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BioLiP
Download all results in tab-seperated text for 832530 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    21401 1is7:P (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    21402 1is7:P (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    21403 1is7:Q (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    21404 1is7:Q (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    21405 1is7:R (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    21406 1is7:R (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    21407 1is7:S (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    21408 1is7:S (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    21409 1is7:T (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    21410 1is7:T (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    21411 1is8:A (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    21412 1is8:B (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    21413 1is8:C (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    21414 1is8:D (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    21415 1is8:E (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    21416 1is8:F (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    21417 1is8:G (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    21418 1is8:H (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    21419 1is8:I (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    21420 1is8:J (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    21421 1is8:K (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    21422 1is8:K (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    21423 1is8:L (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    21424 1is8:L (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    21425 1is8:M (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    21426 1is8:M (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    21427 1is8:N (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    21428 1is8:N (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    21429 1is8:O (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    21430 1is8:O (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    21431 1is8:P (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    21432 1is8:P (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    21433 1is8:Q (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    21434 1is8:Q (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    21435 1is8:R (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    21436 1is8:R (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    21437 1is8:S (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    21438 1is8:S (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    21439 1is8:T (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    21440 1is8:T (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    21441 1isa:A (1.8) BS01 FE2 1.15.1.1 GO:0000303 ... P0AGD3 7849024
    21442 1isa:B (1.8) BS01 FE2 1.15.1.1 GO:0000303 ... P0AGD3 7849024
    21443 1isb:A (1.85) BS01 FE 1.15.1.1 GO:0000303 ... P0AGD3 7849024
    21444 1isb:B (1.85) BS01 FE 1.15.1.1 GO:0000303 ... P0AGD3 7849024
    21445 1isc:A (1.8) BS01 FE 1.15.1.1 GO:0000303 ... P0AGD3 7849024
    21446 1isc:A (1.8) BS02 AZI 1.15.1.1 GO:0000303 ... P0AGD3 7849024
    21447 1isc:B (1.8) BS01 FE 1.15.1.1 GO:0000303 ... P0AGD3 7849024
    21448 1isc:B (1.8) BS02 AZI 1.15.1.1 GO:0000303 ... P0AGD3 7849024
    21449 1isg:A (2.6) BS01 AGS 3.2.2.6 GO:0001931 ... Q10588 11866528
    21450 1isg:B (2.6) BS01 AGS 3.2.2.6 GO:0001931 ... Q10588 11866528
