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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL107238
Molecular formula	C22H30N4O4
IUPAC name	(3S,8aS)-7-cyclohexyl-6-[(5R)-2,6-dioxo-1,7-diazaspiro[4.4]nonan-7-yl]-5-oxo-2,3,8,8a-tetrahydro-1H-indolizine-3-carboxamide
Molecular weight	414.506
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	0.9
Synonyms	7-cyclohexyl-6-(2,6-dioxo-1,7-diazaspiro[4.4]non-7-yl)-5-oxo-(8aR)-1,2,3,5,8,8a-hexahydro-3-indolizinecarboxamide BDBM50072396
Inchi Key	UHPPHOTXFKINLG-KHJUTWJGSA-N
Inchi ID	InChI=1S/C22H30N4O4/c23-19(28)16-7-6-14-12-15(13-4-2-1-3-5-13)18(20(29)26(14)16)25-11-10-22(21(25)30)9-8-17(27)24-22/h13-14,16H,1-12H2,(H2,23,28)(H,24,27)/t14-,16-,22+/m0/s1
PubChem CID	9979181
ChEMBL	CHEMBL107238
IUPHAR	N/A
BindingDB	50072396
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
336991	Thyrotropin-releasing hormone receptor	P21761	Trhr	Mus musculus (Mouse)	393

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