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BioLiP
Download all results in tab-seperated text for 832530 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    20001 1i48:E (3.25) BS02 CCO 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20002 1i48:E (3.25) BS03 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20003 1i48:F (3.25) BS01 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20004 1i48:F (3.25) BS02 CCO 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20005 1i48:F (3.25) BS03 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20006 1i48:G (3.25) BS01 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20007 1i48:G (3.25) BS02 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20008 1i48:G (3.25) BS03 CCO 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20009 1i48:H (3.25) BS01 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20010 1i48:H (3.25) BS02 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20011 1i48:H (3.25) BS03 CCO 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20012 1i48:I (3.25) BS01 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20013 1i48:I (3.25) BS02 CCO 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20014 1i48:I (3.25) BS03 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20015 1i48:J (3.25) BS01 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20016 1i48:J (3.25) BS02 CCO 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20017 1i48:J (3.25) BS03 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20018 1i48:K (3.25) BS01 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20019 1i48:K (3.25) BS02 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20020 1i48:K (3.25) BS03 CCO 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20021 1i48:L (3.25) BS01 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20022 1i48:L (3.25) BS02 PLP 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20023 1i48:L (3.25) BS03 CCO 4.2.99.9 GO:0003962 ... Q9ZPL5 11518531
    20024 1i4a:A (2.0) BS01 CA ? GO:0001786 ... P13214 11300800
    20025 1i4a:A (2.0) BS02 CA ? GO:0001786 ... P13214 11300800
    20026 1i4d:D (2.5) BS01 GDP 3.6.5.2 GO:0001764 ... P63000 11346801 MOAD: Kd=3uM
    20027 1i4f:A (1.4) BS01 peptide ? N/A P04439 11502003
    20028 1i4g:A (2.1) BS01 ZN ? GO:0005515 ... P0A0L2 11713682
    20029 1i4h:A (2.9) BS01 ZN ? GO:0005515 ... P0A0L2 11713682
    20030 1i4h:B (2.9) BS01 ZN ? GO:0005515 ... P0A0L2 11713682
    20031 1i4l:D (2.7) BS01 GDP 3.6.5.2 GO:0001764 ... P63000 11346801
    20032 1i4o:A (2.4) BS01 peptide 3.4.22.60 GO:0003723 ... P55210 11257231
    20033 1i4o:B (2.4) BS01 peptide 3.4.22.60 GO:0003723 ... P55210 11257231
    20034 1i4p:A (2.0) BS01 ZN ? GO:0005576 ... P34071 11526318
    20035 1i4q:A (2.2) BS01 ZN ? GO:0005576 ... P34071 11526318
    20036 1i4r:A (2.1) BS01 ZN ? GO:0005576 ... P34071 11526318
    20037 1i4t:D (2.6) BS01 GNP 3.6.5.2 GO:0001764 ... P63000 11346801