    21451 1ish:A (2.4) BS01 ENP 3.2.2.6 GO:0001931 ... Q10588 11866528
    21452 1ish:B (2.4) BS01 ENP 3.2.2.6 GO:0001931 ... Q10588 11866528
    21453 1isi:A (2.1) BS01 NCA 3.2.2.6 GO:0001931 ... Q10588 11866528
    21454 1isi:A (2.1) BS02 ENQ 3.2.2.6 GO:0001931 ... Q10588 11866528
    21455 1isi:B (2.1) BS01 NCA 3.2.2.6 GO:0001931 ... Q10588 11866528
    21456 1isi:B (2.1) BS02 ENQ 3.2.2.6 GO:0001931 ... Q10588 11866528
    21457 1isj:A (2.3) BS01 NMN 3.2.2.6 GO:0001931 ... Q10588 11866528
    21458 1isj:B (2.3) BS01 NMN 3.2.2.6 GO:0001931 ... Q10588 11866528
    21459 1ism:A (3.0) BS01 NCA 3.2.2.6 GO:0001931 ... Q10588 11866528
    21460 1ism:B (3.0) BS01 NCA 3.2.2.6 GO:0001931 ... Q10588 11866528
    21461 1iso:A (1.9) BS01 NAD 1.1.1.42 GO:0000287 ... P08200 8639526
    21462 1isp:A (1.3) BS01 GOL 3.1.1.3 GO:0004806 ... P37957 12077437
    21463 1isq:A (2.3) BS01 peptide ? GO:0003677 ... O73947 12296822
    21464 1isr:A (4.0) BS01 GLU ? GO:0004930 ... P23385 11867751
    21465 1iss:A (3.3) BS01 MCG ? GO:0004930 ... P23385 11867751 BindingDB: Ki=>10000nM
    21466 1iss:B (3.3) BS01 MCG ? GO:0004930 ... P23385 11867751 BindingDB: Ki=>10000nM
    21467 1isu:A (1.5) BS01 SF4 ? GO:0009055 ... P33678 1453470
    21468 1isu:B (1.5) BS01 SF4 ? GO:0009055 ... P33678 1453470
    21469 1isv:A (2.1) BS01 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21470 1isv:A (2.1) BS02 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21471 1isv:A (2.1) BS03 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21472 1isv:B (2.1) BS01 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21473 1isv:B (2.1) BS02 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21474 1isv:B (2.1) BS03 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21475 1isw:A (2.1) BS01 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21476 1isw:A (2.1) BS02 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21477 1isw:A (2.1) BS03 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21478 1isw:A (2.1) BS04 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21479 1isw:A (2.1) BS05 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21480 1isw:B (2.1) BS01 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21481 1isw:B (2.1) BS02 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21482 1isw:B (2.1) BS03 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21483 1isw:B (2.1) BS04 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21484 1isw:B (2.1) BS05 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21485 1isw:B (2.1) BS06 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21486 1isx:A (2.1) BS01 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21487 1isx:A (2.1) BS02 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21488 1isx:A (2.1) BS03 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21489 1isx:A (2.1) BS04 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21490 1isx:A (2.1) BS05 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21491 1isx:A (2.1) BS06 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21492 1isx:B (2.1) BS01 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21493 1isx:B (2.1) BS02 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21494 1isx:B (2.1) BS03 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21495 1isx:B (2.1) BS04 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21496 1isx:B (2.1) BS05 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21497 1isx:B (2.1) BS06 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21498 1isx:B (2.1) BS07 XYP 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21499 1isy:A (2.1) BS01 BGC 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21500 1isy:A (2.1) BS02 BGC 