BS01 ZN 2.7.7.6 GO:0000428 ... P40422 11313498
    19271 1i51:A (2.45) BS01 peptide 3.4.22.60 GO:0004197 ... P55210 11257230
    19272 1i51:B (2.45) BS01 peptide 3.4.22.60 GO:0004197 ... P55210 11257230
    19273 1i51:C (2.45) BS01 peptide 3.4.22.60 GO:0004197 ... P55210 11257230
    19274 1i51:D (2.45) BS01 peptide 3.4.22.60 GO:0004197 ... P55210 11257230
    19275 1i52:A (1.5) BS01 CTP 2.7.7.60 GO:0000287 ... Q46893 11427897
    19276 1i53:A (1.8) BS01 CU ? GO:0005507 ... P00282 11457048
    19277 1i53:B (1.8) BS01 CU ? GO:0005507 ... P00282 11457048
    19278 1i54:A (1.5) BS01 HEC ? GO:0005739 ... P81459 11296248
    19279 1i54:A (1.5) BS02 ZNH ? GO:0005739 ... P81459 11296248
    19280 1i54:B (1.5) BS01 HEC ? GO:0005739 ... P81459 11296248
    19281 1i54:B (1.5) BS02 ZNH ? GO:0005739 ... P81459 11296248
    19282 1i55:A (2.0) BS01 HEC ? GO:0005739 ... P81459 11296248
    19283 1i55:A (2.0) BS02 ZNH ? GO:0005739 ... P81459 11296248
    19284 1i55:B (2.0) BS01 HEC ? GO:0005739 ... P81459 11296248
    19285 1i55:B (2.0) BS02 ZNH ? GO:0005739 ... P81459 11296248
    19286 1i58:A (1.6) BS01 ACP 2.7.13.3 GO:0016310 ... Q56310 11276258
    19287 1i58:B (1.6) BS01 ADP 2.7.13.3 GO:0016310 ... Q56310 11276258
    19288 1i59:A (1.8) BS01 ANP 2.7.13.3 GO:0016310 ... Q56310 11276258
    19289 1i59:B (1.8) BS01 ADP 2.7.13.3 GO:0016310 ... Q56310 11276258
    19290 1i5a:A (1.9) BS01 MN 2.7.13.3 GO:0016310 ... Q56310 11276258
    19291 1i5a:A (1.9) BS02 ACP 2.7.13.3 GO:0016310 ... Q56310 11276258
    19292 1i5a:B (1.9) BS01 MN 2.7.13.3 GO:0016310 ... Q56310 11276258
    19293 1i5a:B (1.9) BS02 ACP 2.7.13.3 GO:0016310 ... Q56310 11276258
    19294 1i5b:A (1.94) BS01 MN 2.7.13.3 GO:0016310 ... Q56310 11276258
    19295 1i5b:A (1.94) BS02 ANP 2.7.13.3 GO:0016310 ... Q56310 11276258
    19296 1i5b:B (1.94) BS01 MN 2.7.13.3 GO:0016310 ... Q56310 11276258
    19297 1i5b:B (1.94) BS02 ANP 2.7.13.3 GO:0016310 ... Q56310 11276258
    19298 1i5c:A (1.9) BS01 ADP 2.7.13.3 GO:0016310 ... Q56310 11276258
    19299 1i5c:B (1.9) BS01 ADP 2.7.13.3 GO:0016310 ... Q56310 11276258
    19300 1i5d:A (2.9) BS01 128 2.7.13.3 GO:0016310 ... Q56310 11276258 PDBbind: -logKd/Ki=8.00, Kd<0.010uM
    19301 1i5e:A (3.0) BS01 U5P 2.4.2.9 GO:0000287 ... P70881 12037295
    19302 1i5e:B (3.0) BS01 U5P 2.4.2.9 GO:0000287 ... P70881 12037295
