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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL145103
Molecular formula	C28H28N2O
IUPAC name	4-[(2-benzhydryl-1-azabicyclo[2.2.2]octan-3-yl)oxymethyl]benzonitrile
Molecular weight	408.545
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.4
Synonyms	4-(2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yloxymethyl)-benzonitrile SCHEMBL8799805 BDBM50029849 L007238
Inchi Key	VXGPTRVARWWDQI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H28N2O/c29-19-21-11-13-22(14-12-21)20-31-28-25-15-17-30(18-16-25)27(28)26(23-7-3-1-4-8-23)24-9-5-2-6-10-24/h1-14,25-28H,15-18,20H2
PubChem CID	11661466
ChEMBL	CHEMBL145103
IUPHAR	N/A
BindingDB	50029849
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
531821	Mas-related G-protein coupled receptor member X1	Q8R4G1	Mrgprx1	Rattus norvegicus (Rat)	323
531822	Mas-related G-protein coupled receptor member X1	Q96LB2	MRGPRX1	Homo sapiens (Human)	322
366511	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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