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21501 1isy:B (2.1) BS01 BGC 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21502 1isy:B (2.1) BS02 BGC 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21503 1isz:A (2.0) BS01 GAL 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21504 1isz:A (2.0) BS02 GAL 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21505 1isz:B (2.0) BS01 GAL 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21506 1isz:B (2.0) BS02 GAL 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21507 1it0:A (2.0) BS01 GAL 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21508 1it0:A (2.0) BS02 GAL 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21509 1it0:B (2.0) BS01 GAL 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21510 1it0:B (2.0) BS02 GAL 3.2.1.8 GO:0000272 ... Q7SI98 11829503
    21511 1it1:A (-1.00) BS01 HEC ? GO:0009055 ... P00132 12054869
    21512 1it1:A (-1.00) BS02 HEC ? GO:0009055 ... P00132 12054869
    21513 1it1:A (-1.00) BS03 HEC ? GO:0009055 ... P00132 12054869
    21514 1it1:A (-1.00) BS04 HEC ? GO:0009055 ... P00132 12054869
    21515 1it2:A (1.6) BS01 HEM ? GO:0005344 ... Q7SID0 11923284
    21516 1it2:B (1.6) BS01 HEM ? GO:0005344 ... Q7SID0 11923284
    21517 1it3:A (2.1) BS01 HEM ? GO:0005344 ... Q7SID0 11923284
    21518 1it3:B (2.1) BS01 HEM ? GO:0005344 ... Q7SID0 11923284
    21519 1it3:C (2.1) BS01 HEM ? GO:0005344 ... Q7SID0 11923284
    21520 1it3:D (2.1) BS01 HEM ? GO:0005344 ... Q7SID0 11923284
    21521 1it4:A (-1.00) BS01 CA 3.1.1.4 GO:0004623 ... Q6UV28 11897786
    21522 1it6:A (2.0) BS01 MN 3.1.3.16 GO:0000070 ... P36873 12015153
    21523 1it6:A (2.0) BS02 MN 3.1.3.16 GO:0000070 ... P36873 12015153
    21524 1it6:A (2.0) BS03 CYU 3.1.3.16 GO:0000070 ... P36873 12015153 MOAD: Ki=4.1nM
    PDBbind: -logKd/Ki=8.39, Ki=4.1nM
    21525 1it6:B (2.0) BS01 MN 3.1.3.16 GO:0000070 ... P36873 12015153
    21526 1it6:B (2.0) BS02 MN 3.1.3.16 GO:0000070 ... P36873 12015153
    21527 1it6:B (2.0) BS03 CYU 3.1.3.16 GO:0000070 ... P36873 12015153 MOAD: Ki=4.1nM
    21528 1it7:A (2.3) BS01 ZN 2.4.2.48 GO:0002099 ... O58843 12054814
    21529 1it7:A (2.3) BS02 MG 2.4.2.48 GO:0002099 ... O58843 12054814
    21530 1it7:A (2.3) BS03 GUN 2.4.2.48 GO:0002099 ... O58843 12054814
    21531 1it7:B (2.3) BS01 ZN 2.4.2.48 GO:0002099 ... O58843 12054814
    21532 1it7:B (2.3) BS02 MG 2.4.2.48 GO:0002099 ... O58843 12054814
    21533 1it8:A (2.5) BS01 ZN 2.4.2.48 GO:0002099 ... O58843 12054814
    21534 1it8:A (2.5) BS02 MG 2.4.2.48 GO:0002099 ... O58843 12054814
    21535 1it8:A (2.5) BS03 PQ0 2.4.2.48 GO:0002099 ... O58843 12054814
    21536 1it8:B (2.5) BS01 ZN 2.4.2.48 GO:0002099 ... O58843 12054814
    21537 1it8:B (2.5) BS02 MG 2.4.2.48 GO:0002099 ... O58843 12054814
    21538 1itc:A (2.1) BS01 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    21539 1itc:A (2.1) BS02 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    21540 1itc:A (2.1) BS03 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    21541 1itc:A (2.1) BS04 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    21542 1itc:A (2.1) BS05 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    21543 1itc:A (2.1) BS06 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    21544 1itc:A (2.1) BS07 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    21545 1itc:A (2.1) BS08 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    21546 1itc:A (2.1) BS09 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    21547 1itc:A (2.1) BS10 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    21548 1itc:A (2.1) BS11 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    21549 1itc:A (2.1) BS12 GLC 3.2.1.2 GO:0000272 ... P36924 12741813