    19303 1i5g:A (1.4) BS01 TS5 1.8.1.8 GO:0004791 ... O77093 11347894
    19304 1i5l:A (2.75) BS01 URI ? GO:0003723 ... O29386 11331594
    19305 1i5l:B (2.75) BS01 URI ? GO:0003723 ... O29386 11331594
    19306 1i5l:B (2.75) BS02 URI ? GO:0003723 ... O29386 11331594
    19307 1i5l:C (2.75) BS01 URI ? GO:0003723 ... O29386 11331594
    19308 1i5l:E (2.75) BS01 rna ? GO:0003723 ... O29386 11331594
    19309 1i5l:F (2.75) BS01 rna ? GO:0003723 ... O29386 11331594
    19310 1i5l:G (2.75) BS01 rna ? GO:0003723 ... O29386 11331594
    19311 1i5l:G (2.75) BS02 URI ? GO:0003723 ... O29386 11331594
    19312 1i5l:H (2.75) BS01 URI ? GO:0003723 ... O29386 11331594
    19313 1i5l:J (2.75) BS01 rna ? GO:0003723 ... O29386 11331594
    19314 1i5l:K (2.75) BS01 rna ? GO:0003723 ... O29386 11331594
    19315 1i5l:L (2.75) BS01 rna ? GO:0003723 ... O29386 11331594
    19316 1i5o:B (2.8) BS01 ZN ? GO:0005515 ... P0A7F3 11323717
    19317 1i5o:B (2.8) BS02 PAL ? GO:0005515 ... P0A7F3 11323717
    19318 1i5o:D (2.8) BS01 ZN ? GO:0005515 ... P0A7F3 11323717
    19319 1i5q:A (1.83) BS01 MOX 3.5.2.6 GO:0008800 ... P00811 11434768
    19320 1i5q:B (1.83) BS01 MOX 3.5.2.6 GO:0008800 ... P00811 11434768
    19321 1i5r:A (1.6) BS01 HYC 1.1.1.51
    1.1.1.62
    GO:0003824 ... P14061 12223444 MOAD: Ki=3nM
    PDBbind: -logKd/Ki=8.52, Ki=3.0nM
    BindingDB: IC50=52nM, Ki=3nM
    19322 1i5s:A (2.2) BS01 ADP ? GO:0003777 ... P33173 11373668
    19323 1i5t:A (-1.00) BS01 HEC ? GO:0005515 ... P00004 11941512
    19324 1i5u:A (-1.00) BS01 HEM ? GO:0020037 ... P00171 11714912
    19325 1i5z:A (1.9) BS01 CMP ? GO:0003677 ... P0ACJ8 N/A
    19326 1i5z:A (1.9) BS02 CMP ? GO:0003677 ... P0ACJ8 N/A
    19327 1i5z:B (1.9) BS01 CMP ? GO:0003677 ... P0ACJ8 N/A
    19328 1i6d:A (-1.00) BS01 HEC ? GO:0009055 ... P54820 11591150
    19329 1i6e:A (-1.00) BS01 HEC ? GO:0009055 ... P54820 11591150
    19330 1i6h:A (3.3) BS01 dna 2.7.7.6 GO:0000428 ... P04050 11313499
    19331 1i6h:A (3.3) BS02 rna 2.7.7.6 GO:0000428 ... P04050 11313499
    19332 1i6h:A (3.3) BS03 MG 2.7.7.6 GO:0000428 ... P04050 11313499
    19333 1i6h:A (3.3) BS04 ZN 2.7.7.6 GO:0000428 ... P04050 11313499
    19334 1i6h:B (3.3) BS01 dna 2.7.7.6 GO:0000428 ... P08518 11313499
    19335 1i6h:B (3.3) BS02 rna 2.7.7.6 GO:0000428 ... P08518 11313499
    19336 1i6h:B (3.3) BS03 ZN 2.7.7.6 GO:0000428 ... P08518 11313499
