| Swiss ID: gnrhr_human |
| Protein Name: Gonadotropin-releasing hormone (GnRH receptor) (Gn |
| Organism: Human |
| Seqeunce Length: 328 |
| MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKL QKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL KLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRM IHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTR VLHQDPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRL SDPVNHFFFLFAFLNPCFDPLIYGYFSL |
| Multiple Sequence Alignment |
| Experimental Restraints: |
| Contact Restraint: N87-K121 PMID of associated paper: 10894158 |
| Contact Restraint: W280-F309 PMID of associated paper: 16420049 |
| Contact Restraint: F307-P282 PMID of associated paper: 9880506 |
| : MSA PMID of associated paper: 0 |
| Orientation Restraint: T51 PMID of associated paper: 16420049 |
| Orientation Restraint: D138 PMID of associated paper: 10894158 |
| Orientation Restraint: S168 PMID of associated paper: 16420049 |
| Orientation Restraint: F210 PMID of associated paper: 10894158 |
| Orientation Restraint: T215 PMID of associated paper: 10894158 |
| Orientation Restraint: F272 PMID of associated paper: 9820623 |
| Orientation Restraint: W280 PMID of associated paper: 16420049 |
| Orientation Restraint: Y284 PMID of associated paper: 11802711 |
| Orientation Restraint: W291 PMID of associated paper: 11802711 |
| Orientation Restraint: F292 PMID of associated paper: 11802711 |
| Orientation Restraint: F309 PMID of associated paper: 16420049 |
| Orientation Restraint: N315 PMID of associated paper: 16420049 |
| Experimental Data: |
| Experimental Data: M1T PMID of associated paper: 12568864 |
| Experimental Data: A2R PMID of associated paper: 15105440 |
| Experimental Data: E8Q PMID of associated paper: 9335546 |
| Experimental Data: N10K PMID of associated paper: 11397871 |
| Experimental Data: C14S PMID of associated paper: 9335546 |
| Experimental Data: M24A PMID of associated paper: 16420049 |
| Experimental Data: M24I PMID of associated paper: 16420049 |
| Experimental Data: M24T PMID of associated paper: 16420049 |
| Experimental Data: N27A PMID of associated paper: 16420049 |
| Experimental Data: N27E PMID of associated paper: 16420049 |
| Experimental Data: T32I PMID of associated paper: 11297587 |
| Experimental Data: K36A PMID of associated paper: 10894158 |
| Experimental Data: T51A PMID of associated paper: 16420049 |
| Experimental Data: N102 PMID of associated paper: 9414473 |
| Experimental Data: N102A PMID of associated paper: 10894158 |
| Experimental Data: N102D PMID of associated paper: 16420049 |
| Experimental Data: N102Q PMID of associated paper: 10894158 |
| Experimental Data: Q106A PMID of associated paper: 12679486 |
| Experimental Data: Q106R PMID of associated paper: 10022417 |
| Experimental Data: E111A PMID of associated paper: 16420049 |
| Experimental Data: E111K PMID of associated paper: 16420049 |
| Experimental Data: E111Q PMID of associated paper: 9335546 |
| Experimental Data: L112A PMID of associated paper: 16420049 |
| Experimental Data: L112F PMID of associated paper: 16420049 |
| Experimental Data: L112K PMID of associated paper: 16420049 |
| Experimental Data: C114S PMID of associated paper: 9335546 |
| Experimental Data: K115E PMID of associated paper: 16420049 |
| Experimental Data: K115Q PMID of associated paper: 16420049 |
| Experimental Data: D138A PMID of associated paper: 10894158 |
| Experimental Data: D138E PMID of associated paper: 10894158 |
| Experimental Data: D138N PMID of associated paper: 10894158 |
| Experimental Data: R139H PMID of associated paper: 11397871 |
| Experimental Data: R139Q PMID of associated paper: 11397871 |
| Experimental Data: I143A PMID of associated paper: 10894158 |
| Experimental Data: R145P PMID of associated paper: 10585457 |
| Experimental Data: S168A PMID of associated paper: 16420049 |
| Experimental Data: S168I PMID of associated paper: 16420049 |
