Detailed GPCR-I-TASSER Statistics for O00254

Submitted Sequence

>sp|O00254|PAR3_HUMAN
MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWT
GATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLF
FRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCS
ILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQP
DITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYV
KASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFL
MSKTRNHSTAYLTK

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |              
Sequence MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK
Prediction CCCHHHHHCCHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHSSSSCCCCCSSSSSSCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSCHHHHHHHHHHCC
Conf.Score 90048735120410543358888830103578999875667899987677997445676677777788898788886788986445664216885189999999999999999988986631677789999999999999999968999999847998988866799999999999999999999999984687640020244777402556779999999999989999722156068985799603897440179999999999999999999999999999999970577768738999999999999997899999999998741451479999999999999999988679674248418899997049

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |              
Sequence MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK
Prediction 32000100011000010003343454454344442314114344443234122432443434423373423434344242444134324440210000210120023033232100000001333210000000000021000000001000003443111020000000011121010000000000100010000002023223221000000001100110110100012034277432010002134743322010001121112012201200220000001102346542100000000001000001231010000200231052240020011001000020002000000000440141033027

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |              
Sec.Str
Seq		CCCHHHHHCCHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHSSSSCCCCCSSSSSSCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSCHHHHHHHHHHCC
MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK
15unfA 0.22 0.26 0.97 3.30Download LKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRH-GFDILVGQIDDAL----KLANEGKVKEAQAAAEQLKTTRNAHLDAIPILYYIIFVIGFLVNIVVVTLFCCQKGKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFPWQ-------ASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFP-PEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFR
25vblA 0.27 0.23 0.76 4.06Download ----------------------------------------------------------------------------------------DWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSRRRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASAFCLTGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTNKVQCYMDYSMVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAMKKEERRRLLSIIVVLVVTFALCKMPYHLVKTLYMLGSPCDFDLFLMNIFPYCTCISYVNSCLNPFLYAFFDPRFRQACTSMLL
35unfA 0.21 0.26 0.97 3.73Download LKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEG-----KVKEAQAAAEQLKTTRNAHLDAIPILYYIIFVIGFLVNIVVVTLFCCQKPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFP-------WQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPP-EKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFR
45nddA 0.36 0.31 0.79 3.85Download ---------------------------------------------------------------------------EFFSVDEFSASVLTGKLTTVFLPIVYTIVFVVALPSNGMALWVFLFRTKKAPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYANMYCSILFLTCLSVQRAWEIVNPMGHSR-KKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALQITTCHDVLP-EQLLVGDMFNYFLSLAIGVFLFPAFLTASAYVLMIRAL-NSEKKRKRAIKLAVTVAAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNAL-
55unfA 0.22 0.26 0.97 3.68Download LKVIEKADNAAQVKDALTKMRAAALDAQKATPPKL-----EDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAHLDAIPILYYIIFVIGFLVNIVVVTLFCCQKGKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFPW-------QASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPP-EKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSTRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFR
64djh 0.26 0.23 0.74 1.54Download -----------------------------------------------------------------------------------------SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRTKMKTATNIYIFNLALADALVTTTMPFQSTVYL-MNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDD-YSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSA------ALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCF
74rwaA 0.21 0.27 0.98 4.34Download NAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQTTRNAYIQKYLGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYKMKTATNIYIFNLALADALATSTLPFQSAKYLM-ETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRD--GAVVCMLQFPSP--SWYWDTVTKICVFLFAFVVPILIITVCYGLMLLGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLC-
84djh 0.27 0.23 0.74 1.18Download -----------------------------------------------------------------------------------------SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTMKTATNIYIFNLALADALVTTTMPFQSTVYLM-NSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDD-YSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSA------ALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCF
95unfA 0.21 0.26 0.98 4.38Download ADLEDNWETLNDNLKVIEKADNAAQRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAHLDAIPILYYIIFVIGFLVNIVVVTLFCCKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFPW-------QASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFP-PEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVIIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFR
104djh 0.27 0.23 0.73 1.72Download --------------------------------------------------------------------------------------------IPVIITAVYSVVFVVGLVGNSLVMFVIIRYKMKTATNIYIFNLALADALVTTTMPFQSTVYL-MNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDD-DYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSA------ALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFC-
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: Neff-PPAS   4: SPARKS-X   5: wdPPAS   6: HHSEARCH2   7: cdPPAS   8: HHSEARCH I   9: PROSPECT2   10: HHSEARCH   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=0.23 (Read more about C-score)
  • Estimated TM-score = 0.74±0.11
  • Estimated RMSD = 6.2±3.8Å

  • Download Model 2
  • C-score = -1.62

  • Download Model 3
  • C-score = -0.22

  • Download Model 4
  • C-score = -1.42

  • Download Model 5
  • C-score = -3.46


    • [Click on O00254_results.tar.bz2 to download the tarball file including all modeling results listed on this page]