| Swiss ID: acm2_human |
| Protein Name: Muscarinic acetylcholine M2 |
| Organism: Human |
| Seqeunce Length: 466 |
| MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR |
| Multiple Sequence Alignment |
| Experimental Restraints: |
| Contact Restraint: D103-W155 PMID of associated paper: 10513578 |
| Contact Restraint: N432-I392 PMID of associated paper: 8940100 |
| Contact Restraint: Y403-Y426 PMID of associated paper: 8940100 |
| : MSA PMID of associated paper: 0 |
| Orientation Restraint: T190 PMID of associated paper: 10513578 |
| Orientation Restraint: W400 PMID of associated paper: 10513578 |
| Orientation Restraint: Y403 PMID of associated paper: 10513578 |
| Orientation Restraint: N404 PMID of associated paper: 10513578 |
| Orientation Restraint: I389 PMID of associated paper: 7629074 |
| Experimental Data: |
| Experimental Data: Y177F PMID of associated paper: 11602604 |
| Experimental Data: T190A PMID of associated paper: 10513578 |
| Experimental Data: V385 PMID of associated paper: 9063897 |
| Experimental Data: T386 PMID of associated paper: 9063897 |
| Experimental Data: W400A PMID of associated paper: 10513578 |
| Experimental Data: Y403A PMID of associated paper: 10513578 |
| Experimental Data: N404A PMID of associated paper: 10513578 |
| Experimental Data: I389L PMID of associated paper: 7629074 |
| Experimental Data: A140 PMID of associated paper: 8050479 |
| Experimental Data: G141 PMID of associated paper: 8050479 |
| Experimental Data: D103-W155 PMID of associated paper: 10513578 |
| Experimental Data: N432-I392 PMID of associated paper: 8940100 |
| Experimental Data: Y403-Y426 PMID of associated paper: 8940100 |
| Experimental Data: D103A PMID of associated paper: 10513578 |
| Experimental Data: W155A PMID of associated paper: 10513578 |
| Experimental Data: T187A PMID of associated paper: 10513578 |
| Experimental Data: T190A PMID of associated paper: 10513578 |
| Experimental Data: I389 PMID of associated paper: 9063897 |
| Experimental Data: L390 PMID of associated paper: 9063897 |
| Experimental Data: W400A PMID of associated paper: 10513578 |
| Experimental Data: Y403A PMID of associated paper: 10513578 |
| Experimental Data: N404A PMID of associated paper: 10513578 |
| Experimental Data: D69N PMID of associated paper: 8190113 |
| Experimental Data: I389L PMID of associated paper: 7629074 |
| Experimental Data: L390S PMID of associated paper: 7629074 |
| Experimental Data: D103E PMID of associated paper: 10188794 |
| Experimental Data: D103N PMID of associated paper: 10188794 |
| Experimental Data: A391 PMID of associated paper: 8940100 |
| Experimental Data: A395 PMID of associated paper: 8940100 |
| Experimental Data: A401 PMID of associated paper: 8940100 |
| Experimental Data: A438 PMID of associated paper: 8940100 |
| Experimental Data: A441 PMID of associated paper: 8940100 |
| Experimental Data: N404 PMID of associated paper: 8940100 |
| Experimental Data: N432 PMID of associated paper: 8940100 |
| Experimental Data: N436 PMID of associated paper: 8940100 |
| Experimental Data: C429 PMID of associated paper: 8940100 |
| Experimental Data: C439 PMID of associated paper: 8940100 |
| Experimental Data: C443 PMID of associated paper: 8940100 |
| Experimental Data: G425 PMID of associated paper: 8940100 |
| Experimental Data: I392 PMID of associated paper: 8940100 |
| Experimental Data: I397 PMID of associated paper: 8940100 |
| Experimental Data: I398 PMID of associated paper: 8940100 |
| Experimental Data: I409 PMID of associated paper: 8940100 |
| Experimental Data: I424 PMID of associated paper: 8940100 |
| Experimental Data: I431 PMID of associated paper: 8940100 |
| Experimental Data: I435 PMID of associated paper: 8940100 |
| Experimental Data: L393 PMID of associated paper: 8940100 |
| Experimental Data: L394 PMID of associated paper: 8940100 |
| Experimental Data: L408 PMID of associated paper: 8940100 |
| Experimental Data: L428 PMID of associated paper: 8940100 |
| Experimental Data: L442 PMID of associated paper: 8940100 |
| Experimental Data: M406 PMID of associated paper: 8940100 |
| Experimental Data: F396 PMID of associated paper: 8940100 |
| Experimental Data: P402 PMID of associated paper: 8940100 |
| Experimental Data: P437 PMID of associated paper: 8940100 |
| Experimental Data: S433 PMID of associated paper: 8940100 |
| Experimental Data: T399 PMID of associated paper: 8940100 |
| Experimental Data: T434 PMID of associated paper: 8940100 |
| Experimental Data: W400 PMID of associated paper: 8940100 |
| Experimental Data: W427 PMID of associated paper: 8940100 |
| Experimental Data: Y403 PMID of associated paper: 8940100 |
| Experimental Data: Y426 PMID of associated paper: 8940100 |
| Experimental Data: Y430 PMID of associated paper: 8940100 |
| Experimental Data: Y440 PMID of associated paper: 8940100 |
| Experimental Data: V405 PMID of associated paper: 8940100 |
| Experimental Data: V407 PMID of associated paper: 8940100 |
| Experimental Data: I71 PMID of associated paper: 8302281 |
| Experimental Data: L70 PMID of associated paper: 1538713 |
| Experimental Data: A156 PMID of associated paper: 1538713 |
| Experimental Data: Y206 PMID of associated paper: 8621513 |
| Experimental Data: A401T PMID of associated paper: 10940778 |
| Experimental Data: MSA PMID of associated paper: 0 |
| GPCR Related Corss-reference Links: |
| GPCRDB GPCR-OKB UniProt_P08172 |