| Swiss ID: acm5_human |
| Protein Name: Muscarinic acetylcholine M5 |
| Organism: Human |
| Seqeunce Length: 532 |
| MEGDSYHNATTVNGTPVNHQPLERHRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQ LKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMN LLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPL DECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVTKAE KRKPAHRALFRSCLRCPRPTLAQRERNQASWSSSRRSTSTTGKPSQATGPSANWAKAEQL TTCSSYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEETEETFVKAETEKSDYDTPN YLLSPAAAHRPKSQKCVAYKFRLVVKADGNQETNNGCHKVKIMPCPFPVAKEPSTKGLNP NPSHQMTKRKRVVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLG YWLCYVNSTVNPICYALCNRTFRKTFKMLLLCRWKKKKVEEKLYWQGNSKLP |
| Experimental Restraints: |
| Contact Restraint: I78-A163 PMID of associated paper: 8302281 |
| Contact Restraint: A163-A446 PMID of associated paper: 8302281 |
| Contact Restraint: A446-C498 PMID of associated paper: 8302281 |
| Contact Restraint: T37-L479 PMID of associated paper: 7642637 |
| Contact Restraint: L479-T32 PMID of associated paper: 7642637 |
| Experimental Data: |
| Experimental Data: R134A PMID of associated paper: 9733718 |
| Experimental Data: R134C PMID of associated paper: 9733718 |
| Experimental Data: R134D PMID of associated paper: 9733718 |
| Experimental Data: R134E PMID of associated paper: 9733718 |
| Experimental Data: R134G PMID of associated paper: 9733718 |
| Experimental Data: R134N PMID of associated paper: 9733718 |
| Experimental Data: R134Q PMID of associated paper: 9733718 |
| Experimental Data: R134T PMID of associated paper: 9733718 |
| Experimental Data: R134V PMID of associated paper: 9733718 |
| Experimental Data: R134X PMID of associated paper: 9733718 |
| Experimental Data: Y138A PMID of associated paper: 9733718 |
| Experimental Data: Y138C PMID of associated paper: 9733718 |
| Experimental Data: Y138G PMID of associated paper: 9733718 |
| Experimental Data: Y138M PMID of associated paper: 9733718 |
| Experimental Data: Y138S PMID of associated paper: 9733718 |
| Experimental Data: Y138T PMID of associated paper: 9733718 |
| Experimental Data: Y138V PMID of associated paper: 9733718 |
| Experimental Data: Y138X PMID of associated paper: 9733718 |
| Experimental Data: R139W PMID of associated paper: 9733718 |
| Experimental Data: R142A PMID of associated paper: 9733718 |
| Experimental Data: R142C PMID of associated paper: 9733718 |
| Experimental Data: R142D PMID of associated paper: 9733718 |
| Experimental Data: R142F PMID of associated paper: 9733718 |
| Experimental Data: R142G PMID of associated paper: 9733718 |
| Experimental Data: R142H PMID of associated paper: 9733718 |
| Experimental Data: R142L PMID of associated paper: 9733718 |
| Experimental Data: R142N PMID of associated paper: 9733718 |
| Experimental Data: R142Q PMID of associated paper: 9733718 |
| Experimental Data: R142S PMID of associated paper: 9733718 |
| Experimental Data: R142T PMID of associated paper: 9733718 |
| Experimental Data: R142W PMID of associated paper: 9733718 |
| Experimental Data: R142X PMID of associated paper: 9733718 |
| Experimental Data: I216 PMID of associated paper: 8621701 |
| Experimental Data: Y217 PMID of associated paper: 8621701 |
| Experimental Data: Y217S PMID of associated paper: 9521726 |
| Experimental Data: T220 PMID of associated paper: 8621701 |
| Experimental Data: R223 PMID of associated paper: 8621701 |
| Experimental Data: R223E PMID of associated paper: 9521726 |
| Experimental Data: K439E PMID of associated paper: 9521726 |
| Experimental Data: K439G PMID of associated paper: 9521726 |
| Experimental Data: A440E PMID of associated paper: 9521726 |
| Experimental Data: A440Q PMID of associated paper: 9521726 |
| Experimental Data: A440T PMID of associated paper: 9521726 |
| Experimental Data: A441K PMID of associated paper: 9521726 |
| Experimental Data: A441S PMID of associated paper: 9521726 |
| Experimental Data: A441T PMID of associated paper: 9521726 |
| Experimental Data: G148S PMID of associated paper: 9733718 |
