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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SC46275
Molecular formula	C25H36O5
IUPAC name	methyl (Z)-7-[(1R,2R,3R)-2-[(1E,4R,5E)-6-(cyclopenten-1-yl)-4-hydroxy-4-methylhexa-1,5-dienyl]-3-hydroxy-5-oxocyclopentyl]hept-4-enoate
Molecular weight	416.558
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.8
Synonyms	Remiprostol, (1S,2S,3S,4'S)-(+/-)- AC1NSKM3 FZ6T2MQR9R UNII-FZ6T2MQR9R 110902-56-2 methyl (Z)-7-[(1R,2R,3R)-2-[(1E,4R,5E)-6-(cyclopenten-1-yl)-4-hydroxy-4-methylhexa-1,5-dienyl]-3-hydroxy-5-oxocyclopentyl]hept-4-enoate 4-Heptenoic acid, 7-((1R,2R,3R)-2-((1E,4R,5E)-6-(1-cyclopenten-1-yl)-4-hydroxy-4-methyl-1,5-hexadien-1-yl)-3-hydroxy-5-oxocyclopentyl)-, methyl ester, (4Z)-rel- CHEMBL49922 SC-46275 GTPL3331 UNII-NYG10Z50BH component ZZVPHCPLTZTOBC-ZNJGPPGCSA-N 137255-19-7 Remiprostol, (1R,2R,3R,4'R)-(+/-)- 4-Heptenoic acid, 7-(2-(6-(1-cyclopenten-1-yl)-4-hydroxy-4-methyl-1,5-hexadienyl)-3-hydroxy-5-oxocyclopentyl)-, methyl ester, (1alpha(Z),2beta(1E,4R*,5E),3alpha)-(+/-)- D0L8DV methyl (4Z)-7-[(1R,2R,3R)-2-[(1E,4R,5E)-6-(cyclopent-1-en-1-yl)-4-hydroxy-4-methylhexa-1,5-dien-1-yl]-3-hydroxy-5-oxocyclopentyl]hept-4-enoate UNII-YCT6Z40PQR component ZZVPHCPLTZTOBC-ZNJGPPGCSA-N [ Show all ]
Inchi Key	ZZVPHCPLTZTOBC-ZNJGPPGCSA-N
Inchi ID	InChI=1S/C25H36O5/c1-25(29,17-15-19-10-7-8-11-19)16-9-13-21-20(22(26)18-23(21)27)12-5-3-4-6-14-24(28)30-2/h3-4,9-10,13,15,17,20-21,23,27,29H,5-8,11-12,14,16,18H2,1-2H3/b4-3-,13-9+,17-15+/t20-,21-,23-,25-/m1/s1
PubChem CID	5311427
ChEMBL	N/A
IUPHAR	3331
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
555475	Prostaglandin E2 receptor EP3 subtype	P34980	Ptger3	Rattus norvegicus (Rat)	365

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