| Swiss ID: aa1r_human |
| Protein Name: Adenosine A1 |
| Organism: Human |
| Seqeunce Length: 326 |
| MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL KIWNDHFRCQPAPPIDEDLPEERPDD |
| Multiple Sequence Alignment |
| Experimental Restraints: |
| Contact Restraint: S50-S93 PMID of associated paper: 8967987 |
| Contact Restraint: S93-S135 PMID of associated paper: 8967987 |
| Contact Restraint: L65-M82 PMID of associated paper: 9920910 |
| : MSA PMID of associated paper: 0 |
| Orientation Restraint: E16 PMID of associated paper: 8967987 |
| Orientation Restraint: C46 PMID of associated paper: 11077047 |
| Orientation Restraint: C85 PMID of associated paper: 11077047 |
| Orientation Restraint: P86 PMID of associated paper: 9920910 |
| Orientation Restraint: Q92 PMID of associated paper: 11891221 |
| Orientation Restraint: L96 PMID of associated paper: 9920910 |
| Orientation Restraint: T270 PMID of associated paper: 11306703 |
| Orientation Restraint: Y271 PMID of associated paper: 11306703 |
| Orientation Restraint: I274 PMID of associated paper: 11306703 |
| Orientation Restraint: F275 PMID of associated paper: 11306703 |
| Orientation Restraint: T277 PMID of associated paper: 10722120 |
| Orientation Restraint: H278 PMID of associated paper: 11306703 |
| Orientation Restraint: S281 PMID of associated paper: 11306703 |
| Orientation Restraint: A282 PMID of associated paper: 11306703 |
| Orientation Restraint: P285 PMID of associated paper: 11306703 |
| Orientation Restraint: Y288 PMID of associated paper: 11306703 |
| Orientation Restraint: A289 PMID of associated paper: 11306703 |
| Orientation Restraint: S50 PMID of associated paper: 8967987 |
| Orientation Restraint: S93 PMID of associated paper: 8967987 |
| Experimental Data: |
| Experimental Data: E16A PMID of associated paper: 8967987 |
| Experimental Data: C46A PMID of associated paper: 11077047 |
| Experimental Data: C46S PMID of associated paper: 11077047 |
| Experimental Data: C80A PMID of associated paper: 11077047 |
| Experimental Data: C80S PMID of associated paper: 11077047 |
| Experimental Data: C85A PMID of associated paper: 11077047 |
| Experimental Data: C85S PMID of associated paper: 11077047 |
| Experimental Data: P86F PMID of associated paper: 9920910 |
| Experimental Data: Q92A PMID of associated paper: 11891221 |
| Experimental Data: L96F PMID of associated paper: 9920910 |
| Experimental Data: C169A PMID of associated paper: 11077047 |
| Experimental Data: C169S PMID of associated paper: 11077047 |
| Experimental Data: C260A PMID of associated paper: 11077047 |
| Experimental Data: C260S PMID of associated paper: 11077047 |
| Experimental Data: C263A PMID of associated paper: 11077047 |
| Experimental Data: C263S PMID of associated paper: 11077047 |
| Experimental Data: H264C PMID of associated paper: 11306703 |
| Experimental Data: K265C PMID of associated paper: 11306703 |
| Experimental Data: P266C PMID of associated paper: 11306703 |
| Experimental Data: S267C PMID of associated paper: 11306703 |
| Experimental Data: T270C PMID of associated paper: 11306703 |
| Experimental Data: Y271C PMID of associated paper: 11306703 |
| Experimental Data: I274C PMID of associated paper: 11306703 |
| Experimental Data: F275C PMID of associated paper: 11306703 |
| Experimental Data: T277A PMID of associated paper: 10722120 |
| Experimental Data: T277C PMID of associated paper: 11306703 |
| Experimental Data: T277S PMID of associated paper: 8300561 |
| Experimental Data: H278C PMID of associated paper: 11306703 |
| Experimental Data: H278L PMID of associated paper: 11306703 |
| Experimental Data: S281C PMID of associated paper: 11306703 |
| Experimental Data: A282C PMID of associated paper: 11306703 |
| Experimental Data: P285C PMID of associated paper: 11306703 |
| Experimental Data: Y288C PMID of associated paper: 11306703 |
| Experimental Data: A289C PMID of associated paper: 11306703 |
| Experimental Data: R291C PMID of associated paper: 11306703 |
| Experimental Data: I292C PMID of associated paper: 11306703 |
| Experimental Data: Q293C PMID of associated paper: 11306703 |
| Experimental Data: K294C PMID of associated paper: 11306703 |
| Experimental Data: F295C PMID of associated paper: 11306703 |
| Experimental Data: R296C PMID of associated paper: 11306703 |
| Experimental Data: C309A PMID of associated paper: 10455026 |
| Experimental Data: C309S PMID of associated paper: 11077047 |