| Experimental Data: S168R PMID of associated paper: 10523035 |
| Experimental Data: H182A PMID of associated paper: 16420049 |
| Experimental Data: H182E PMID of associated paper: 16420049 |
| Experimental Data: H182Y PMID of associated paper: 10379888 |
| Experimental Data: S186D PMID of associated paper: 16420049 |
| Experimental Data: S186G PMID of associated paper: 10379888 |
| Experimental Data: S186K PMID of associated paper: 16420049 |
| Experimental Data: Q189A PMID of associated paper: 16420049 |
| Experimental Data: Q189E PMID of associated paper: 16420049 |
| Experimental Data: Q189K PMID of associated paper: 16420049 |
| Experimental Data: Q189P PMID of associated paper: 10379888 |
| Experimental Data: T190K PMID of associated paper: 16420049 |
| Experimental Data: K191A PMID of associated paper: 10379888 |
| Experimental Data: K191E PMID of associated paper: 10379888 |
| Experimental Data: K191G PMID of associated paper: 15886197 |
| Experimental Data: K191Q PMID of associated paper: 10379888 |
| Experimental Data: K191R PMID of associated paper: 10379888 |
| Experimental Data: C196S PMID of associated paper: 9335546 |
| Experimental Data: C200S PMID of associated paper: 9335546 |
| Experimental Data: C200Y PMID of associated paper: 11297587 |
| Experimental Data: S203E PMID of associated paper: 16420049 |
| Experimental Data: S203K PMID of associated paper: 16420049 |
| Experimental Data: S203P PMID of associated paper: 10379888 |
| Experimental Data: S203Q PMID of associated paper: 16420049 |
| Experimental Data: Q204A PMID of associated paper: 10894158 |
| Experimental Data: W205A PMID of associated paper: 10894158 |
| Experimental Data: H207A PMID of associated paper: 10894158 |
| Experimental Data: Q208A PMID of associated paper: 10894158 |
| Experimental Data: Q208D PMID of associated paper: 16420049 |
| Experimental Data: Q208E PMID of associated paper: 16420049 |
| Experimental Data: F210A PMID of associated paper: 10894158 |
| Experimental Data: T215A PMID of associated paper: 10894158 |
| Experimental Data: A261E PMID of associated paper: 9560319 |
| Experimental Data: A261F PMID of associated paper: 9560319 |
| Experimental Data: A261G PMID of associated paper: 9560319 |
| Experimental Data: A261I PMID of associated paper: 9560319 |
| Experimental Data: A261K PMID of associated paper: 9560319 |
| Experimental Data: A261L PMID of associated paper: 9560319 |
| Experimental Data: A261P PMID of associated paper: 9560319 |
| Experimental Data: A261S PMID of associated paper: 9560319 |
| Experimental Data: A261V PMID of associated paper: 9560319 |
| Experimental Data: R262Q PMID of associated paper: 10022417 |
| Experimental Data: L266R PMID of associated paper: 11297587 |
| Experimental Data: F272L PMID of associated paper: 9820623 |
| Experimental Data: W280F PMID of associated paper: 16420049 |
| Experimental Data: Y284A PMID of associated paper: 11802711 |
| Experimental Data: Y284C PMID of associated paper: 10022417 |
| Experimental Data: Y284F PMID of associated paper: 16420049 |
| Experimental Data: Y284L PMID of associated paper: 16420049 |
| Experimental Data: W291A PMID of associated paper: 11802711 |
| Experimental Data: W291F PMID of associated paper: 16420049 |
| Experimental Data: F292A PMID of associated paper: 11802711 |
| Experimental Data: D293A PMID of associated paper: 16420049 |
| Experimental Data: D293E PMID of associated paper: 16420049 |
| Experimental Data: D293K PMID of associated paper: 16420049 |
| Experimental Data: D293N PMID of associated paper: 16420049 |
| Experimental Data: E295A PMID of associated paper: 16420049 |
| Experimental Data: E295K PMID of associated paper: 16420049 |
| Experimental Data: E295Q PMID of associated paper: 16420049 |
| Experimental Data: L300A PMID of associated paper: 16420049 |
| Experimental Data: L300K PMID of associated paper: 16420049 |