    19337 1i6h:C (3.3) BS01 ZN 2.7.7.6 GO:0000428 ... P16370 11313499
    19338 1i6h:I (3.3) BS01 ZN 2.7.7.6 GO:0000428 ... P27999 11313499
    19339 1i6h:I (3.3) BS02 ZN 2.7.7.6 GO:0000428 ... P27999 11313499
    19340 1i6h:J (3.3) BS01 ZN 2.7.7.6 GO:0000428 ... P22139 11313499
    19341 1i6h:L (3.3) BS01 ZN 2.7.7.6 GO:0000428 ... P40422 11313499
    19342 1i6i:A (2.0) BS01 ACP ? GO:0003777 ... P33173 11373668
    19343 1i6k:A (1.72) BS01 TYM 6.1.1.2 GO:0000166 ... P00953 11679724
    19344 1i6l:A (1.72) BS01 TYM 6.1.1.2 GO:0000166 ... P00953 11679724
    19345 1i6m:A (1.72) BS01 TYM 6.1.1.2 GO:0000166 ... P00953 11679724
    19346 1i6n:A (1.8) BS01 ZN 5.3.99.11 GO:0016853 ... P42419 12112707
    19347 1i6o:A (2.2) BS01 ZN 4.2.1.1 GO:0004089 ... P61517 11316870
    19348 1i6o:B (2.2) BS01 ZN 4.2.1.1 GO:0004089 ... P61517 11316870
    19349 1i6p:A (2.0) BS01 ZN 4.2.1.1 GO:0004089 ... P61517 11316870
    19350 1i6q:A (2.7) BS01 FE 3.4.21.- GO:0001503 ... Q9TUM0 11473113
    19351 1i6q:A (2.7) BS02 FE 3.4.21.- GO:0001503 ... Q9TUM0 11473113
    19352 1i6t:A (1.2) BS01 CA 3.6.1.1 GO:0000287 ... P0A7A9 11846572
    19353 1i6t:A (1.2) BS02 CA 3.6.1.1 GO:0000287 ... P0A7A9 11846572
    19354 1i6t:A (1.2) BS03 POP 3.6.1.1 GO:0000287 ... P0A7A9 11846572
    19355 1i6u:A (2.6) BS01 rna ? GO:0003735 ... P54041 11478863
    19356 1i6u:B (2.6) BS01 rna ? GO:0003735 ... P54041 11478863
    19357 1i6u:B (2.6) BS02 rna ? GO:0003735 ... P54041 11478863
    19358 1i6v:C (3.3) BS01 RFP 2.7.7.6 GO:0000428 ... Q9KWU7 11290327 PDBbind: -logKd/Ki=5.00, Ki=10uM
    19359 1i6v:D (3.3) BS01 MG 2.7.7.6 GO:0003677 ... Q9KWU6 11290327
    19360 1i6v:D (3.3) BS02 ZN 2.7.7.6 GO:0003677 ... Q9KWU6 11290327
    19361 1i6x:A (2.2) BS01 CMP ? GO:0003677 ... P0ACJ8 N/A
    19362 1i6x:A (2.2) BS02 CMP ? GO:0003677 ... P0ACJ8 N/A
    19363 1i6x:B (2.2) BS01 CMP ? GO:0003677 ... P0ACJ8 N/A
    19364 1i72:A (2.0) BS01 MAO 4.1.1.50 GO:0004014 ... P17707 11583147 PDBbind: -logKd/Ki=7.26, IC50=55nM
    BindingDB: IC50=55nM
    19365 1i72:A (2.0) BS02 PUT 4.1.1.50 GO:0004014 ... P17707 11583147
    19366 1i72:B (2.0) BS01 MAO 4.1.1.50 GO:0004014 ... P17707 11583147 PDBbind: -logKd/Ki=7.26, IC50=55nM
    BindingDB: IC50=55nM
    19367 1i73:A (1.4) BS01 peptide 3.4.24.34 GO:0004222 ... P22894 10978185
    19368 1i73:A (1.4) BS02 CA 3.4.24.34 GO:0004222 ... P22894 10978185