| Experimental Data: E16Q PMID of associated paper: 8967987 |
| Experimental Data: S50A PMID of associated paper: 8967987 |
| Experimental Data: S93A PMID of associated paper: 8967987 |
| Experimental Data: R291 PMID of associated paper: 7657625 |
| Experimental Data: N184 PMID of associated paper: 7657625 |
| Experimental Data: E178 PMID of associated paper: 7657625 |
| Experimental Data: I292 PMID of associated paper: 7657625 |
| Experimental Data: M177 PMID of associated paper: 7657625 |
| Experimental Data: M180 PMID of associated paper: 7657625 |
| Experimental Data: F183 PMID of associated paper: 7657625 |
| Experimental Data: F259 PMID of associated paper: 7657625 |
| Experimental Data: Y179 PMID of associated paper: 7657625 |
| Experimental Data: Y182 PMID of associated paper: 7657625 |
| Experimental Data: V181 PMID of associated paper: 7657625 |
| Experimental Data: S50-S93 PMID of associated paper: 8967987 |
| Experimental Data: S93-S135 PMID of associated paper: 8967987 |
| Experimental Data: L65-M82 PMID of associated paper: 9920910 |
| Experimental Data: G14T PMID of associated paper: 9920910 |
| Experimental Data: E16A PMID of associated paper: 8967987 |
| Experimental Data: P25L PMID of associated paper: 9920910 |
| Experimental Data: C46A PMID of associated paper: 11077047 |
| Experimental Data: C46S PMID of associated paper: 11077047 |
| Experimental Data: D55A PMID of associated paper: 8967987 |
| Experimental Data: C85A PMID of associated paper: 11077047 |
| Experimental Data: C85S PMID of associated paper: 11077047 |
| Experimental Data: P86F PMID of associated paper: 9920910 |
| Experimental Data: V87A PMID of associated paper: 9920910 |
| Experimental Data: L88A PMID of associated paper: 9920910 |
| Experimental Data: T91A PMID of associated paper: 9920910 |
| Experimental Data: Q92A PMID of associated paper: 11891221 |
| Experimental Data: S94A PMID of associated paper: 8967987 |
| Experimental Data: S94T PMID of associated paper: 8967987 |
| Experimental Data: L96F PMID of associated paper: 9920910 |
| Experimental Data: C131A PMID of associated paper: 11077047 |
| Experimental Data: C131S PMID of associated paper: 11077047 |
| Experimental Data: H251L PMID of associated paper: 11891221 |
| Experimental Data: C255A PMID of associated paper: 11077047 |
| Experimental Data: C255S PMID of associated paper: 11077047 |
| Experimental Data: I268C PMID of associated paper: 11306703 |
| Experimental Data: L269C PMID of associated paper: 11306703 |
| Experimental Data: T270C PMID of associated paper: 11306703 |
| Experimental Data: Y271C PMID of associated paper: 11306703 |
| Experimental Data: I272C PMID of associated paper: 11306703 |
| Experimental Data: A273C PMID of associated paper: 11306703 |
| Experimental Data: I274C PMID of associated paper: 11306703 |
| Experimental Data: F275C PMID of associated paper: 11306703 |
| Experimental Data: L276C PMID of associated paper: 11306703 |
| Experimental Data: T277A PMID of associated paper: 10722120 |
| Experimental Data: T277C PMID of associated paper: 11306703 |
| Experimental Data: T277S PMID of associated paper: 8300561 |
| Experimental Data: H278C PMID of associated paper: 11306703 |
| Experimental Data: H278L PMID of associated paper: 11306703 |
| Experimental Data: G279C PMID of associated paper: 11306703 |
| Experimental Data: N280C PMID of associated paper: 11306703 |
| Experimental Data: S281C PMID of associated paper: 11306703 |
| Experimental Data: A282C PMID of associated paper: 11306703 |
| Experimental Data: M283C PMID of associated paper: 11306703 |
| Experimental Data: N284C PMID of associated paper: 11306703 |
| Experimental Data: P285C PMID of associated paper: 11306703 |
| Experimental Data: I286C PMID of associated paper: 11306703 |
| Experimental Data: V287C PMID of associated paper: 11306703 |
| Experimental Data: Y288C PMID of associated paper: 11306703 |
| Experimental Data: A289C PMID of associated paper: 11306703 |
| Experimental Data: F290C PMID of associated paper: 11306703 |
| Experimental Data: E16Q PMID of associated paper: 8967987 |
| Experimental Data: S50A PMID of associated paper: 8967987 |
| Experimental Data: S93A PMID of associated paper: 8967987 |
| Experimental Data: S135A PMID of associated paper: 8967987 |
| Experimental Data: T141A PMID of associated paper: 8967987 |
| Experimental Data: A237 PMID of associated paper: 7657625 |
| Experimental Data: A244 PMID of associated paper: 7657625 |