| Experimental Data: L300V PMID of associated paper: 16420049 |
| Experimental Data: D302A PMID of associated paper: 16420049 |
| Experimental Data: D302N PMID of associated paper: 9751490 |
| Experimental Data: D302Q PMID of associated paper: 16420049 |
| Experimental Data: N305A PMID of associated paper: 16420049 |
| Experimental Data: N305D PMID of associated paper: 16420049 |
| Experimental Data: N305K PMID of associated paper: 16420049 |
| Experimental Data: H306A PMID of associated paper: 16420049 |
| Experimental Data: H306E PMID of associated paper: 16420049 |
| Experimental Data: H306K PMID of associated paper: 16420049 |
| Experimental Data: F309L PMID of associated paper: 16420049 |
| Experimental Data: F309Q PMID of associated paper: 16420049 |
| Experimental Data: N315A PMID of associated paper: 16420049 |
| Experimental Data: N315D PMID of associated paper: 16420049 |
| Experimental Data: R299 PMID of associated paper: 9880506 |
| Experimental Data: N298 PMID of associated paper: 9880506 |
| Experimental Data: D293 PMID of associated paper: 9880506 |
| Experimental Data: E295 PMID of associated paper: 9880506 |
| Experimental Data: L297 PMID of associated paper: 9880506 |
| Experimental Data: L300 PMID of associated paper: 9880506 |
| Experimental Data: M296 PMID of associated paper: 9880506 |
| Experimental Data: P294 PMID of associated paper: 9880506 |
| Experimental Data: N87-K121 PMID of associated paper: 10894158 |
| Experimental Data: W280-F309 PMID of associated paper: 16420049 |
| Experimental Data: F307-P282 PMID of associated paper: 9880506 |
| Experimental Data: A50T PMID of associated paper: 16420049 |
| Experimental Data: T51A PMID of associated paper: 16420049 |
| Experimental Data: N87A PMID of associated paper: 10894158 |
| Experimental Data: N87D PMID of associated paper: 10894158 |
| Experimental Data: E90A PMID of associated paper: 10894158 |
| Experimental Data: E90K PMID of associated paper: 12606630 |
| Experimental Data: E90Q PMID of associated paper: 9335546 |
| Experimental Data: D98A PMID of associated paper: 10894158 |
| Experimental Data: D98N PMID of associated paper: 10894158 |
| Experimental Data: W101A PMID of associated paper: 10894158 |
| Experimental Data: L117A PMID of associated paper: 16420049 |
| Experimental Data: S118A PMID of associated paper: 16420049 |
| Experimental Data: S118D PMID of associated paper: 16420049 |
| Experimental Data: S118N PMID of associated paper: 16420049 |
| Experimental Data: K121 PMID of associated paper: 9414473 |
| Experimental Data: K121A PMID of associated paper: 16420049 |
| Experimental Data: K121E PMID of associated paper: 16420049 |
| Experimental Data: K121L PMID of associated paper: 10894158 |
| Experimental Data: K121Q PMID of associated paper: 10894158 |
| Experimental Data: S124A PMID of associated paper: 16420049 |
| Experimental Data: S124D PMID of associated paper: 16420049 |
| Experimental Data: A129D PMID of associated paper: 10523035 |
| Experimental Data: D138A PMID of associated paper: 10894158 |
| Experimental Data: D138E PMID of associated paper: 10894158 |
| Experimental Data: D138N PMID of associated paper: 10894158 |
| Experimental Data: S168A PMID of associated paper: 16420049 |
| Experimental Data: S168I PMID of associated paper: 16420049 |
| Experimental Data: S168R PMID of associated paper: 10523035 |
| Experimental Data: A171T PMID of associated paper: 12679486 |
| Experimental Data: F210A PMID of associated paper: 10894158 |
| Experimental Data: N212A PMID of associated paper: 10894158 |
| Experimental Data: N212Q PMID of associated paper: 10894158 |
| Experimental Data: F213A PMID of associated paper: 10894158 |
| Experimental Data: T215A PMID of associated paper: 10894158 |
| Experimental Data: F216A PMID of associated paper: 10894158 |
| Experimental Data: F216Y PMID of associated paper: 10894158 |
| Experimental Data: S217A PMID of associated paper: 10894158 |