    19369 1i73:A (1.4) BS03 CA 3.4.24.34 GO:0004222 ... P22894 10978185
    19370 1i73:A (1.4) BS04 ZN 3.4.24.34 GO:0004222 ... P22894 10978185
    19371 1i73:A (1.4) BS05 ZN 3.4.24.34 GO:0004222 ... P22894 10978185
    19372 1i74:A (2.2) BS01 MN 3.6.1.1 GO:0004427 ... O68579 11525166
    19373 1i74:A (2.2) BS02 MN 3.6.1.1 GO:0004427 ... O68579 11525166
    19374 1i74:A (2.2) BS03 SO4 3.6.1.1 GO:0004427 ... O68579 11525166
    19375 1i74:A (2.2) BS04 SO4 3.6.1.1 GO:0004427 ... O68579 11525166
    19376 1i74:B (2.2) BS01 MN 3.6.1.1 GO:0004427 ... O68579 11525166
    19377 1i74:B (2.2) BS02 MN 3.6.1.1 GO:0004427 ... O68579 11525166
    19378 1i74:B (2.2) BS03 SO4 3.6.1.1 GO:0004427 ... O68579 11525166
    19379 1i75:A (2.0) BS01 CA 2.4.1.19 GO:0003824 ... P05618 11275559
    19380 1i75:A (2.0) BS02 CA 2.4.1.19 GO:0003824 ... P05618 11275559
    19381 1i75:A (2.0) BS03 NOJ 2.4.1.19 GO:0003824 ... P05618 11275559
    19382 1i75:A (2.0) BS04 NOJ 2.4.1.19 GO:0003824 ... P05618 11275559
    19383 1i75:B (2.0) BS01 CA 2.4.1.19 GO:0003824 ... P05618 11275559
    19384 1i75:B (2.0) BS02 CA 2.4.1.19 GO:0003824 ... P05618 11275559
    19385 1i75:B (2.0) BS03 NOJ 2.4.1.19 GO:0003824 ... P05618 11275559
    19386 1i75:B (2.0) BS04 NOJ 2.4.1.19 GO:0003824 ... P05618 11275559
    19387 1i76:A (1.2) BS01 CA 3.4.24.34 GO:0004222 ... P22894 10978185
    19388 1i76:A (1.2) BS02 CA 3.4.24.34 GO:0004222 ... P22894 10978185
    19389 1i76:A (1.2) BS03 ZN 3.4.24.34 GO:0004222 ... P22894 10978185
    19390 1i76:A (1.2) BS04 ZN 3.4.24.34 GO:0004222 ... P22894 10978185
    19391 1i76:A (1.2) BS05 BSI 3.4.24.34 GO:0004222 ... P22894 10978185
    19392 1i77:A (1.95) BS01 HEM ? GO:0009055 ... Q9L915 11358521
    19393 1i77:A (1.95) BS02 HEM ? GO:0009055 ... Q9L915 11358521
    19394 1i77:A (1.95) BS03 HEM ? GO:0009055 ... Q9L915 11358521
    19395 1i77:A (1.95) BS04 HEM ? GO:0009055 ... Q9L915 11358521
    19396 1i79:A (2.01) BS01 MHZ 4.1.1.50 GO:0004014 ... P17707 11583147
    19397 1i79:A (2.01) BS02 PUT 4.1.1.50 GO:0004014 ... P17707 11583147
    19398 1i79:B (2.01) BS01 MHZ 4.1.1.50 GO:0004014 ... P17707 11583147
    19399 1i7a:A (2.24) BS01 peptide ? GO:0007216 ... Q9QWW1 11491285
    19400 1i7a:B (2.24) BS01 peptide ? GO:0007216 ... Q9QWW1 11491285

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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