Protein-Peptide binding predictions with DeepMSAFold-Multimer

[SLarmadillo]

Hi,

Thanks to everyone in Zhang Lab for making DeepMSAFold-Multimer an astonishing success!

A question regarding the application of DeepMSAFold in Protein-Peptide interactions:
Will the DeepMSAFold-Multimer server or the source code version (if available later) support giving short peptide chains as input? e.g., under 15 aa. The current minimum on the DeepMSAFold-Multimer server requires chains as input to have at least 30 aa chains.

best,
Songyuan

[jlspzw]

Dear user,

We have temporarily changed it to 10, so you can try it if it works. For very short peptides (<10AA), we are not sure if it could get a reasonable result since we do not have any benchmark on it.

Best
IT Team