    20038 1i4x:A (2.4) BS01 ZN ? GO:0005576 ... P34071 11526318
    20039 1i4y:A (1.8) BS01 FEO ? GO:0005344 ... P02244 11372200
    20040 1i4y:B (1.8) BS01 FEO ? GO:0005344 ... P02244 11372200
    20041 1i4y:C (1.8) BS01 FEO ? GO:0005344 ... P02244 11372200
    20042 1i4y:D (1.8) BS01 FEO ? GO:0005344 ... P02244 11372200
    20043 1i4y:E (1.8) BS01 FEO ? GO:0005344 ... P02244 11372200
    20044 1i4y:F (1.8) BS01 FEO ? GO:0005344 ... P02244 11372200
    20045 1i4y:G (1.8) BS01 FEO ? GO:0005344 ... P02244 11372200
    20046 1i4y:H (1.8) BS01 FEO ? GO:0005344 ... P02244 11372200
    20047 1i4z:A (2.1) BS01 FEO ? GO:0005344 ... P02244 11372200
    20048 1i4z:B (2.1) BS01 FEO ? GO:0005344 ... P02244 11372200
    20049 1i4z:C (2.1) BS01 FEO ? GO:0005344 ... P02244 11372200
    20050 1i4z:D (2.1) BS01 FEO ? GO:0005344 ... P02244 11372200
    20051 1i4z:E (2.1) BS01 FEO ? GO:0005344 ... P02244 11372200
    20052 1i4z:F (2.1) BS01 FEO ? GO:0005344 ... P02244 11372200
    20053 1i4z:G (2.1) BS01 FEO ? GO:0005344 ... P02244 11372200
    20054 1i4z:H (2.1) BS01 FEO ? GO:0005344 ... P02244 11372200
    20055 1i50:A (2.8) BS01 ZN 2.7.7.6 GO:0000428 ... P04050 11313498
    20056 1i50:A (2.8) BS02 ZN 2.7.7.6 GO:0000428 ... P04050 11313498
    20057 1i50:A (2.8) BS03 MN 2.7.7.6 GO:0000428 ... P04050 11313498
    20058 1i50:B (2.8) BS01 ZN 2.7.7.6 GO:0000428 ... P08518 11313498
    20059 1i50:C (2.8) BS01 ZN 2.7.7.6 GO:0000428 ... P16370 11313498
    20060 1i50:I (2.8) BS01 ZN 2.7.7.6 GO:0000428 ... P27999 11313498
    20061 1i50:I (2.8) BS02 ZN 2.7.7.6 GO:0000428 ... P27999 11313498
    20062 1i50:J (2.8) BS01 ZN 2.7.7.6 GO:0000428 ... P22139 11313498
    20063 1i50:L (2.8) BS01 ZN 2.7.7.6 GO:0000428 ... P40422 11313498
    20064 1i51:A (2.45) BS01 peptide 3.4.22.60 GO:0004197 ... P55210 11257230
    20065 1i51:B (2.45) BS01 peptide 3.4.22.60 GO:0004197 ... P55210 11257230
    20066 1i51:C (2.45) BS01 peptide 3.4.22.60 GO:0004197 ... P55210 11257230
    20067 1i51:D (2.45) BS01 peptide 3.4.22.60 GO:0004197 ... P55210 11257230
    20068 1i52:A (1.5) BS01 CTP 2.7.7.60 GO:0000287 ... Q46893 11427897
    20069 1i53:A (1.8) BS01 CU ? GO:0005507 ... P00282 11457048
    20070 1i53:B (1.8) BS01 CU ? GO:0005507 ... P00282 11457048
    20071 1i54:A (1.5) BS01 HEC ? GO:0005739 ... P81459 11296248
    20072 1i54:A (1.5) BS02 ZNH ? GO:0005739 ... P81459 11296248
    20073 1i54:B (1.5) BS01 HEC ? GO:0005739 ... P81459 11296248
    20074 1i54:B (1.5) BS02 ZNH ? GO:0005739 ... P81459 11296248
    20075 1i55:A (2.0) BS01 HEC ? GO:0005739 ... P81459 11296248
    20076 1i55:A (2.0) BS02 ZNH ? GO:0005739 ... P81459 11296248
    20077 1i55:B (2.0) BS01 HEC ? GO:0005739 ... P81459 11296248
    20078 1i55:B (2.0) BS02 ZNH ? GO:0005739 ... P81459 11296248
    20079 1i58:A (1.6) BS01 ACP 2.7.13.3 GO:0016310 ... Q56310 11276258
    20080 1i58:B (1.6) BS01 ADP 2.7.13.3 GO:0016310 ... Q56310 11276258