| Experimental Data: G148C PMID of associated paper: 9733718 |
| Experimental Data: I149F PMID of associated paper: 9733718 |
| Experimental Data: A147T PMID of associated paper: 9733718 |
| Experimental Data: G148R PMID of associated paper: 9733718 |
| Experimental Data: I149M PMID of associated paper: 9733718 |
| Experimental Data: A147V PMID of associated paper: 9733718 |
| Experimental Data: G148A PMID of associated paper: 9733718 |
| Experimental Data: I149T PMID of associated paper: 9733718 |
| Experimental Data: A147S PMID of associated paper: 9733718 |
| Experimental Data: M150L PMID of associated paper: 9733718 |
| Experimental Data: I78-A163 PMID of associated paper: 8302281 |
| Experimental Data: A163-A446 PMID of associated paper: 8302281 |
| Experimental Data: A446-C498 PMID of associated paper: 8302281 |
| Experimental Data: T37-L479 PMID of associated paper: 7642637 |
| Experimental Data: L479-T32 PMID of associated paper: 7642637 |
| Experimental Data: Y129F PMID of associated paper: 9733718 |
| Experimental Data: F130C PMID of associated paper: 9733718 |
| Experimental Data: F130E PMID of associated paper: 9733718 |
| Experimental Data: F130G PMID of associated paper: 9733718 |
| Experimental Data: F130H PMID of associated paper: 9733718 |
| Experimental Data: F130K PMID of associated paper: 9733718 |
| Experimental Data: F130M PMID of associated paper: 9733718 |
| Experimental Data: F130Q PMID of associated paper: 9733718 |
| Experimental Data: F130R PMID of associated paper: 9733718 |
| Experimental Data: F130S PMID of associated paper: 9733718 |
| Experimental Data: F130T PMID of associated paper: 9733718 |
| Experimental Data: F130X PMID of associated paper: 9733718 |
| Experimental Data: Y213 PMID of associated paper: 8621701 |
| Experimental Data: C214 PMID of associated paper: 8621701 |
| Experimental Data: S465Y PMID of associated paper: 10496961 |
| Experimental Data: T466P PMID of associated paper: 10496961 |
| Experimental Data: S445L PMID of associated paper: 7852396 |
| Experimental Data: Y213F PMID of associated paper: 8621701 |
| Experimental Data: C214W PMID of associated paper: 8621701 |
| Experimental Data: L212V PMID of associated paper: 8621701 |
| Experimental Data: C214G PMID of associated paper: 8621701 |
| Experimental Data: Y213S PMID of associated paper: 8621701 |
| Experimental Data: C214S PMID of associated paper: 8621701 |
| Experimental Data: C214R PMID of associated paper: 8621701 |
| Experimental Data: L212F PMID of associated paper: 8621701 |
| Experimental Data: Y213D PMID of associated paper: 8621701 |
| Experimental Data: C214Y PMID of associated paper: 8621701 |
| Experimental Data: Y213H PMID of associated paper: 8621701 |
| Experimental Data: L212I PMID of associated paper: 8621701 |
| Experimental Data: Y213N PMID of associated paper: 8621701 |
| Experimental Data: C214F PMID of associated paper: 8621701 |
| Experimental Data: Y213C PMID of associated paper: 8621701 |
| Experimental Data: I78 PMID of associated paper: 8302281 |
| Experimental Data: A163 PMID of associated paper: 8302281 |
| Experimental Data: A446 PMID of associated paper: 8302281 |
| Experimental Data: C498 PMID of associated paper: 8302281 |
| Experimental Data: L77 PMID of associated paper: 1538713 |
| Experimental Data: T37 PMID of associated paper: 7642637 |
| Experimental Data: L479 PMID of associated paper: 7642637 |
| Experimental Data: T32 PMID of associated paper: 7642637 |
| Experimental Data: V39 PMID of associated paper: 7642637 |
| Experimental Data: N459H PMID of associated paper: 9705286 |
| Experimental Data: F451L PMID of associated paper: 9705286 |
| Experimental Data: M461T PMID of associated paper: 9705286 |
| Experimental Data: F451V PMID of associated paper: 9705286 |
| Experimental Data: T456A PMID of associated paper: 9705286 |
| Experimental Data: I452S PMID of associated paper: 9705286 |
| Experimental Data: I453S PMID of associated paper: 9705286 |
| Experimental Data: A446S PMID of associated paper: 9705286 |
| Experimental Data: L463P PMID of associated paper: 9705286 |
