Experimental restraint
Download GPCR Model
Swiss ID: 5ht4r_human
Protein Name: 5-hydroxytryptamine 4 receptor (5-HT-4) (Serotonin
Organism: Homo sapiens (Human).
Seqeunce Length: 388
MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRD
AVECGGQWESQCHPPATSPLVAAQPSDT
Multiple Sequence Alignment
Experimental Restraints:
Contact Restraint: S197-F275  PMID of associated paper:  10821780
Contact Restraint: Y302-D66  PMID of associated paper:  10821780
Contact Restraint: D66-D100  PMID of associated paper:  10821780
MSA  PMID of associated paper:  0
Orientation Restraint: F276  PMID of associated paper:  10821780
Orientation Restraint: P149  PMID of associated paper:  10821780
Orientation Restraint: S197  PMID of associated paper:  10821780
Orientation Restraint: D66  PMID of associated paper:  10821780
Orientation Restraint: D100  PMID of associated paper:  10821780
Orientation Restraint: S153  PMID of associated paper:  10821780
Experimental Data:
Experimental Data: N279L  PMID of associated paper:  10821780
Experimental Data: F276V  PMID of associated paper:  10821780
Experimental Data: P149A  PMID of associated paper:  10821780
Experimental Data: S197A  PMID of associated paper:  10821780
Experimental Data: D66N  PMID of associated paper:  10821780
Experimental Data: D100N  PMID of associated paper:  10821780
Experimental Data: S153A  PMID of associated paper:  10821780
Experimental Data: S197-F275  PMID of associated paper:  10821780
Experimental Data: Y302-D66  PMID of associated paper:  10821780
Experimental Data: D66-D100  PMID of associated paper:  10821780
Experimental Data: F276V  PMID of associated paper:  10821780
Experimental Data: P149A  PMID of associated paper:  10821780
Experimental Data: S197A  PMID of associated paper:  10821780
Experimental Data: F275A  PMID of associated paper:  10821780
Experimental Data: Y302A  PMID of associated paper:  10821780
Experimental Data: D66N  PMID of associated paper:  10821780
Experimental Data: D100N  PMID of associated paper:  10821780
Experimental Data: T150V  PMID of associated paper:  10821780
Experimental Data: S153A  PMID of associated paper:  10821780
Experimental Data: C196A  PMID of associated paper:  10821780
Experimental Data: MSA  PMID of associated paper:  0
GPCR Related Corss-reference Links:
GPCRDB
GPCR-OKB
UniProt_Q13639