    20081 1i59:A (1.8) BS01 ANP 2.7.13.3 GO:0016310 ... Q56310 11276258
    20082 1i59:B (1.8) BS01 ADP 2.7.13.3 GO:0016310 ... Q56310 11276258
    20083 1i5a:A (1.9) BS01 MN 2.7.13.3 GO:0016310 ... Q56310 11276258
    20084 1i5a:A (1.9) BS02 ACP 2.7.13.3 GO:0016310 ... Q56310 11276258
    20085 1i5a:B (1.9) BS01 MN 2.7.13.3 GO:0016310 ... Q56310 11276258
    20086 1i5a:B (1.9) BS02 ACP 2.7.13.3 GO:0016310 ... Q56310 11276258
    20087 1i5b:A (1.94) BS01 MN 2.7.13.3 GO:0016310 ... Q56310 11276258
    20088 1i5b:A (1.94) BS02 ANP 2.7.13.3 GO:0016310 ... Q56310 11276258
    20089 1i5b:B (1.94) BS01 MN 2.7.13.3 GO:0016310 ... Q56310 11276258
    20090 1i5b:B (1.94) BS02 ANP 2.7.13.3 GO:0016310 ... Q56310 11276258
    20091 1i5c:A (1.9) BS01 ADP 2.7.13.3 GO:0016310 ... Q56310 11276258
    20092 1i5c:B (1.9) BS01 ADP 2.7.13.3 GO:0016310 ... Q56310 11276258
    20093 1i5d:A (2.9) BS01 128 2.7.13.3 GO:0016310 ... Q56310 11276258 PDBbind: -logKd/Ki=8.00, Kd<0.010uM
    20094 1i5e:A (3.0) BS01 U5P 2.4.2.9 GO:0000287 ... P70881 12037295
    20095 1i5e:B (3.0) BS01 U5P 2.4.2.9 GO:0000287 ... P70881 12037295
    20096 1i5g:A (1.4) BS01 TS5 1.8.1.8 GO:0004791 ... O77093 11347894
    20097 1i5h:W (-1.00) BS01 peptide 2.3.2.26 N/A Q62940 11323714
    20098 1i5k:A (2.7) BS01 peptide 3.4.21.7 N/A P00747 11350170
    20099 1i5k:A (2.7) BS02 peptide 3.4.21.7 N/A P00747 11350170
    20100 1i5k:B (2.7) BS01 peptide 3.4.21.7 N/A P00747 11350170
    20101 1i5k:B (2.7) BS02 peptide 3.4.21.7 N/A P00747 11350170
    20102 1i5l:A (2.75) BS01 URI ? GO:0003723 ... O29386 11331594
    20103 1i5l:B (2.75) BS01 URI ? GO:0003723 ... O29386 11331594
    20104 1i5l:B (2.75) BS02 URI ? GO:0003723 ... O29386 11331594
    20105 1i5l:C (2.75) BS01 URI ? GO:0003723 ... O29386 11331594
    20106 1i5l:E (2.75) BS01 rna ? GO:0003723 ... O29386 11331594
    20107 1i5l:F (2.75) BS01 rna ? GO:0003723 ... O29386 11331594
    20108 1i5l:G (2.75) BS01 rna ? GO:0003723 ... O29386 11331594
    20109 1i5l:G (2.75) BS02 URI ? GO:0003723 ... O29386 11331594
    20110 1i5l:H (2.75) BS01 URI ? GO:0003723 ... O29386 11331594
    20111 1i5l:J (2.75) BS01 rna ? GO:0003723 ... O29386 11331594
    20112 1i5l:K (2.75) BS01 rna ? GO:0003723 ... O29386 11331594
    20113 1i5l:L (2.75) BS01 rna ? GO:0003723 ... O29386 11331594
    20114 1i5o:B (2.8) BS01 ZN ? GO:0005515 ... P0A7F3 11323717
    20115 1i5o:B (2.8) BS02 PAL ? GO:0005515 ... P0A7F3 11323717
    20116 1i5o:D (2.8) BS01 ZN ? GO:0005515 ... P0A7F3 11323717
    20117 1i5q:A (1.83) BS01 MOX 3.5.2.6 GO:0008800 ... P00811 11434768
    20118 1i5q:B (1.83) BS01 MOX 3.5.2.6 GO:0008800 ... P00811 11434768
    20119 1i5r:A (1.6) BS01 HYC 1.1.1.51
    1.1.1.62
    GO:0003824 ... P14061 12223444 MOAD: Ki=3nM
    PDBbind: -logKd/Ki=8.52, Ki=3.0nM
    BindingDB: IC50=52nM, Ki=3nM
    20120 1i5s:A (2.2) BS01 ADP ? GO:0003777 ... P33173 11373668
    20121 1i5t:A (-1.00) BS01 HEC ? GO:0005515 ... P00004 11941512
