| Swiss ID: acm1_human |
| Protein Name: Muscarinic acetylcholine M1 |
| Organism: Human |
| Seqeunce Length: 460 |
| MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC |
| Multiple Sequence Alignment |
| Experimental Restraints: |
| Contact Restraint: T192-N382 PMID of associated paper: 10188986 |
| Contact Restraint: V127-L131 PMID of associated paper: 8120019 |
| : MSA PMID of associated paper: 0 |
| Orientation Restraint: D71 PMID of associated paper: 1618842 |
| Orientation Restraint: Y82 PMID of associated paper: 1488411 |
| Orientation Restraint: W209 PMID of associated paper: 7706286 |
| Orientation Restraint: N382 PMID of associated paper: 10188986 |
| Orientation Restraint: C417 PMID of associated paper: 12049494 |
| Orientation Restraint: S368 PMID of associated paper: 1618842 |
| Experimental Data: |
| Experimental Data: D71N PMID of associated paper: 1618842 |
| Experimental Data: Y82F PMID of associated paper: 1488411 |
| Experimental Data: V127A PMID of associated paper: 8120019 |
| Experimental Data: L131A PMID of associated paper: 8120019 |
| Experimental Data: L131D PMID of associated paper: 8226735 |
| Experimental Data: V173M PMID of associated paper: 12049494 |
| Experimental Data: W209A PMID of associated paper: 7706286 |
| Experimental Data: I211A PMID of associated paper: 7706286 |
| Experimental Data: Y212A PMID of associated paper: 7706286 |
| Experimental Data: E214A PMID of associated paper: 7706286 |
| Experimental Data: E216A PMID of associated paper: 7706286 |
| Experimental Data: E221A PMID of associated paper: 7706286 |
| Experimental Data: K359A PMID of associated paper: 7706286 |
| Experimental Data: E360A PMID of associated paper: 7706286 |
| Experimental Data: K361A PMID of associated paper: 7706286 |
| Experimental Data: K362A PMID of associated paper: 7706286 |
| Experimental Data: T366A PMID of associated paper: 7706286 |
| Experimental Data: N382A PMID of associated paper: 10188986 |
| Experimental Data: C417R PMID of associated paper: 12049494 |
| Experimental Data: C417S PMID of associated paper: 12049494 |
| Experimental Data: S368A PMID of associated paper: 1618842 |
| Experimental Data: T192-N382 PMID of associated paper: 10188986 |
| Experimental Data: D71N PMID of associated paper: 1618842 |
| Experimental Data: Y82F PMID of associated paper: 1488411 |
| Experimental Data: T192A PMID of associated paper: 10188986 |
| Experimental Data: W209A PMID of associated paper: 7706286 |
| Experimental Data: N382A PMID of associated paper: 10188986 |
| Experimental Data: S388Y PMID of associated paper: 10496961 |
| Experimental Data: T389P PMID of associated paper: 10496961 |
| Experimental Data: T389Y PMID of associated paper: 9732369 |
| Experimental Data: M416A PMID of associated paper: 10930431 |
| Experimental Data: C417R PMID of associated paper: 12049494 |
| Experimental Data: C417S PMID of associated paper: 12049494 |
| Experimental Data: S368A PMID of associated paper: 1618842 |
| Experimental Data: W101A PMID of associated paper: 7838137 |
| Experimental Data: W101F PMID of associated paper: 7838137 |
| Experimental Data: W164A PMID of associated paper: 7838137 |
| Experimental Data: Y404A PMID of associated paper: 7838137 |
| Experimental Data: Y404F PMID of associated paper: 7838137 |
| Experimental Data: V127-L131 PMID of associated paper: 8120019 |
| Experimental Data: MSA PMID of associated paper: 0 |
| GPCR Related Corss-reference Links: |
| GPCRDB GPCR-OKB UniProt_P11229 |