    21550 1itc:A (2.1) BS13 CA 3.2.1.2 GO:0000272 ... P36924 12741813
    21551 1ith:A (2.5) BS01 HEM ? GO:0005344 ... P06148 1515107
    21552 1ith:B (2.5) BS01 HEM ? GO:0005344 ... P06148 1515107
    21553 1itk:A (2.0) BS01 HEM 1.11.1.21 GO:0004096 ... O59651 12172540
    21554 1itk:B (2.0) BS01 HEM 1.11.1.21 GO:0004096 ... O59651 12172540
    21555 1ito:A (2.286) BS01 E6C 3.4.22.1 GO:0006508 ... P07688 12044902
    21556 1itq:A (2.3) BS01 ZN 3.4.13.19
    3.5.2.6
    GO:0005515 ... P16444 12144777
    21557 1itq:A (2.3) BS02 ZN 3.4.13.19
    3.5.2.6
    GO:0005515 ... P16444 12144777
    21558 1itq:B (2.3) BS01 ZN 3.4.13.19
    3.5.2.6
    GO:0005515 ... P16444 12144777
    21559 1itq:B (2.3) BS02 ZN 3.4.13.19
    3.5.2.6
    GO:0005515 ... P16444 12144777
    21560 1itu:A (2.0) BS01 ZN 3.4.13.19
    3.5.2.6
    GO:0005515 ... P16444 12144777
    21561 1itu:A (2.0) BS02 ZN 3.4.13.19
    3.5.2.6
    GO:0005515 ... P16444 12144777
    21562 1itu:A (2.0) BS03 CIL 3.4.13.19
    3.5.2.6
    GO:0005515 ... P16444 12144777
    21563 1itu:B (2.0) BS01 ZN 3.4.13.19
    3.5.2.6
    GO:0005515 ... P16444 12144777
    21564 1itu:B (2.0) BS02 ZN 3.4.13.19
    3.5.2.6
    GO:0005515 ... P16444 12144777
    21565 1itu:B (2.0) BS03 CIL 3.4.13.19
    3.5.2.6
    GO:0005515 ... P16444 12144777
    21566 1itw:A (1.95) BS01 MN 1.1.1.42 GO:0004450 ... P16100 12467571
    21567 1itw:B (1.95) BS01 MN 1.1.1.42 GO:0004450 ... P16100 12467571
    21568 1itw:C (1.95) BS01 MN 1.1.1.42 GO:0004450 ... P16100 12467571
    21569 1itw:D (1.95) BS01 MN 1.1.1.42 GO:0004450 ... P16100 12467571
    21570 1itz:A (2.3) BS01 MG 2.2.1.1 GO:0003824 ... Q7SIC9 12913150
    21571 1itz:A (2.3) BS02 TPP 2.2.1.1 GO:0003824 ... Q7SIC9 12913150
    21572 1itz:A (2.3) BS03 TPP 2.2.1.1 GO:0003824 ... Q7SIC9 12913150
    21573 1itz:B (2.3) BS01 TPP 2.2.1.1 GO:0003824 ... Q7SIC9 12913150
    21574 1itz:B (2.3) BS02 MG 2.2.1.1 GO:0003824 ... Q7SIC9 12913150
    21575 1itz:B (2.3) BS03 TPP 2.2.1.1 GO:0003824 ... Q7SIC9 12913150
    21576 1itz:C (2.3) BS01 MG 2.2.1.1 GO:0003824 ... Q7SIC9 12913150
    21577 1itz:C (2.3) BS02 TPP 2.2.1.1 GO:0003824 ... Q7SIC9 12913150
    21578 1iu3:C (3.0) BS01 dna ? GO:0003677 ... P0AFY8 14704346
    21579 1iu3:C (3.0) BS02 dna ? GO:0003677 ... P0AFY8 14704346
    21580 1iu3:F (3.0) BS01 dna ? GO:0003677 ... P0AFY8 14704346
    21581 1iu3:F (3.0) BS02 dna ? GO:0003677 ... P0AFY8 14704346
    21582 1iu5:A (1.5) BS01 FE ? GO:0005506 ... P24297 15272158
    21583 1iu6:A (1.6) BS01 FE ? GO:0009055 ... P24297 15272158
    21584 1iu7:A (1.8) BS01 CU 1.4.3.21 GO:0005507 ... P46881 12537504
    21585 1iu7:B (1.8) BS01 CU 1.4.3.21 GO:0005507 ... P46881 12537504
    21586 1iua:A (0.8) BS01 SF4 ? GO:0009055 ... P80176 12077426
    21587 1iub:A (2.31) BS01 FUL ? GO:0030246 ... P18891 14503859
    21588 1iub:A (2.31) BS02 FUL ? GO:0030246 ... P18891 14503859
    21589 1iuc:A (2.24) BS01 FUL ? GO:0030246 ... P18891 14503859
    21590 1iuc:A (2.24) BS02 FUL ? GO:0030246 ... P18891 14503859
    21591 1iuc:A (2.24) BS03 FUC ? GO:0030246 ... P18891 14503859
    21592 1iud:A (2.7) BS01 GLC ? GO:0008643 ... P0AEX9 9037707
    21593 1iud:A (2.7) BS02 GLC ? GO:0008643 ... P0AEX9 9037707
    21594 1iue:A (1.7) BS01 FES ? GO:0009055 ... Q8IED5 N/A
    21595 1iue:B (1.7) BS01 FES ? GO:0009055 ... Q8IED5 N/A
    21596 1iug:A (2.2) BS01 PO4 2.6.1.1 GO:0004069 ... P83786 15103612
    21597 1iug:B (2.2) BS01 PO4 2.6.1.1 GO:0004069 ... P83786 15103612
    21598 1iun:B (2.8) BS01 ACT 3.7.1.9 GO:0003824 ... P96965 12192074
    21599 1iuo:A (2.0) BS01 ACT 3.7.1.9 GO:0003824 ... P96965 12192074
    21600 1iuo:A (2.0) BS02 ACT 3.7.1.9 GO:0003824 ... P96965 12192074

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218