| Experimental Data: A446T PMID of associated paper: 9705286 |
| Experimental Data: N459I PMID of associated paper: 9705286 |
| Experimental Data: I453V PMID of associated paper: 9705286 |
| Experimental Data: L449M PMID of associated paper: 9705286 |
| Experimental Data: T456S PMID of associated paper: 9705286 |
| Experimental Data: N459K PMID of associated paper: 9705286 |
| Experimental Data: I447V PMID of associated paper: 9705286 |
| Experimental Data: I452T PMID of associated paper: 9705286 |
| Experimental Data: L463M PMID of associated paper: 9705286 |
| Experimental Data: A446G PMID of associated paper: 9705286 |
| Experimental Data: F451S PMID of associated paper: 9705286 |
| Experimental Data: I460S PMID of associated paper: 9705286 |
| Experimental Data: W455C PMID of associated paper: 9705286 |
| Experimental Data: A446V PMID of associated paper: 9705286 |
| Experimental Data: Y458H PMID of associated paper: 9705286 |
| Experimental Data: V464A PMID of associated paper: 9705286 |
| Experimental Data: I447M PMID of associated paper: 9705286 |
| Experimental Data: I452L PMID of associated paper: 9705286 |
| Experimental Data: I453L PMID of associated paper: 9705286 |
| Experimental Data: I447T PMID of associated paper: 9705286 |
| Experimental Data: I452M PMID of associated paper: 9705286 |
| Experimental Data: A446L PMID of associated paper: 9705286 |
| Experimental Data: L449S PMID of associated paper: 9705286 |
| Experimental Data: I460L PMID of associated paper: 9705286 |
| Experimental Data: A450S PMID of associated paper: 9705286 |
| Experimental Data: L448V PMID of associated paper: 9705286 |
| Experimental Data: F451T PMID of associated paper: 9705286 |
| Experimental Data: I447N PMID of associated paper: 9705286 |
| Experimental Data: L463V PMID of associated paper: 9705286 |
| Experimental Data: A450P PMID of associated paper: 9705286 |
| Experimental Data: I447L PMID of associated paper: 9705286 |
| Experimental Data: I452F PMID of associated paper: 9705286 |
| Experimental Data: A450G PMID of associated paper: 9705286 |
| Experimental Data: I460V PMID of associated paper: 9705286 |
| Experimental Data: I453C PMID of associated paper: 9705286 |
| Experimental Data: M461L PMID of associated paper: 9705286 |
| Experimental Data: L448H PMID of associated paper: 9705286 |
| Experimental Data: I460F PMID of associated paper: 9705286 |
| Experimental Data: A450V PMID of associated paper: 9705286 |
| Experimental Data: T456I PMID of associated paper: 9705286 |
| Experimental Data: F451C PMID of associated paper: 9705286 |
| Experimental Data: F451A PMID of associated paper: 9705286 |
| Experimental Data: F451Q PMID of associated paper: 9705286 |
| Experimental Data: F451N PMID of associated paper: 9705286 |
| Experimental Data: F451G PMID of associated paper: 9705286 |
| Experimental Data: F451W PMID of associated paper: 9705286 |
| Experimental Data: F451P PMID of associated paper: 9705286 |
| Experimental Data: N459S PMID of associated paper: 9705286 |
| Experimental Data: N459Y PMID of associated paper: 9705286 |
| Experimental Data: N459T PMID of associated paper: 9705286 |
| Experimental Data: N459Q PMID of associated paper: 9705286 |
| Experimental Data: N459C PMID of associated paper: 9705286 |
| Experimental Data: N459D PMID of associated paper: 9705286 |
| Experimental Data: N459A PMID of associated paper: 9705286 |
| Experimental Data: N459G PMID of associated paper: 9705286 |
| Experimental Data: N459V PMID of associated paper: 9705286 |
| Experimental Data: N459F PMID of associated paper: 9705286 |
| Experimental Data: I447S PMID of associated paper: 9705286 |
| Experimental Data: M461V PMID of associated paper: 9705286 |
| Experimental Data: S445N PMID of associated paper: 7852396 |
| Experimental Data: S445I PMID of associated paper: 7852396 |
| Experimental Data: L444P PMID of associated paper: 7852396 |
| Experimental Data: V464I PMID of associated paper: 10940778 |
| GPCR Related Corss-reference Links: |
| GPCRDB GPCR-OKB UniProt_P08912 |