| Swiss ID: ghrhr_human |
| Protein Name: Growth hormone-releasing hormone (GRFR) |
| Organism: Human |
| Seqeunce Length: 423 |
| MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF LNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPL ELGLGSFQGFIVAILYCFLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKVLT SMC |
| Multiple Sequence Alignment |
| Experimental Restraints: |
| Contact Restraint: G249-G287 PMID of associated paper: 8395283 |
| Contact Restraint: G363-H137 PMID of associated paper: 8395283 |
| Contact Restraint: P253-P288 PMID of associated paper: 8395283 |
| Contact Restraint: S366-T134 PMID of associated paper: 8395283 |
| Contact Restraint: Y281-Y342 PMID of associated paper: 8395283 |
| : MSA PMID of associated paper: 0 |
| Orientation Restraint: H137 PMID of associated paper: 16135671 |
| Orientation Restraint: L144 PMID of associated paper: 12100073 |
| Orientation Restraint: V254 PMID of associated paper: 11502843 |
| Experimental Data: |
| Experimental Data: D60G PMID of associated paper: 9029497 |
| Experimental Data: E72X PMID of associated paper: 10549302 |
| Experimental Data: P113L PMID of associated paper: 11502843 |
| Experimental Data: E121D PMID of associated paper: 11502843 |
| Experimental Data: H137L PMID of associated paper: 16135671 |
| Experimental Data: H137Y PMID of associated paper: 11502843 |
| Experimental Data: L144H PMID of associated paper: 12100073 |
| Experimental Data: A176V PMID of associated paper: 12534354 |
| Experimental Data: D183N PMID of associated paper: 11502843 |
| Experimental Data: A222E PMID of associated paper: 16135671 |
| Experimental Data: V225I PMID of associated paper: 11502843 |
| Experimental Data: V254M PMID of associated paper: 11502843 |
| Experimental Data: S262N PMID of associated paper: 11502843 |
| Experimental Data: K329E PMID of associated paper: 16135671 |
| Experimental Data: T410P PMID of associated paper: 11502843 |
| Experimental Data: C423Y PMID of associated paper: 11502843 |
| Experimental Data: A176 PMID of associated paper: 8395283 |
| Experimental Data: A178 PMID of associated paper: 8395283 |
| Experimental Data: A207 PMID of associated paper: 8395283 |
| Experimental Data: A208 PMID of associated paper: 8395283 |
| Experimental Data: A212 PMID of associated paper: 8395283 |
| Experimental Data: A222 PMID of associated paper: 8395283 |
| Experimental Data: A224 PMID of associated paper: 8395283 |
| Experimental Data: A241 PMID of associated paper: 8395283 |
| Experimental Data: N216 PMID of associated paper: 8395283 |
| Experimental Data: Q167 PMID of associated paper: 8395283 |
| Experimental Data: Q381 PMID of associated paper: 8395283 |
| Experimental Data: E223 PMID of associated paper: 8395283 |
| Experimental Data: G177 PMID of associated paper: 8395283 |
| Experimental Data: H165 PMID of associated paper: 8395283 |
| Experimental Data: H210 PMID of associated paper: 8395283 |
| Experimental Data: I173 PMID of associated paper: 8395283 |
| Experimental Data: I304 PMID of associated paper: 8395283 |
| Experimental Data: L168 PMID of associated paper: 8395283 |
| Experimental Data: L174 PMID of associated paper: 8395283 |
| Experimental Data: L181 PMID of associated paper: 8395283 |
| Experimental Data: L220 PMID of associated paper: 8395283 |
| Experimental Data: L221 PMID of associated paper: 8395283 |
| Experimental Data: L227 PMID of associated paper: 8395283 |
| Experimental Data: K175 PMID of associated paper: 8395283 |
| Experimental Data: M214 PMID of associated paper: 8395283 |
| Experimental Data: F169 PMID of associated paper: 8395283 |
| Experimental Data: F172 PMID of associated paper: 8395283 |
| Experimental Data: F180 PMID of associated paper: 8395283 |
| Experimental Data: F211 PMID of associated paper: 8395283 |
| Experimental Data: F217 PMID of associated paper: 8395283 |
| Experimental Data: S205 PMID of associated paper: 8395283 |
| Experimental Data: S209 PMID of associated paper: 8395283 |