    20122 1i5u:A (-1.00) BS01 HEM ? GO:0020037 ... P00171 11714912
    20123 1i5z:A (1.9) BS01 CMP ? GO:0003677 ... P0ACJ8 N/A
    20124 1i5z:A (1.9) BS02 CMP ? GO:0003677 ... P0ACJ8 N/A
    20125 1i5z:B (1.9) BS01 CMP ? GO:0003677 ... P0ACJ8 N/A
    20126 1i6d:A (-1.00) BS01 HEC ? GO:0009055 ... P54820 11591150
    20127 1i6e:A (-1.00) BS01 HEC ? GO:0009055 ... P54820 11591150
    20128 1i6h:A (3.3) BS01 dna 2.7.7.6 GO:0000428 ... P04050 11313499
    20129 1i6h:A (3.3) BS02 rna 2.7.7.6 GO:0000428 ... P04050 11313499
    20130 1i6h:A (3.3) BS03 MG 2.7.7.6 GO:0000428 ... P04050 11313499
    20131 1i6h:A (3.3) BS04 ZN 2.7.7.6 GO:0000428 ... P04050 11313499
    20132 1i6h:B (3.3) BS01 dna 2.7.7.6 GO:0000428 ... P08518 11313499
    20133 1i6h:B (3.3) BS02 rna 2.7.7.6 GO:0000428 ... P08518 11313499
    20134 1i6h:B (3.3) BS03 ZN 2.7.7.6 GO:0000428 ... P08518 11313499
    20135 1i6h:C (3.3) BS01 ZN 2.7.7.6 GO:0000428 ... P16370 11313499
    20136 1i6h:I (3.3) BS01 ZN 2.7.7.6 GO:0000428 ... P27999 11313499
    20137 1i6h:I (3.3) BS02 ZN 2.7.7.6 GO:0000428 ... P27999 11313499
    20138 1i6h:J (3.3) BS01 ZN 2.7.7.6 GO:0000428 ... P22139 11313499
    20139 1i6h:L (3.3) BS01 ZN 2.7.7.6 GO:0000428 ... P40422 11313499
    20140 1i6i:A (2.0) BS01 ACP ? GO:0003777 ... P33173 11373668
    20141 1i6j:A (2.0) BS01 dna 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.26.4
    3.4.23.-
    N/A P03355 11526315
    20142 1i6j:A (2.0) BS02 dna 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.26.4
    3.4.23.-
    N/A P03355 11526315
    20143 1i6k:A (1.72) BS01 TYM 6.1.1.2 GO:0000166 ... P00953 11679724
    20144 1i6l:A (1.72) BS01 TYM 6.1.1.2 GO:0000166 ... P00953 11679724
    20145 1i6m:A (1.72) BS01 TYM 6.1.1.2 GO:0000166 ... P00953 11679724
    20146 1i6n:A (1.8) BS01 ZN 5.3.99.11 GO:0016853 ... P42419 12112707
    20147 1i6o:A (2.2) BS01 ZN 4.2.1.1 GO:0004089 ... P61517 11316870
    20148 1i6o:B (2.2) BS01 ZN 4.2.1.1 GO:0004089 ... P61517 11316870
    20149 1i6p:A (2.0) BS01 ZN 4.2.1.1 GO:0004089 ... P61517 11316870
    20150 1i6q:A (2.7) BS01 FE 3.4.21.- GO:0001503 ... Q9TUM0 11473113
    20151 1i6q:A (2.7) BS02 FE 3.4.21.- GO:0001503 ... Q9TUM0 11473113
    20152 1i6t:A (1.2) BS01 CA 3.6.1.1 GO:0000287 ... P0A7A9 11846572
    20153 1i6t:A (1.2) BS02 CA 3.6.1.1 GO:0000287 ... P0A7A9 11846572
    20154 1i6t:A (1.2) BS03 POP 3.6.1.1 GO:0000287 ... P0A7A9 11846572
    20155 1i6u:A (2.6) BS01 rna ? GO:0003735 ... P54041 11478863
    20156 1i6u:B (2.6) BS01 rna ? GO:0003735 ... P54041 11478863
    20157 1i6u:B (2.6) BS02 rna ? GO:0003735 ... P54041 11478863
    20158 1i6v:C (3.3) BS01 RFP 2.7.7.6 GO:0000428 ... Q9KWU7 11290327 PDBbind: -logKd/Ki=5.00, Ki=10uM
    20159 1i6v:D (3.3) BS01 MG 2.7.7.6 GO:0003677 ... Q9KWU6 11290327
    20160 1i6v:D (3.3) BS02 ZN 2.7.7.6 GO:0003677 ... Q9KWU6 11290327
    20161 1i6x:A (2.2) BS01 CMP ? GO:0003677 ... P0ACJ8 N/A
    20162 1i6x:A (2.2) BS02 CMP ? GO:0003677 ... P0ACJ8 N/A