| Experimental Data: A273 PMID of associated paper: 7657625 |
| Experimental Data: A282 PMID of associated paper: 7657625 |
| Experimental Data: A289 PMID of associated paper: 7657625 |
| Experimental Data: N254 PMID of associated paper: 7657625 |
| Experimental Data: N280 PMID of associated paper: 7657625 |
| Experimental Data: N284 PMID of associated paper: 7657625 |
| Experimental Data: C255 PMID of associated paper: 7657625 |
| Experimental Data: G279 PMID of associated paper: 7657625 |
| Experimental Data: H251 PMID of associated paper: 7657625 |
| Experimental Data: H278 PMID of associated paper: 7657625 |
| Experimental Data: I199 PMID of associated paper: 7657625 |
| Experimental Data: I239 PMID of associated paper: 7657625 |
| Experimental Data: I252 PMID of associated paper: 7657625 |
| Experimental Data: I256 PMID of associated paper: 7657625 |
| Experimental Data: I268 PMID of associated paper: 7657625 |
| Experimental Data: I272 PMID of associated paper: 7657625 |
| Experimental Data: I274 PMID of associated paper: 7657625 |
| Experimental Data: I286 PMID of associated paper: 7657625 |
| Experimental Data: L190 PMID of associated paper: 7657625 |
| Experimental Data: L193 PMID of associated paper: 7657625 |
| Experimental Data: L194 PMID of associated paper: 7657625 |
| Experimental Data: L195 PMID of associated paper: 7657625 |
| Experimental Data: L198 PMID of associated paper: 7657625 |
| Experimental Data: L201 PMID of associated paper: 7657625 |
| Experimental Data: L236 PMID of associated paper: 7657625 |
| Experimental Data: L238 PMID of associated paper: 7657625 |
| Experimental Data: L240 PMID of associated paper: 7657625 |
| Experimental Data: L242 PMID of associated paper: 7657625 |
| Experimental Data: L245 PMID of associated paper: 7657625 |
| Experimental Data: L248 PMID of associated paper: 7657625 |
| Experimental Data: L250 PMID of associated paper: 7657625 |
| Experimental Data: L253 PMID of associated paper: 7657625 |
| Experimental Data: L258 PMID of associated paper: 7657625 |
| Experimental Data: L269 PMID of associated paper: 7657625 |
| Experimental Data: L276 PMID of associated paper: 7657625 |
| Experimental Data: M196 PMID of associated paper: 7657625 |
| Experimental Data: M283 PMID of associated paper: 7657625 |
| Experimental Data: F185 PMID of associated paper: 7657625 |
| Experimental Data: F186 PMID of associated paper: 7657625 |
| Experimental Data: F241 PMID of associated paper: 7657625 |
| Experimental Data: F243 PMID of associated paper: 7657625 |
| Experimental Data: F275 PMID of associated paper: 7657625 |
| Experimental Data: F290 PMID of associated paper: 7657625 |
| Experimental Data: P191 PMID of associated paper: 7657625 |
| Experimental Data: P192 PMID of associated paper: 7657625 |
| Experimental Data: P249 PMID of associated paper: 7657625 |
| Experimental Data: P285 PMID of associated paper: 7657625 |
| Experimental Data: S246 PMID of associated paper: 7657625 |
| Experimental Data: S281 PMID of associated paper: 7657625 |
| Experimental Data: T257 PMID of associated paper: 7657625 |
| Experimental Data: T270 PMID of associated paper: 7657625 |
| Experimental Data: T277 PMID of associated paper: 7657625 |
| Experimental Data: W188 PMID of associated paper: 7657625 |
| Experimental Data: W247 PMID of associated paper: 7657625 |
| Experimental Data: Y200 PMID of associated paper: 7657625 |
| Experimental Data: Y271 PMID of associated paper: 7657625 |
| Experimental Data: Y288 PMID of associated paper: 7657625 |
| Experimental Data: V187 PMID of associated paper: 7657625 |
| Experimental Data: V189 PMID of associated paper: 7657625 |
| Experimental Data: V197 PMID of associated paper: 7657625 |
| Experimental Data: V287 PMID of associated paper: 7657625 |
| Experimental Data: G14 PMID of associated paper: 9920910 |
| Experimental Data: P25 PMID of associated paper: 9920910 |
| Experimental Data: I31 PMID of associated paper: 9920910 |
| Experimental Data: L65 PMID of associated paper: 9920910 |
| Experimental Data: M82 PMID of associated paper: 9920910 |
| Experimental Data: A125 PMID of associated paper: 9920910 |
| Experimental Data: F144 PMID of associated paper: 9920910 |
| Experimental Data: P86 PMID of associated paper: 9920910 |
| Experimental Data: L96 PMID of associated paper: 9920910 |
| Experimental Data: MSA PMID of associated paper: 0 |
| GPCR Related Corss-reference Links: |
| GPCRDB GPCR-OKB UniProt_P30542 |