| Experimental Data: S218 PMID of associated paper: 8395283 |
| Experimental Data: S262 PMID of associated paper: 8395283 |
| Experimental Data: S330 PMID of associated paper: 8395283 |
| Experimental Data: T166 PMID of associated paper: 8395283 |
| Experimental Data: T170 PMID of associated paper: 8395283 |
| Experimental Data: T171 PMID of associated paper: 8395283 |
| Experimental Data: T213 PMID of associated paper: 8395283 |
| Experimental Data: T215 PMID of associated paper: 8395283 |
| Experimental Data: W219 PMID of associated paper: 8395283 |
| Experimental Data: Y163 PMID of associated paper: 8395283 |
| Experimental Data: Y226 PMID of associated paper: 8395283 |
| Experimental Data: V164 PMID of associated paper: 8395283 |
| Experimental Data: V179 PMID of associated paper: 8395283 |
| Experimental Data: V206 PMID of associated paper: 8395283 |
| Experimental Data: V225 PMID of associated paper: 8395283 |
| Experimental Data: G249-G287 PMID of associated paper: 8395283 |
| Experimental Data: G363-H137 PMID of associated paper: 8395283 |
| Experimental Data: P253-P288 PMID of associated paper: 8395283 |
| Experimental Data: S366-T134 PMID of associated paper: 8395283 |
| Experimental Data: Y281-Y342 PMID of associated paper: 8395283 |
| Experimental Data: H137L PMID of associated paper: 16135671 |
| Experimental Data: H137Y PMID of associated paper: 11502843 |
| Experimental Data: L144H PMID of associated paper: 12100073 |
| Experimental Data: F242C PMID of associated paper: 16135671 |
| Experimental Data: W250X PMID of associated paper: 11502843 |
| Experimental Data: V254M PMID of associated paper: 11502843 |
| Experimental Data: G294R PMID of associated paper: 11502843 |
| Experimental Data: A143 PMID of associated paper: 8395283 |
| Experimental Data: A147 PMID of associated paper: 8395283 |
| Experimental Data: A248 PMID of associated paper: 8395283 |
| Experimental Data: A373 PMID of associated paper: 8395283 |
| Experimental Data: N296 PMID of associated paper: 8395283 |
| Experimental Data: N302 PMID of associated paper: 8395283 |
| Experimental Data: N346 PMID of associated paper: 8395283 |
| Experimental Data: N380 PMID of associated paper: 8395283 |
| Experimental Data: C377 PMID of associated paper: 8395283 |
| Experimental Data: Q368 PMID of associated paper: 8395283 |
| Experimental Data: G136 PMID of associated paper: 8395283 |
| Experimental Data: G249 PMID of associated paper: 8395283 |
| Experimental Data: G251 PMID of associated paper: 8395283 |
| Experimental Data: G258 PMID of associated paper: 8395283 |
| Experimental Data: G287 PMID of associated paper: 8395283 |
| Experimental Data: G294 PMID of associated paper: 8395283 |
| Experimental Data: G298 PMID of associated paper: 8395283 |
| Experimental Data: G339 PMID of associated paper: 8395283 |
| Experimental Data: G363 PMID of associated paper: 8395283 |
| Experimental Data: G365 PMID of associated paper: 8395283 |
| Experimental Data: G369 PMID of associated paper: 8395283 |
| Experimental Data: H137 PMID of associated paper: 8395283 |
| Experimental Data: H341 PMID of associated paper: 8395283 |
| Experimental Data: I139 PMID of associated paper: 8395283 |
| Experimental Data: I141 PMID of associated paper: 8395283 |
| Experimental Data: I148 PMID of associated paper: 8395283 |
| Experimental Data: I150 PMID of associated paper: 8395283 |
| Experimental Data: I284 PMID of associated paper: 8395283 |
| Experimental Data: I285 PMID of associated paper: 8395283 |
| Experimental Data: I289 PMID of associated paper: 8395283 |
| Experimental Data: I303 PMID of associated paper: 8395283 |
| Experimental Data: I335 PMID of associated paper: 8395283 |
| Experimental Data: I340 PMID of associated paper: 8395283 |
| Experimental Data: I343 PMID of associated paper: 8395283 |
| Experimental Data: I344 PMID of associated paper: 8395283 |
| Experimental Data: I371 PMID of associated paper: 8395283 |
| Experimental Data: I374 PMID of associated paper: 8395283 |
