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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL472288
Molecular formula	C26H35Cl2N5O
IUPAC name	5-chloro-6-[(3S)-4-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-3-ethylpiperazin-1-yl]-N-ethylpyridine-3-carboxamide
Molecular weight	504.5
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.1
Synonyms	N-Ethyl-2-[3alpha-ethyl-4-[1-(4-chlorobenzyl)piperidine-4-yl]piperazine-1-yl]-3-chloropyridine-5-carboxamide (S)-5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)-3-ethylpiperazin-1-yl)-N-ethylnicotinamide SCHEMBL13205647 BDBM50337250
Inchi Key	XQWKNLJIWOTOKT-QFIPXVFZSA-N
Inchi ID	InChI=1S/C26H35Cl2N5O/c1-3-22-18-32(25-24(28)15-20(16-30-25)26(34)29-4-2)13-14-33(22)23-9-11-31(12-10-23)17-19-5-7-21(27)8-6-19/h5-8,15-16,22-23H,3-4,9-14,17-18H2,1-2H3,(H,29,34)/t22-/m0/s1
PubChem CID	44592137
ChEMBL	CHEMBL472288
IUPHAR	N/A
BindingDB	50337250
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
398693	C-X-C chemokine receptor type 3	Q9JII9	Cxcr3	Rattus norvegicus (Rat)	367
398694	C-X-C chemokine receptor type 3	P49682	CXCR3	Homo sapiens (Human)	368
398695	C-X-C chemokine receptor type 3	O88410	Cxcr3	Mus musculus (Mouse)	367

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