    20163 1i6x:B (2.2) BS01 CMP ? GO:0003677 ... P0ACJ8 N/A
    20164 1i72:A (2.0) BS01 MAO 4.1.1.50 GO:0004014 ... P17707 11583147 PDBbind: -logKd/Ki=7.26, IC50=55nM
    BindingDB: IC50=55nM
    20165 1i72:A (2.0) BS02 PUT 4.1.1.50 GO:0004014 ... P17707 11583147
    20166 1i72:B (2.0) BS01 MAO 4.1.1.50 GO:0004014 ... P17707 11583147 PDBbind: -logKd/Ki=7.26, IC50=55nM
    BindingDB: IC50=55nM
    20167 1i73:A (1.4) BS01 peptide 3.4.24.34 GO:0004222 ... P22894 10978185
    20168 1i73:A (1.4) BS02 CA 3.4.24.34 GO:0004222 ... P22894 10978185
    20169 1i73:A (1.4) BS03 CA 3.4.24.34 GO:0004222 ... P22894 10978185
    20170 1i73:A (1.4) BS04 ZN 3.4.24.34 GO:0004222 ... P22894 10978185
    20171 1i73:A (1.4) BS05 ZN 3.4.24.34 GO:0004222 ... P22894 10978185
    20172 1i74:A (2.2) BS01 MN 3.6.1.1 GO:0004427 ... O68579 11525166
    20173 1i74:A (2.2) BS02 MN 3.6.1.1 GO:0004427 ... O68579 11525166
    20174 1i74:A (2.2) BS03 SO4 3.6.1.1 GO:0004427 ... O68579 11525166
    20175 1i74:A (2.2) BS04 SO4 3.6.1.1 GO:0004427 ... O68579 11525166
    20176 1i74:B (2.2) BS01 MN 3.6.1.1 GO:0004427 ... O68579 11525166
    20177 1i74:B (2.2) BS02 MN 3.6.1.1 GO:0004427 ... O68579 11525166
    20178 1i74:B (2.2) BS03 SO4 3.6.1.1 GO:0004427 ... O68579 11525166
    20179 1i75:A (2.0) BS01 CA 2.4.1.19 GO:0003824 ... P05618 11275559
    20180 1i75:A (2.0) BS02 CA 2.4.1.19 GO:0003824 ... P05618 11275559
    20181 1i75:A (2.0) BS03 NOJ 2.4.1.19 GO:0003824 ... P05618 11275559
    20182 1i75:A (2.0) BS04 NOJ 2.4.1.19 GO:0003824 ... P05618 11275559
    20183 1i75:B (2.0) BS01 CA 2.4.1.19 GO:0003824 ... P05618 11275559
    20184 1i75:B (2.0) BS02 CA 2.4.1.19 GO:0003824 ... P05618 11275559
    20185 1i75:B (2.0) BS03 NOJ 2.4.1.19 GO:0003824 ... P05618 11275559
    20186 1i75:B (2.0) BS04 NOJ 2.4.1.19 GO:0003824 ... P05618 11275559
    20187 1i76:A (1.2) BS01 CA 3.4.24.34 GO:0004222 ... P22894 10978185
    20188 1i76:A (1.2) BS02 CA 3.4.24.34 GO:0004222 ... P22894 10978185
    20189 1i76:A (1.2) BS03 ZN 3.4.24.34 GO:0004222 ... P22894 10978185
    20190 1i76:A (1.2) BS04 ZN 3.4.24.34 GO:0004222 ... P22894 10978185
    20191 1i76:A (1.2) BS05 BSI 3.4.24.34 GO:0004222 ... P22894 10978185
    20192 1i77:A (1.95) BS01 HEM ? GO:0009055 ... Q9L915 11358521
    20193 1i77:A (1.95) BS02 HEM ? GO:0009055 ... Q9L915 11358521
    20194 1i77:A (1.95) BS03 HEM ? GO:0009055 ... Q9L915 11358521
    20195 1i77:A (1.95) BS04 HEM ? GO:0009055 ... Q9L915 11358521
    20196 1i79:A (2.01) BS01 MHZ 4.1.1.50 GO:0004014 ... P17707 11583147
    20197 1i79:A (2.01) BS02 PUT 4.1.1.50 GO:0004014 ... P17707 11583147
    20198 1i79:B (2.01) BS01 MHZ 4.1.1.50 GO:0004014 ... P17707 11583147
    20199 1i7a:A (2.24) BS01 peptide ? GO:0007216 ... Q9QWW1 11491285
    20200 1i7a:B (2.24) BS01 peptide ? GO:0007216 ... Q9QWW1 11491285

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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