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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3290093
Molecular formula	C27H23ClF2N4O3
IUPAC name	(2S)-2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-difluorophenyl)pyrazole-3-carbonyl]amino]-2-cyclohexylacetic acid
Molecular weight	524.953
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	6.3
Synonyms	BDBM50019409 SCHEMBL17114547
Inchi Key	XJSGFYNGKBZELF-VWLOTQADSA-N
Inchi ID	InChI=1S/C27H23ClF2N4O3/c28-16-9-10-17-20(13-16)31-12-11-22(17)34-23(24-18(29)7-4-8-19(24)30)14-21(33-34)26(35)32-25(27(36)37)15-5-2-1-3-6-15/h4,7-15,25H,1-3,5-6H2,(H,32,35)(H,36,37)/t25-/m0/s1
PubChem CID	90644386
ChEMBL	CHEMBL3290093
IUPHAR	N/A
BindingDB	50019409
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
393642	Neurotensin receptor type 1	P20789	Ntsr1	Rattus norvegicus (Rat)	424
393641	Neurotensin receptor type 2	Q63384	Ntsr2	Rattus norvegicus (Rat)	416

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