| Experimental Data: S217G PMID of associated paper: 15886197 |
| Experimental Data: S217R PMID of associated paper: 10022417 |
| Experimental Data: F272L PMID of associated paper: 9820623 |
| Experimental Data: C279Y PMID of associated paper: 11297587 |
| Experimental Data: W280F PMID of associated paper: 16420049 |
| Experimental Data: Y283A PMID of associated paper: 11802711 |
| Experimental Data: Y283C PMID of associated paper: 15886197 |
| Experimental Data: Y283F PMID of associated paper: 16420049 |
| Experimental Data: Y283L PMID of associated paper: 16420049 |
| Experimental Data: Y284A PMID of associated paper: 11802711 |
| Experimental Data: Y284C PMID of associated paper: 10022417 |
| Experimental Data: Y284F PMID of associated paper: 16420049 |
| Experimental Data: Y284L PMID of associated paper: 16420049 |
| Experimental Data: W289A PMID of associated paper: 11802711 |
| Experimental Data: Y290A PMID of associated paper: 11802711 |
| Experimental Data: Y290F PMID of associated paper: 16420049 |
| Experimental Data: Y290L PMID of associated paper: 16420049 |
| Experimental Data: Y290Q PMID of associated paper: 16420049 |
| Experimental Data: W291A PMID of associated paper: 11802711 |
| Experimental Data: W291F PMID of associated paper: 16420049 |
| Experimental Data: F292A PMID of associated paper: 11802711 |
| Experimental Data: F309L PMID of associated paper: 16420049 |
| Experimental Data: F309Q PMID of associated paper: 16420049 |
| Experimental Data: F313L PMID of associated paper: 16420049 |
| Experimental Data: L314X PMID of associated paper: 10999776 |
| Experimental Data: N315A PMID of associated paper: 16420049 |
| Experimental Data: N315D PMID of associated paper: 16420049 |
| Experimental Data: K121R PMID of associated paper: 8643087 |
| Experimental Data: K121D PMID of associated paper: 8643087 |
| Experimental Data: A312 PMID of associated paper: 9880506 |
| Experimental Data: N315 PMID of associated paper: 9880506 |
| Experimental Data: D319 PMID of associated paper: 9880506 |
| Experimental Data: C317 PMID of associated paper: 9880506 |
| Experimental Data: G287 PMID of associated paper: 9880506 |
| Experimental Data: G324 PMID of associated paper: 9880506 |
| Experimental Data: I288 PMID of associated paper: 9880506 |
| Experimental Data: I322 PMID of associated paper: 9880506 |
| Experimental Data: L286 PMID of associated paper: 9880506 |
| Experimental Data: L310 PMID of associated paper: 9880506 |
| Experimental Data: L314 PMID of associated paper: 9880506 |
| Experimental Data: L321 PMID of associated paper: 9880506 |
| Experimental Data: F292 PMID of associated paper: 9880506 |
| Experimental Data: F307 PMID of associated paper: 9880506 |
| Experimental Data: F308 PMID of associated paper: 9880506 |
| Experimental Data: F309 PMID of associated paper: 9880506 |
| Experimental Data: F311 PMID of associated paper: 9880506 |
| Experimental Data: F313 PMID of associated paper: 9880506 |
| Experimental Data: F318 PMID of associated paper: 9880506 |
| Experimental Data: F326 PMID of associated paper: 9880506 |
| Experimental Data: P282 PMID of associated paper: 9880506 |
| Experimental Data: P316 PMID of associated paper: 9880506 |
| Experimental Data: P320 PMID of associated paper: 9880506 |
| Experimental Data: W289 PMID of associated paper: 9880506 |
| Experimental Data: W291 PMID of associated paper: 9880506 |
| Experimental Data: Y283 PMID of associated paper: 9880506 |
| Experimental Data: Y284 PMID of associated paper: 9880506 |
| Experimental Data: Y290 PMID of associated paper: 9880506 |
| Experimental Data: Y323 PMID of associated paper: 9880506 |
| Experimental Data: Y325 PMID of associated paper: 9880506 |
| Experimental Data: V285 PMID of associated paper: 9880506 |
| Experimental Data: MSA PMID of associated paper: 0 |
| GPCR Related Corss-reference Links: |
| GPCRDB GPCR-OKB UniProt_P30968 |