| Experimental Data: L144 PMID of associated paper: 8395283 |
| Experimental Data: L151 PMID of associated paper: 8395283 |
| Experimental Data: L245 PMID of associated paper: 8395283 |
| Experimental Data: L247 PMID of associated paper: 8395283 |
| Experimental Data: L252 PMID of associated paper: 8395283 |
| Experimental Data: L255 PMID of associated paper: 8395283 |
| Experimental Data: L291 PMID of associated paper: 8395283 |
| Experimental Data: L299 PMID of associated paper: 8395283 |
| Experimental Data: L301 PMID of associated paper: 8395283 |
| Experimental Data: L332 PMID of associated paper: 8395283 |
| Experimental Data: L334 PMID of associated paper: 8395283 |
| Experimental Data: L337 PMID of associated paper: 8395283 |
| Experimental Data: L348 PMID of associated paper: 8395283 |
| Experimental Data: L362 PMID of associated paper: 8395283 |
| Experimental Data: L364 PMID of associated paper: 8395283 |
| Experimental Data: L375 PMID of associated paper: 8395283 |
| Experimental Data: L379 PMID of associated paper: 8395283 |
| Experimental Data: K286 PMID of associated paper: 8395283 |
| Experimental Data: F145 PMID of associated paper: 8395283 |
| Experimental Data: F242 PMID of associated paper: 8395283 |
| Experimental Data: F256 PMID of associated paper: 8395283 |
| Experimental Data: F297 PMID of associated paper: 8395283 |
| Experimental Data: F300 PMID of associated paper: 8395283 |
| Experimental Data: F333 PMID of associated paper: 8395283 |
| Experimental Data: F338 PMID of associated paper: 8395283 |
| Experimental Data: F345 PMID of associated paper: 8395283 |
| Experimental Data: F347 PMID of associated paper: 8395283 |
| Experimental Data: F367 PMID of associated paper: 8395283 |
| Experimental Data: F370 PMID of associated paper: 8395283 |
| Experimental Data: F378 PMID of associated paper: 8395283 |
| Experimental Data: P253 PMID of associated paper: 8395283 |
| Experimental Data: P288 PMID of associated paper: 8395283 |
| Experimental Data: P336 PMID of associated paper: 8395283 |
| Experimental Data: S138 PMID of associated paper: 8395283 |
| Experimental Data: S140 PMID of associated paper: 8395283 |
| Experimental Data: S292 PMID of associated paper: 8395283 |
| Experimental Data: S366 PMID of associated paper: 8395283 |
| Experimental Data: T134 PMID of associated paper: 8395283 |
| Experimental Data: T149 PMID of associated paper: 8395283 |
| Experimental Data: T257 PMID of associated paper: 8395283 |
| Experimental Data: T259 PMID of associated paper: 8395283 |
| Experimental Data: T331 PMID of associated paper: 8395283 |
| Experimental Data: W243 PMID of associated paper: 8395283 |
| Experimental Data: W244 PMID of associated paper: 8395283 |
| Experimental Data: W250 PMID of associated paper: 8395283 |
| Experimental Data: W260 PMID of associated paper: 8395283 |
| Experimental Data: W282 PMID of associated paper: 8395283 |
| Experimental Data: W283 PMID of associated paper: 8395283 |
| Experimental Data: Y133 PMID of associated paper: 8395283 |
| Experimental Data: Y281 PMID of associated paper: 8395283 |
| Experimental Data: Y342 PMID of associated paper: 8395283 |
| Experimental Data: Y376 PMID of associated paper: 8395283 |
| Experimental Data: V135 PMID of associated paper: 8395283 |
| Experimental Data: V142 PMID of associated paper: 8395283 |
| Experimental Data: V146 PMID of associated paper: 8395283 |
| Experimental Data: V152 PMID of associated paper: 8395283 |
| Experimental Data: V246 PMID of associated paper: 8395283 |
| Experimental Data: V254 PMID of associated paper: 8395283 |
| Experimental Data: V261 PMID of associated paper: 8395283 |
| Experimental Data: V290 PMID of associated paper: 8395283 |
| Experimental Data: V293 PMID of associated paper: 8395283 |
| Experimental Data: V295 PMID of associated paper: 8395283 |
| Experimental Data: V372 PMID of associated paper: 8395283 |
| Experimental Data: MSA PMID of associated paper: 0 |
| GPCR Related Corss-reference Links: |
| GPCRDB GPCR-OKB UniProt_Q02643 |